国际内分泌代谢杂志
國際內分泌代謝雜誌
국제내분비대사잡지
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2013年
3期
170-172
,共3页
张道文%徐书杭%刘超%蔡可英
張道文%徐書杭%劉超%蔡可英
장도문%서서항%류초%채가영
妊娠%甲状腺自身免疫%妊娠结局
妊娠%甲狀腺自身免疫%妊娠結跼
임신%갑상선자신면역%임신결국
Pregnancy%Thyroid autoimmunity%Pregnant outcome
自身免疫性甲状腺炎(AIT)的发病受遗传、环境等多重因素影响,其在育龄期女性中的患病率颇高,可增加孕早期流产、早产、死胎、辅助生殖技术(ART)时流产等不良妊娠结局及低体重儿的患病率,其可能与免疫异常、甲状腺功能紊乱以及孕妇高龄等因素有关.其治疗措施主要包括免疫调节、甲状腺功能干预,二者效果如何仍待进一步研究.
自身免疫性甲狀腺炎(AIT)的髮病受遺傳、環境等多重因素影響,其在育齡期女性中的患病率頗高,可增加孕早期流產、早產、死胎、輔助生殖技術(ART)時流產等不良妊娠結跼及低體重兒的患病率,其可能與免疫異常、甲狀腺功能紊亂以及孕婦高齡等因素有關.其治療措施主要包括免疫調節、甲狀腺功能榦預,二者效果如何仍待進一步研究.
자신면역성갑상선염(AIT)적발병수유전、배경등다중인소영향,기재육령기녀성중적환병솔파고,가증가잉조기유산、조산、사태、보조생식기술(ART)시유산등불량임신결국급저체중인적환병솔,기가능여면역이상、갑상선공능문란이급잉부고령등인소유관.기치료조시주요포괄면역조절、갑상선공능간예,이자효과여하잉대진일보연구.
A mixture of genetic and environmental factors act in the cause of autoimmunity thyroiditis(AIT),and women of reproductive age have a high morbidity of it.AIT may increase the incidence of abortion in first trimester,premature birth,stillbirth,abortion of assisted reproductive technology and low birth weight infants.Immune disorder,thyroid function disorder,aging might be associated with the poor pregnant outcome.Therefore,immune regulation,thyroid function intervention can be used to deal with it.However,more research about the effectiveness is still needed.