CAJ | 학술논문

抵抗素是一种新近发现的多肽类激素.研究显示,抵抗素能通过促进血管内皮细胞炎症反应和黏附、巨噬细胞向泡沫细胞转化、血管平滑肌细胞增殖和迁移、增加斑块不稳定性以及促进糖类和脂质代谢紊乱等,与动脉粥样硬化密切相关.抵抗素能促进缺血性脑血管病的发生和发展,有可能成为潜在的生物学标记物和干预靶点.
저항소시일충신근발현적다태류격소.연구현시,저항소능통과촉진혈관내피세포염증반응화점부、거서세포향포말세포전화、혈관평활기세포증식화천이、증가반괴불은정성이급촉진당류화지질대사문란등,여동맥죽양경화밀절상관.저항소능촉진결혈성뇌혈관병적발생화발전,유가능성위잠재적생물학표기물화간예파점.
Resistin is a recently discovered polypeptide hormone.Studies have shown that resistin is closely associated with atherosclerosis by promoting inflammatory response and adhesion of vascular endothelial cells,transformation from macrophages to foam cells,vascular smooth muscle cell proliferation and migration,increasing plaque instability,as well as promoting carbohydrate and lipid metabolism disorders,etc.Resistin can promote the occurrence and development of ischemic cerebrovascular disease.It may become a potential biological marker and intervention target.