CAJ | 학술논문

目的探讨胸腺瘤Masaoka分期及WHO分型与重症肌无力关系的临床意义.方法回顾性分析2004年12月-2009年9月胸腺瘤切除标本及完整病例81例,运用统计学软件分析胸腺瘤Masaoka分期及WHO分型与重症肌无力的关系.结果胸腺瘤Masaoka临床不同分期之间合并重症肌无力的发病率差异有统计学意义(P＜0.05).胸腺瘤WHO组织学不同分型之间合并重症肌无力的发病率差异有统计学意义(P＜0.05).胸腺瘤Masaoka临床分期与WHO组织学分型之间的关系差异有统计学意义(P＜0.05,κ =0.580,C=0.503).结论胸腺瘤Masaoka临床分期与合并重症肌无力有一定的关系,胸腺瘤WHO组织学分型与合并重症肌无力也有一定的关系,同时WHO分型在一定程度上反映了Masaoka临床分期,因而在一定程度上可以作为评价患者预后的重要指标之一.
목적 탐토흉선류Masaoka분기급WHO분형여중증기무력관계적림상의의.방법 회고성분석2004년12월-2009년9월흉선류절제표본급완정병례81례,운용통계학연건분석흉선류Masaoka분기급WHO분형여중증기무력적관계.결과 흉선류Masaoka림상불동분기지간합병중증기무력적발병솔차이유통계학의의(P＜0.05).흉선류WHO조직학불동분형지간합병중증기무력적발병솔차이유통계학의의(P＜0.05).흉선류Masaoka림상분기여WHO조직학분형지간적관계차이유통계학의의(P＜0.05,κ =0.580,C=0.503).결론 흉선류Masaoka림상분기여합병중증기무력유일정적관계,흉선류WHO조직학분형여합병중증기무력야유일정적관계,동시WHO분형재일정정도상반영료Masaoka림상분기,인이재일정정도상가이작위평개환자예후적중요지표지일.
Objective To investigate the clinical significance of relationship between the myasthenia gravis and WHO histological types & Masaoka clinical stage of thymoma.Methods Retrospective analysis of resection specimen in thymoma and complete medical records in 81 cases from December 2004 to September 2009,using the analysis of statistical software between myasthenia gravis and both thymoma Masaoka clinical stages & the WHO histological types.Results The difference of merger with MG of thymoma Masaoka among different clinical stages was statistically significant (P ＜ 0.05).The difference of merger with MG Thymoma WHO among different histological types was statistically significant (P ＜ 0.05).The difference of thymoma Masaoka between the WHO histological type and Masaoka clinical stages was statistically significant (P ＜ 0.05,kappa =0.580,C =0.503).Conclusions There are some relationships between thymoma Masaoka clinical stages and MG,so had some relationships between thymoma WHO histological types and MG.At the same time,the thymoma WHO histological types reflects the Masaoka clinical stages in a certain extent.This relationship would be used as one of the important indicators to evaluate the prognosis of patients at some extent.