国际脑血管病杂志
國際腦血管病雜誌
국제뇌혈관병잡지
INTERNATIONAL JOURNAL OF CEREBROVASCULAR DISEASES
2014年
4期
312-315
,共4页
王浩%蔺慕会%徐佳亮%陈晓虹
王浩%藺慕會%徐佳亮%陳曉虹
왕호%린모회%서가량%진효홍
脑缺血%星形胶质细胞%缝隙连接%连接蛋白43
腦缺血%星形膠質細胞%縫隙連接%連接蛋白43
뇌결혈%성형효질세포%봉극련접%련접단백43
Brain Ischemia%Astrocytes%Gap Junctions%Connexin 43
研究表明,星形胶质细胞缝隙连接(gap junction,GJ)在缺血性脑损伤中起着重要作用,因此GJ可能会有望成为治疗缺血性脑损伤的新靶点.近年来,虽然对星形胶质细胞GJ与缺血性脑损伤的关系进行了广泛研究,但结论并不一致.文章对GJ的结构、分布、功能及其与缺血性脑损伤相关的研究进展进行了综述.
研究錶明,星形膠質細胞縫隙連接(gap junction,GJ)在缺血性腦損傷中起著重要作用,因此GJ可能會有望成為治療缺血性腦損傷的新靶點.近年來,雖然對星形膠質細胞GJ與缺血性腦損傷的關繫進行瞭廣汎研究,但結論併不一緻.文章對GJ的結構、分佈、功能及其與缺血性腦損傷相關的研究進展進行瞭綜述.
연구표명,성형효질세포봉극련접(gap junction,GJ)재결혈성뇌손상중기착중요작용,인차GJ가능회유망성위치료결혈성뇌손상적신파점.근년래,수연대성형효질세포GJ여결혈성뇌손상적관계진행료엄범연구,단결론병불일치.문장대GJ적결구、분포、공능급기여결혈성뇌손상상관적연구진전진행료종술.
Studies have shown that gap junction (GJ) of astrocytes plays an important role in ischemic brain injury.Therefore,GJ may become a new target for the treatment of ischemic brain injury.In recent years,although the relationship between GJ of astrocytes and ischemic brain injury has been extensively studied,the conclusions are not consistent.This article reviews the structure,distribution,function of GJ,and its research progress related ischemic brain injury.