CAJ | 학술논문

目的探讨三乙醇胺乳膏治疗皮肤慢性溃疡的疗效和安全性.方法 38例皮肤慢性溃疡的患者分为两组,治疗组21例和对照组17例,治疗组在清创和换药的基础上待创面表面清洁后外敷厚层三乙醇胺乳膏,对照组仅用常规清创和换药.结果治疗组21例中痊愈18例,占85.71％,显效2例,占9.52％,好转1例,占4.76％,总有效率为95.24％;对照组17例中痊愈8例,占47.06％,显效2例,占11.76％,好转5例,占29.41％,总有效率为58.82％,两组比较差异有统计学意义(P＜0.05).治疗组者肉芽组织出现时间、皮肤溃疡愈合时间均优于对照组,两组比较差异有统计学意义(P＜0.01).结论三乙醇胺治疗皮肤慢性溃疡疗效确切,患者耐受性好.
목적 탐토삼을순알유고치료피부만성궤양적료효화안전성.방법 38례피부만성궤양적환자분위량조,치료조21례화대조조17례,치료조재청창화환약적기출상대창면표면청길후외부후층삼을순알유고,대조조부용상규청창화환약.결과 치료조21례중전유18례,점85.71％,현효2례,점9.52％,호전1례,점4.76％,총유효솔위95.24％;대조조17례중전유8례,점47.06％,현효2례,점11.76％,호전5례,점29.41％,총유효솔위58.82％,량조비교차이유통계학의의(P＜0.05).치료조자육아조직출현시간、피부궤양유합시간균우우대조조,량조비교차이유통계학의의(P＜0.01).결론 삼을순알치료피부만성궤양료효학절,환자내수성호.
Objective To assess the efficacy and safety of triethanolamine cream for the treament of chronic skin ulcer.Methods Thirty-eight patients with chronic skin ulcer were classified into the test group and control group.The control group was routinely treated with debridement and dressing,while the test group was topically treated with triethanolamine cream besides debredement and dressing.Results After 8 weeks of treatment,the lesions healed in 18 (85.71％) patients in the test group and 8 (47.06％) patients in the control group,markedly improved in 2 (9.52％) patients in the test group and 2 (11.76％) patients in the control group,improved in 1 (4.76％) patient in the test group and 5 (29.41％) patients in the control group.The total response rate was significantly different between the test group and control group (95.24％ vs.58.82％,x2 =6.497,P ＜ 0.05).Both the time required for granulation tissue to generate and that for skin ulcer to heal were shorter in the test group than in the control group (both P ＜ 0.01).Conclusion Triethanolamine cream is a safe,effective,and well-tolerated treatment option for chronic skin ulcer.