国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2014年
4期
261-263
,共3页
潘庆登%陈志强%黄永康%陆智东%何岳%钟丽娟%何传雄
潘慶登%陳誌彊%黃永康%陸智東%何嶽%鐘麗娟%何傳雄
반경등%진지강%황영강%륙지동%하악%종려연%하전웅
颈动脉狭窄%危险因素%Logistic回归分析
頸動脈狹窄%危險因素%Logistic迴歸分析
경동맥협착%위험인소%Logistic회귀분석
Carotid stenosis%Risk factor%Logistic regression analysis
目的 了解颈动脉斑块形成的危险因素,为更好地防治颈动脉斑块形成提供依据.方法 收集2008年7月至2014年2月在北海市第二人民医院住院治疗的723例患者,其中492例伴有颈动脉斑块(斑块组),231例无颈动脉斑块(无斑块组).所有病例均常规检测总胆固醇(TC)、低密度胆固醇(LDL)、甘油三酯(TG)和高密度胆固醇(HDL),并用彩超检查颈动脉斑块,将性别、年龄、高血压、糖尿病、TC、LDL、TG和HDL多个颈动脉斑块形成的危险因素进行Logistic回归分析.结果 斑块组平均年龄(72.20±11.12)岁,高于无斑块组,差异有统计学意义(t=9.909,P＜0.01);且血清TC、TG和LDL分别为(5.38±1.41)、(1.63±0.91)和(3.56±1.18) mmol/L,也均高于无斑块组,差异均有统计学意义(t=5.255、2.785、5.261,P均＜0.01),而两组HDL比较,差异无统计学意义(t=-1.096,P＞0.05).Logistic回归分析显示,男性(OR=1.571,95％CI:1.116～2.212)、年龄≥65岁(OR=3.116,95％CI:2.201～4.410)、高血压(OR=1.699,95％ CI:1.184～2.438)、LDL≥3.3 mmol/L(OR=1.779,95％CI:1.161～2.726)和TG≥1.8 mmol/L(OR=1.575,95％CI:1.064～2.333)5种因素可能与颈动脉斑块的形成相关.结论 男性、年龄≥65岁、高血压、LDL≥3.3 mmol/L和TG≥1.8 mmol/L为颈动脉斑块形成的危险因素.
目的 瞭解頸動脈斑塊形成的危險因素,為更好地防治頸動脈斑塊形成提供依據.方法 收集2008年7月至2014年2月在北海市第二人民醫院住院治療的723例患者,其中492例伴有頸動脈斑塊(斑塊組),231例無頸動脈斑塊(無斑塊組).所有病例均常規檢測總膽固醇(TC)、低密度膽固醇(LDL)、甘油三酯(TG)和高密度膽固醇(HDL),併用綵超檢查頸動脈斑塊,將性彆、年齡、高血壓、糖尿病、TC、LDL、TG和HDL多箇頸動脈斑塊形成的危險因素進行Logistic迴歸分析.結果 斑塊組平均年齡(72.20±11.12)歲,高于無斑塊組,差異有統計學意義(t=9.909,P＜0.01);且血清TC、TG和LDL分彆為(5.38±1.41)、(1.63±0.91)和(3.56±1.18) mmol/L,也均高于無斑塊組,差異均有統計學意義(t=5.255、2.785、5.261,P均＜0.01),而兩組HDL比較,差異無統計學意義(t=-1.096,P＞0.05).Logistic迴歸分析顯示,男性(OR=1.571,95％CI:1.116～2.212)、年齡≥65歲(OR=3.116,95％CI:2.201～4.410)、高血壓(OR=1.699,95％ CI:1.184～2.438)、LDL≥3.3 mmol/L(OR=1.779,95％CI:1.161～2.726)和TG≥1.8 mmol/L(OR=1.575,95％CI:1.064～2.333)5種因素可能與頸動脈斑塊的形成相關.結論 男性、年齡≥65歲、高血壓、LDL≥3.3 mmol/L和TG≥1.8 mmol/L為頸動脈斑塊形成的危險因素.
목적 료해경동맥반괴형성적위험인소,위경호지방치경동맥반괴형성제공의거.방법 수집2008년7월지2014년2월재북해시제이인민의원주원치료적723례환자,기중492례반유경동맥반괴(반괴조),231례무경동맥반괴(무반괴조).소유병례균상규검측총담고순(TC)、저밀도담고순(LDL)、감유삼지(TG)화고밀도담고순(HDL),병용채초검사경동맥반괴,장성별、년령、고혈압、당뇨병、TC、LDL、TG화HDL다개경동맥반괴형성적위험인소진행Logistic회귀분석.결과 반괴조평균년령(72.20±11.12)세,고우무반괴조,차이유통계학의의(t=9.909,P＜0.01);차혈청TC、TG화LDL분별위(5.38±1.41)、(1.63±0.91)화(3.56±1.18) mmol/L,야균고우무반괴조,차이균유통계학의의(t=5.255、2.785、5.261,P균＜0.01),이량조HDL비교,차이무통계학의의(t=-1.096,P＞0.05).Logistic회귀분석현시,남성(OR=1.571,95％CI:1.116～2.212)、년령≥65세(OR=3.116,95％CI:2.201～4.410)、고혈압(OR=1.699,95％ CI:1.184～2.438)、LDL≥3.3 mmol/L(OR=1.779,95％CI:1.161～2.726)화TG≥1.8 mmol/L(OR=1.575,95％CI:1.064～2.333)5충인소가능여경동맥반괴적형성상관.결론 남성、년령≥65세、고혈압、LDL≥3.3 mmol/L화TG≥1.8 mmol/L위경동맥반괴형성적위험인소.
Objective To investigate the risk factors of atherosclerotic plaque in the carotid,in an attempt to find better measures for prevention and treatment of the disease.Methods A total of 723 patients admitted in the Second People's Hospital of Beihai from July 2008 to February 2014 were enrolled and were divided into carotid plaque group(n=492) and non-carotid-plaque group (n=231).The contents of otal cholesterol (TC),low density lipoprotein cholesterol (LDL),triglyceride (TG) and high density lipoprote cholesterolin (HDL) in all patients were detected,and color doppler ultrasound was used to detect carotid plaque.Risk factors were analyzed by logistic regression.Results The mean age was(72.20±1 1.12) years in carotid plaque group,older than that in non-carotid-plaque group with a significant difference (t=9.909,P＜0.01).Compared with non-carotid-plaque group,the levels of TC (5.38±1.41 mmol/L),TG (1.63±0.91 mmol/L)and LDL-C (3.56±1.18 mmol/L) were significantly higher in carotid plaque group (t=5.255,2.785,5.261,all P＜0.01); the level of HDL did not differ between two groups (t=-1.096,P＞0.05).Logistic regression analysis showed that male (OR=1.571,95％CI:1.116-2.212),older than 65 years (OR=3.116,95％CI:2.201-4.410),hypertension (OR=1.699,95％CI:1.184-2.438),LDL≥3.3 mmol/L (OR=1.779,95％CI:1.1611-2.726),and TG≥ 1.8 mmol/L (OR=1.575,95％CI:1.064-2.333) were risk factors associated with the prevalence of atherosclerotic plaque in the carotid.Conclusions Male,older than 65 years,hypertension,LDL ≥3.3 mmol/L,and TG ≥ 1.8 mmol/L are risk factors of carotid atherosclerotic plaque.
