CAJ | 학술논문

红细胞生成素(erythropoietin,EPO)属于细胞因子类,在外周血液循环中主要促进红细胞生成.基础研究显示,EPO可通过多种机制减轻缺血性脑损伤,但同时有许多问题未能解决;另外,EPO的2项临床试验结果也很不一致.文章对EPO研究中存在的问题进行了综述.
홍세포생성소(erythropoietin,EPO)속우세포인자류,재외주혈액순배중주요촉진홍세포생성.기출연구현시,EPO가통과다충궤제감경결혈성뇌손상,단동시유허다문제미능해결;령외,EPO적2항림상시험결과야흔불일치.문장대EPO연구중존재적문제진행료종술.
Erythropoietin (EPO) belongs to cytokines.It mainly promotes erythropoiesis in the peripheral blood circulation.Fundamental research shows that EPO can reduce cerebral ischemic injury through a variety of mechanisms,but at the same time,there are many unsolved problems.In addition,the two clinical trial outcomes are also very inconsistent.This article reviews the problems in EPO research.