CAJ | 학술논문

当前恶性胶质瘤的诊断主要依靠影像学方法,以病理学检测确定肿瘤分期及恶性度.因为传统的手术、放疗和化疗的治疗方案效果不理想,近年来以胶质瘤相关分子标志物进行鉴别分类并评估其预后成为研究热点.肿瘤标志物在监测肿瘤的复发与转移,临床诊断与治疗等方面具有很高的应用价值,同时为研究肿瘤的发生与发展机制提供了新的方法.
당전악성효질류적진단주요의고영상학방법,이병이학검측학정종류분기급악성도.인위전통적수술、방료화화료적치료방안효과불이상,근년래이효질류상관분자표지물진행감별분류병평고기예후성위연구열점.종류표지물재감측종류적복발여전이,림상진단여치료등방면구유흔고적응용개치,동시위연구종류적발생여발전궤제제공료신적방법.
Until recently,treatment decisions regarding malignant gliomas began with establishing diagnosis by standard imaging methods and determined tumor stage and grade by histopathology.Because the treatment effect of traditional surgery,radiotherapy and chemotherapy is not ideal,biomarkers researches to improve glioma subclassification and prognostic evaluation have become a hot spot.Tumor biomarkers have the very high application value in monitoring tumor recurrence and metastasis,helping clinical diagnosis and treatment,which also apply a new method to explore the mechanism of tumorigenesis and development.