CAJ | 학술논문

布鲁杆菌病是一种人畜共患性传染病,人感染布鲁杆菌由于缺乏特异性的临床症状和体征,极易被误诊为其他疾病.布鲁杆菌感染是目前的研究热点,研究者试图从分子水平阐述其致病机制.另外,布鲁杆菌病临床表现发生一些新变化,呈单一或多个器官或系统受累,临床诊断治疗和预防也有新进展.基于此,文章将对布鲁杆菌致病机制以及布鲁杆菌病的临床变化新特点和诊治等方面作一综述.
포로간균병시일충인축공환성전염병,인감염포로간균유우결핍특이성적림상증상화체정,겁역피오진위기타질병.포로간균감염시목전적연구열점,연구자시도종분자수평천술기치병궤제.령외,포로간균병림상표현발생일사신변화,정단일혹다개기관혹계통수루,림상진단치료화예방야유신진전.기우차,문장장대포로간균치병궤제이급포로간균병적림상변화신특점화진치등방면작일종술.
Brucellosis is a zoonotic infectious disease,and human infected can easily be misdiagnosed as having other diseases because its specific clinical manifestations have not been identified.The mechanism of Brucella infection is a current hotspot.Researchers are trying to elucidate the pathogenesis of brucellosis from molecular level.Besides,there are some new clinical manifestations of brucellosis,such as involving one or multiple organs.Diagnostic,therapeutic,and prophylactic methods for brucellosis have also advanced.The review summarizes advances on the pathogenesis,new clinical features and management of brucellosis.