CAJ | 학술논문

Epstein-Barr病毒(EB病毒)与传染性单核细胞增多症、继发性噬血细胞性淋巴组织细胞增生症和鼻咽癌等相关,是重要的肿瘤相关病毒.EBERs是EB病毒潜伏感染的细胞内数量最多的病毒转录产物,可能在潜伏感染及细胞转化中发挥重要的作用.此文综述了EBER基因变异及EBERs的生物学特性.
Epstein-Barr병독(EB병독)여전염성단핵세포증다증、계발성서혈세포성림파조직세포증생증화비인암등상관,시중요적종류상관병독.EBERs시EB병독잠복감염적세포내수량최다적병독전록산물,가능재잠복감염급세포전화중발휘중요적작용.차문종술료EBER기인변이급EBERs적생물학특성.
Epstein-Barr virus(EBV) is associated with infectious mononucleosis,secondary hemophagocytic lymphohistiocytosis and nasopharyngeal carcinoma.It is one of human tumor-associated virus.EBERs are the most abundant viral transcripts in EBV latent infection cells,and may play an important role in latent infection and cell transformation.The variation of EBERs and the advances on biological function of EBERs are reviewed briefly in this article.