CAJ | 학술논문

背景利多卡因作为酰胺类局部麻醉药,常用于预防罗库溴铵引发的静脉注射痛,可能机制为阻断外周神经细胞膜电压门控Na+通道,抑制Na+内流,产生膜稳定作用,并阻断痛觉传导通路,最终缓解注射痛.目的本文拟对利多卡因预防罗库溴铵静脉注射痛的研究进展进行综述,为该药在临床工作中的应用提供参考. 内容本文分别从作用机制以及同其他药物比较两个方面,综述利多卡因预防罗库溴铵注射痛的效果.趋向利多卡因作为经典局部麻醉药之一,其在临床麻醉中具有越来越广泛的用途.
배경 리다잡인작위선알류국부마취약,상용우예방라고추안인발적정맥주사통,가능궤제위조단외주신경세포막전압문공Na+통도,억제Na+내류,산생막은정작용,병조단통각전도통로,최종완해주사통.목적 본문의대리다잡인예방라고추안정맥주사통적연구진전진행종술,위해약재림상공작중적응용제공삼고. 내용 본문분별종작용궤제이급동기타약물비교량개방면,종술리다잡인예방라고추안주사통적효과.추향 리다잡인작위경전국부마취약지일,기재림상마취중구유월래월엄범적용도.
Background Lidocaine,an amide local anesthetic,is often used in the prevention of injection pain induced by rocuronium.The possible mechanisms are that lidocaine can block the peripheral nerve cell membrane voltage-gated sodium channels,inhibit influx of sodium,and have membrane stabilizing action.Objective This paper intends to review the progress of lidocaine in the prevention of injection pain caused by rocuronium.Content From the mechanism of action and the comparison with other drugs,we reviewed the effects of lidocaine in the prevention of rocuronium-induced injection pain.Trend As one of the classic local anesthetics,the clinical application of lidocaine is quite promising in anesthesia.