CAJ | 학술논문

旋毛虫病是一种常见的人兽共患寄生虫病,也是一种重要的食源性寄生虫病,严重危害着人体的健康.树突状细胞是固有性免疫细胞的一种,也是宿主肠道黏膜免疫系统最重要的一种抗原呈递细胞,与宿主肠道免疫系统关系密切.近年来有关树突状细胞在寄生虫感染与宿主免疫应答中的作用,尤其在旋毛虫感染与免疫的作用,备受人们的关注.该文就目前国内有关旋毛虫感染后,宿主树突状细胞参与肠黏膜的一系列免疫应答反应和发挥作用的研究进展做一综述.
선모충병시일충상견적인수공환기생충병,야시일충중요적식원성기생충병,엄중위해착인체적건강.수돌상세포시고유성면역세포적일충,야시숙주장도점막면역계통최중요적일충항원정체세포,여숙주장도면역계통관계밀절.근년래유관수돌상세포재기생충감염여숙주면역응답중적작용,우기재선모충감염여면역적작용,비수인문적관주.해문취목전국내유관선모충감염후,숙주수돌상세포삼여장점막적일계렬면역응답반응화발휘작용적연구진전주일종술.
Trichinosis is one of the most common zoonotic parasitic diseases,a kind of important foodborne parasitic disease with serious harm to human health.Dendritic cells are a kind of innate immune cells.As one of the most important antigen-presenting cells in the intestinal mucosal immune system of the host,it is closely related to the intestinal immune system.In recent years,its effect on parasite infection and host immune responses,especially in the Trichinella spiralis infection and immunity has attracted people's attention.In this review,the research progress at home and abroad on the host intestinal mucosal dendritic cells involved in a series of immunological reactions and roles in Trichinella infection was reviewed.