CAJ | 학술논문

目的探讨一起肾综合征出血热(HFRS)疫情的流行因素,为HFRS的预防控制提供科学依据.方法收集相关流行病学资料,采用夹夜法观察营区周围鼠密度,收集可能暴露和接触人群血清样本.用间接免疫荧光试验检测汉坦病毒抗体或抗原,用RT-PCR法进行核酸检测.结果 2例患者分别于入营后12 d和17 d发病,确诊为HFRS.营区外鼠密度为1.00％.共捕获褐家鼠2只,鼠血清抗体阳性率和病毒携带率为0.可能暴露及密切接触人群血清抗体阳性率为2.04％,病毒核酸检测阴性.结论该疫情为一起输入性HFRS疫情,提示应加强疫情监测和检疫,防止疫情蔓延.
목적 탐토일기신종합정출혈열(HFRS)역정적류행인소,위HFRS적예방공제제공과학의거.방법 수집상관류행병학자료,채용협야법관찰영구주위서밀도,수집가능폭로화접촉인군혈청양본.용간접면역형광시험검측한탄병독항체혹항원,용RT-PCR법진행핵산검측.결과 2례환자분별우입영후12 d화17 d발병,학진위HFRS.영구외서밀도위1.00％.공포획갈가서2지,서혈청항체양성솔화병독휴대솔위0.가능폭로급밀절접촉인군혈청항체양성솔위2.04％,병독핵산검측음성.결론 해역정위일기수입성HFRS역정,제시응가강역정감측화검역,방지역정만연.
Objective To determine the risk factors of a hemorrhagic fever with renal syndrome (HFRS) outbreak,in order to provide scientific basis for HFRS prevention and control.Methods Epidemiological data were collected.The mouse density was monitored trap-at-night method.The serum samples of the people who contacted with the patients were acquired.The HFRS antibody was detected by indirect immunofluorescence assay and the virus nucleic acid was tested by RT-PCR.Results The onset time of 2 cases were 12 and 17 days after enlistment,and they were diagnosed as HFRS respectively.The mouse density was 1.00％ around the military camp,and 2 Norway rats were captured.The hantavirus antibody positive rate and virus carried rate of the rats were 0.The serum antibody positive rate of the people who contacted with the patients was 2.04％,and the virus nucleic acid were negative.Conclusions The epidemic is proved to be imported by HFRS cases.It is necessary to reinforce epidemic surveillance to prevent HFRS epidemic.