CAJ | 학술논문

酒渣鼻是面部常见的皮肤病,影响患者的身心健康,其发病机制尚未完全阐明,可能的诱因较多.蠕形螨感染是诱发酒渣鼻的重要因素,其引起皮肤损害的可能机制包括:机械地阻塞毛囊,导致毛囊扩展,引起过度角化;螨的几丁质外骨骼有助于肉芽肿的形成;蠕形螨的排泄物可能会激活免疫系统出现迟发型超敏反应等.该文就蠕形螨诱导并维持酒渣鼻的机制进行综述,旨在探究更合适的治疗方法.
주사비시면부상견적피부병,영향환자적신심건강,기발병궤제상미완전천명,가능적유인교다.연형만감염시유발주사비적중요인소,기인기피부손해적가능궤제포괄:궤계지조새모낭,도치모낭확전,인기과도각화;만적궤정질외골격유조우육아종적형성;연형만적배설물가능회격활면역계통출현지발형초민반응등.해문취연형만유도병유지주사비적궤제진행종술,지재탐구경합괄적치료방법.
Rosacea is a common chronic inflammatory dermatosis of the face,influencing the physical and mental health of the pateints.The etiopathogenesis of rosacea remains unexplained,there are many factors predisposing it.The causal relationship of Demodex mites in skin lesions has been suspected to occur through several mechanisms.They may mechanically block the follicles,leading to distension and causing intrafollicular hyperkeratosis.The presence of mite's chitinous external skeleton may act as a foreign body and contribute to the formation of granulomas.The waste products of Demodex mites may stimulate the immune system through the mechanism of delayed hypersensitivity reaction.This review summarised the literature relating to the role of Demodex mites in the induction and persistence of rosacea and highlighted the possible therapeutic options.