国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
2期
186-188
,共3页
余明杰%许瑞香%余洽超%杨丽虹
餘明傑%許瑞香%餘洽超%楊麗虹
여명걸%허서향%여흡초%양려홍
咪达唑仑%新生儿%机械通气%镇静
咪達唑崙%新生兒%機械通氣%鎮靜
미체서륜%신생인%궤계통기%진정
Midazolam%Newborn%Mechanical ventilation%Sedation
目的 探讨咪达唑仑对在机械通气中的新生儿镇静临床价值.方法 回顾性总结本科2006年7月至2011年6月在我院新生儿科收住的需要机械通气的新生儿病例,并依据是否使用咪达唑仑镇静随机将患儿分为两组:对照组32例给予常规安定、苯巴比妥类和水合氯醛等镇静处理;观察组30例使用咪达唑仑镇静.总结对比两组患儿的镇静效果;呼吸机参数;脱管率;应用机械通气时间,并进行分析.结果 观察组应用咪达唑仑后0.5、2、24、48 h无操作时与对照组的评分差异均有显著性(P＜0.05).观察组用咪达唑仑后吸气峰压、氧浓度及呼吸频率下调明显,与对照组的差异均有显著性(P＜0.05).因烦躁不安脱管观察组无一例,对照组有12例,差异均有显著性(P＜0.05).应用机械通气时间观察组(81.3±17.7)h明显少于对照组(102.4±19.3)h,差异均有极显著性(t=2.8,P＜0.01).结论 在新生儿机械通气治疗中咪达唑仑能恰当有效的镇静,减少由于气管插管和吸痰等侵人性操作引起烦躁不安导致的人机对抗.
目的 探討咪達唑崙對在機械通氣中的新生兒鎮靜臨床價值.方法 迴顧性總結本科2006年7月至2011年6月在我院新生兒科收住的需要機械通氣的新生兒病例,併依據是否使用咪達唑崙鎮靜隨機將患兒分為兩組:對照組32例給予常規安定、苯巴比妥類和水閤氯醛等鎮靜處理;觀察組30例使用咪達唑崙鎮靜.總結對比兩組患兒的鎮靜效果;呼吸機參數;脫管率;應用機械通氣時間,併進行分析.結果 觀察組應用咪達唑崙後0.5、2、24、48 h無操作時與對照組的評分差異均有顯著性(P＜0.05).觀察組用咪達唑崙後吸氣峰壓、氧濃度及呼吸頻率下調明顯,與對照組的差異均有顯著性(P＜0.05).因煩躁不安脫管觀察組無一例,對照組有12例,差異均有顯著性(P＜0.05).應用機械通氣時間觀察組(81.3±17.7)h明顯少于對照組(102.4±19.3)h,差異均有極顯著性(t=2.8,P＜0.01).結論 在新生兒機械通氣治療中咪達唑崙能恰噹有效的鎮靜,減少由于氣管插管和吸痰等侵人性操作引起煩躁不安導緻的人機對抗.
목적 탐토미체서륜대재궤계통기중적신생인진정림상개치.방법 회고성총결본과2006년7월지2011년6월재아원신생인과수주적수요궤계통기적신생인병례,병의거시부사용미체서륜진정수궤장환인분위량조:대조조32례급여상규안정、분파비타류화수합록철등진정처리;관찰조30례사용미체서륜진정.총결대비량조환인적진정효과;호흡궤삼수;탈관솔;응용궤계통기시간,병진행분석.결과 관찰조응용미체서륜후0.5、2、24、48 h무조작시여대조조적평분차이균유현저성(P＜0.05).관찰조용미체서륜후흡기봉압、양농도급호흡빈솔하조명현,여대조조적차이균유현저성(P＜0.05).인번조불안탈관관찰조무일례,대조조유12례,차이균유현저성(P＜0.05).응용궤계통기시간관찰조(81.3±17.7)h명현소우대조조(102.4±19.3)h,차이균유겁현저성(t=2.8,P＜0.01).결론 재신생인궤계통기치료중미체서륜능흡당유효적진정,감소유우기관삽관화흡담등침인성조작인기번조불안도치적인궤대항.
Objective To explore midazolam on mechanical ventilation in the neonatal calm clinical value.Methods Retrospective summary undergraduate course in July 2006 to June 2011 freshmen in our hospital pediatric our need to mechanical ventilation of neonatal cases,On the basis of whether using midazolam calm random children will be divided into two groups:The control group 32 examples given conventional stability,benzene barbitone class and chloral hydrate etc calm processing;The observation group 30 cases using midazolam calm.Summary compared to two groups of children calm effect; Breathing machine parameter; To take off the tube rate;Application of mechanical ventilation time and to carry on the analysis.Results The observation group application midazolam after 0.5,2,24,48 h with no operation control score differences were statistically significant (P ＜0.05).The observation group with midazolam after inspiratory peak pressure,oxygen concentration and respiratory frequency down significantly,compare dwith the differences were statistically significant (P ＜ 0.05).Because of the dysphoria to take off the tube observation group no case and control group in 12 cases,the differences were statistically significant (P ＜ 0.05).Application of mechanical ventilation time observation group (81.3 + 17.7)H is less than that of control group (102.4 + 19.3 )H,the differences were statistically significant (P ＜ 0.01).ConclUsions In neonatal mechanical ventilation treatment midazolam can appropriate effective calm,Reduce the endotracheal intubation and sputum aspiration and invasive operation cause dysphoria in man-machine confrontation.
