国际医学寄生虫病杂志
國際醫學寄生蟲病雜誌
국제의학기생충병잡지
INTERNATIONAL JOURNAL OF MEDICAL PARASITIC DISEASES
2014年
2期
61-65
,共5页
许毅从%段琼红%邹先胜%蔡栋%朱晓华
許毅從%段瓊紅%鄒先勝%蔡棟%硃曉華
허의종%단경홍%추선성%채동%주효화
晚期血吸虫病%伤残权重%疾病负担%通径分析
晚期血吸蟲病%傷殘權重%疾病負擔%通徑分析
만기혈흡충병%상잔권중%질병부담%통경분석
Advanced schistosomiasis%Disability weight%Burden of disease%Path analysis
目的 发展适合我国晚期血吸虫病疾病负担评价的伤残权重,并分析伤残权重的影响因素,为评估其疾病负担提供参考依据. 方法 以全球疾病负担研究中疾病的六级失能等级标准为依据,评定我国晚期血吸虫病的年龄别和性别平均伤残权重.通过问卷调查的方式对湖北省阳新县125例晚期血吸虫病患者进行调查,全部数据采用EpiData3.1软件建库,应用SAS8.1软件进行分析.分别采用Wilcoxon秩和检验、Kruskal-Wallis秩和检验比较性别和年龄别伤残权重,用Nemenyi法对年龄别伤残权重进行两两比较,并通过通径分析模型分析伤残权重的影响因素. 结果 我国湖区晚期血吸虫病患者伤残权重均值为0.307.年龄别伤残权重为0.096～0.377,高于全球疾病负担研究中确定的0.005～0.006.伤残权重值随着年龄增长呈上升趋势,年龄组差异有统计学意义(x2=34.559,P＜ 0.01).男、女性伤残权重分别为0.265和0.357,女性明显高于男性,差异具有统计学意义(Z=2.503,P＜ 0.05).通径分析显示:对伤残权重有直接作用的变量按作用大小依次为年龄,患病年数,收入水平,性别、营养不良、消瘦,文化程度,贫血和记忆力下降;有间接作用的变量按作用大小依次为年龄、收入水平、患病年数和性别;总体影响前3位的分别为年龄、患病年数、收入水平. 结论 晚期血吸虫病患者每存活1年平均损失近3/10个健康寿命年.该评定结果高于全球疾病负担研究的确定值,初步反映了我国晚期血吸虫病患者的失能情况.
目的 髮展適閤我國晚期血吸蟲病疾病負擔評價的傷殘權重,併分析傷殘權重的影響因素,為評估其疾病負擔提供參攷依據. 方法 以全毬疾病負擔研究中疾病的六級失能等級標準為依據,評定我國晚期血吸蟲病的年齡彆和性彆平均傷殘權重.通過問捲調查的方式對湖北省暘新縣125例晚期血吸蟲病患者進行調查,全部數據採用EpiData3.1軟件建庫,應用SAS8.1軟件進行分析.分彆採用Wilcoxon秩和檢驗、Kruskal-Wallis秩和檢驗比較性彆和年齡彆傷殘權重,用Nemenyi法對年齡彆傷殘權重進行兩兩比較,併通過通徑分析模型分析傷殘權重的影響因素. 結果 我國湖區晚期血吸蟲病患者傷殘權重均值為0.307.年齡彆傷殘權重為0.096～0.377,高于全毬疾病負擔研究中確定的0.005～0.006.傷殘權重值隨著年齡增長呈上升趨勢,年齡組差異有統計學意義(x2=34.559,P＜ 0.01).男、女性傷殘權重分彆為0.265和0.357,女性明顯高于男性,差異具有統計學意義(Z=2.503,P＜ 0.05).通徑分析顯示:對傷殘權重有直接作用的變量按作用大小依次為年齡,患病年數,收入水平,性彆、營養不良、消瘦,文化程度,貧血和記憶力下降;有間接作用的變量按作用大小依次為年齡、收入水平、患病年數和性彆;總體影響前3位的分彆為年齡、患病年數、收入水平. 結論 晚期血吸蟲病患者每存活1年平均損失近3/10箇健康壽命年.該評定結果高于全毬疾病負擔研究的確定值,初步反映瞭我國晚期血吸蟲病患者的失能情況.
목적 발전괄합아국만기혈흡충병질병부담평개적상잔권중,병분석상잔권중적영향인소,위평고기질병부담제공삼고의거. 방법 이전구질병부담연구중질병적륙급실능등급표준위의거,평정아국만기혈흡충병적년령별화성별평균상잔권중.통과문권조사적방식대호북성양신현125례만기혈흡충병환자진행조사,전부수거채용EpiData3.1연건건고,응용SAS8.1연건진행분석.분별채용Wilcoxon질화검험、Kruskal-Wallis질화검험비교성별화년령별상잔권중,용Nemenyi법대년령별상잔권중진행량량비교,병통과통경분석모형분석상잔권중적영향인소. 결과 아국호구만기혈흡충병환자상잔권중균치위0.307.년령별상잔권중위0.096～0.377,고우전구질병부담연구중학정적0.005～0.006.상잔권중치수착년령증장정상승추세,년령조차이유통계학의의(x2=34.559,P＜ 0.01).남、녀성상잔권중분별위0.265화0.357,녀성명현고우남성,차이구유통계학의의(Z=2.503,P＜ 0.05).통경분석현시:대상잔권중유직접작용적변량안작용대소의차위년령,환병년수,수입수평,성별、영양불량、소수,문화정도,빈혈화기억력하강;유간접작용적변량안작용대소의차위년령、수입수평、환병년수화성별;총체영향전3위적분별위년령、환병년수、수입수평. 결론 만기혈흡충병환자매존활1년평균손실근3/10개건강수명년.해평정결과고우전구질병부담연구적학정치,초보반영료아국만기혈흡충병환자적실능정황.
Objective To establish suitable disability weights for advanced schistosomiasis japonica in China and analyze its influential factors,so as to offer the reference for quantifying the burden of the disease of schistosomiasis.Methods Based on the criteria of a six classes of disability in global burden of disease (GBD),average disability weights for advanced schistosomiasis japonica were obtained by age and gender.One hundred and twenty-five advanced schistosomiasis patients from Yangxin County were investigated by questionnaire.The whole data was managed by Epidata 3.1 and analyzed by SAS8.1.The gender-specific and age-specific weight were compared using Wilcoxon test and Kruskal-Wallis test,respectively.Pairwise comparisons of age-specific weight were analyzed by Nemenyi method.The path analysis was used to analyze the influential factors of disability weight.Results The average disability weight of advanced schistosomiasis japonica in lake regions was 0.307.The age-specific disability weight ranged from 0.096 to 0.377,which was higher than the level of 0.005 ～ 0.006 identified by GBD,and the disability weights increased with age.The difference between age groups was significant (x2 =34.559,P＜ 0.01).It was assigned that a disability weight of 0.265 in male and 0.357 in female,and the difference between two genders was significant (Z=2.503,P＜ 0.05).Path analysis showed that direct influential factors were age,illness years,income levels,gender,weight loss,education,anemia and memory decline by the order,and the indirect influential factors were age,income levels,illness years and gender.The top three influential factors were age,illness years and income levels.Conclusion The average disability weight of 0.307 for advanced schistosomiasis japonica indicated that 3/10 healthy year lost for each survived life year of the patients.The disability weight resulted from this study was higher than that in the data of GBD.This disability weight was suitable for the advanced schistosomiasis patients in lake regions of China.
