国际麻醉学与复苏杂志
國際痳醉學與複囌雜誌
국제마취학여복소잡지
INTERNATIONAL JOURNAL OF ANESTHESIOLOGY AND RESUSCITATION
2014年
3期
246-249
,共4页
氨基酸%麻醉%围手术麻醉期%代谢%营养支持%快速康复外科
氨基痠%痳醉%圍手術痳醉期%代謝%營養支持%快速康複外科
안기산%마취%위수술마취기%대사%영양지지%쾌속강복외과
Amino acid%Anesthesia%Perioperative period%Metabolism%Nutritional support%Fast track surgery
背景 围手术麻醉期的应激反应不利于患者的术后恢复,这与正在快速发展的快速康复外科(fast track surgery,FTS)理念相背离.营养支持是FTS的一个重要策略,输注氨基酸作为围手术麻醉期营养支持的有效方式已有较多临床和基础研究. 目的 探讨围手术麻醉期输注氨基酸对机体体温和营养物质代谢的影响. 内容 氨基酸通过其营养物热效应(nutrient induced thermogenesis,NIT)为围手术麻醉期患者提供了保温作用,并通过多种途径抑制脂肪动员和蛋白分解,促进蛋白合成,但可能加速血糖的升高. 趋向 把握围手术麻醉期输注氨基酸的时机和剂量,使这一FTS的策略得到优化.
揹景 圍手術痳醉期的應激反應不利于患者的術後恢複,這與正在快速髮展的快速康複外科(fast track surgery,FTS)理唸相揹離.營養支持是FTS的一箇重要策略,輸註氨基痠作為圍手術痳醉期營養支持的有效方式已有較多臨床和基礎研究. 目的 探討圍手術痳醉期輸註氨基痠對機體體溫和營養物質代謝的影響. 內容 氨基痠通過其營養物熱效應(nutrient induced thermogenesis,NIT)為圍手術痳醉期患者提供瞭保溫作用,併通過多種途徑抑製脂肪動員和蛋白分解,促進蛋白閤成,但可能加速血糖的升高. 趨嚮 把握圍手術痳醉期輸註氨基痠的時機和劑量,使這一FTS的策略得到優化.
배경 위수술마취기적응격반응불리우환자적술후회복,저여정재쾌속발전적쾌속강복외과(fast track surgery,FTS)이념상배리.영양지지시FTS적일개중요책략,수주안기산작위위수술마취기영양지지적유효방식이유교다림상화기출연구. 목적 탐토위수술마취기수주안기산대궤체체온화영양물질대사적영향. 내용 안기산통과기영양물열효응(nutrient induced thermogenesis,NIT)위위수술마취기환자제공료보온작용,병통과다충도경억제지방동원화단백분해,촉진단백합성,단가능가속혈당적승고. 추향 파악위수술마취기수주안기산적시궤화제량,사저일FTS적책략득도우화.
Background The perioperative period stress response is not conducive to the patient's postoperative recovery.It goes against the fast track surgery (FTS),which is rapidly developing recently.Nutritional support is an important strategy of FTS,and there are already many clinical and basic studies which confirm that perioperative amino acid infusion is an effective mean of nutritional support.Objective This review will discuss the influence of perioperative amino acids infusion to the body temperature and metabolism.Content Amino acid infusion alleviates hypothermia via nutrient induced thermogenesis (NIT),and can inhibit fat mobilization and muscle protein breakdown,promote protein synthesis,while accelerate the increase of blood glucose concentration.Trend It is an optimical strategy for FTS to explore appropriate time and dose of perioperative amino acids infusion.
