国际外科学杂志
國際外科學雜誌
국제외과학잡지
INTERNATIONAL JOURNAL OF SURGERY
2014年
10期
677-679,封3
,共4页
金鑫%吕少诚%刘飞德%傅庭焕%裴利娟%史宪杰
金鑫%呂少誠%劉飛德%傅庭煥%裴利娟%史憲傑
금흠%려소성%류비덕%부정환%배리연%사헌걸
胰腺肿瘤%导管消融术%随访研究%回顾性研究
胰腺腫瘤%導管消融術%隨訪研究%迴顧性研究
이선종류%도관소융술%수방연구%회고성연구
Pancreatic neoplasms%Catheter ablation%Follow-up studies%Retrospective studies
目的 探讨射频消融术在晚期胰腺癌患者治疗中的效果及中远期随访情况.方法 回顾性分析304医院2008年1月-2012年12月行射频消融术治疗晚期胰腺癌28例患者的围手术期临床资料,并将该组资料与同期行姑息性手术治疗的140例晚期胰腺癌患者的临床资料进行对比分析,并对两组患者术后中远期的随访情况进行对比分析.结果 28例行射频消融术的晚期胰腺癌患者,肿瘤的平均最大直径为(4.8±1.6) cm,术中平均射频消融时间为(17.7±4.3) min,术后无胰瘘患者,无围手术期死亡患者,围手术期疼痛缓解率为88.9％.23例患者获得随访,随访率为82.1％,其1个月、6个月、1年的生存率分别为95.7％、65.2％、38.2％,平均生存时间为(14.6±2.2)个月,优于同期行姑息性手术治疗的晚期胰腺癌患者(97.4％、45.3％、19.1％,P=0.0306).结论 对于不能行根治性切除的晚期胰腺癌患者,射频消融术是一种有效的治疗手段,能相对延长患者的生存时间.
目的 探討射頻消融術在晚期胰腺癌患者治療中的效果及中遠期隨訪情況.方法 迴顧性分析304醫院2008年1月-2012年12月行射頻消融術治療晚期胰腺癌28例患者的圍手術期臨床資料,併將該組資料與同期行姑息性手術治療的140例晚期胰腺癌患者的臨床資料進行對比分析,併對兩組患者術後中遠期的隨訪情況進行對比分析.結果 28例行射頻消融術的晚期胰腺癌患者,腫瘤的平均最大直徑為(4.8±1.6) cm,術中平均射頻消融時間為(17.7±4.3) min,術後無胰瘺患者,無圍手術期死亡患者,圍手術期疼痛緩解率為88.9％.23例患者穫得隨訪,隨訪率為82.1％,其1箇月、6箇月、1年的生存率分彆為95.7％、65.2％、38.2％,平均生存時間為(14.6±2.2)箇月,優于同期行姑息性手術治療的晚期胰腺癌患者(97.4％、45.3％、19.1％,P=0.0306).結論 對于不能行根治性切除的晚期胰腺癌患者,射頻消融術是一種有效的治療手段,能相對延長患者的生存時間.
목적 탐토사빈소융술재만기이선암환자치료중적효과급중원기수방정황.방법 회고성분석304의원2008년1월-2012년12월행사빈소융술치료만기이선암28례환자적위수술기림상자료,병장해조자료여동기행고식성수술치료적140례만기이선암환자적림상자료진행대비분석,병대량조환자술후중원기적수방정황진행대비분석.결과 28례행사빈소융술적만기이선암환자,종류적평균최대직경위(4.8±1.6) cm,술중평균사빈소융시간위(17.7±4.3) min,술후무이루환자,무위수술기사망환자,위수술기동통완해솔위88.9％.23례환자획득수방,수방솔위82.1％,기1개월、6개월、1년적생존솔분별위95.7％、65.2％、38.2％,평균생존시간위(14.6±2.2)개월,우우동기행고식성수술치료적만기이선암환자(97.4％、45.3％、19.1％,P=0.0306).결론 대우불능행근치성절제적만기이선암환자,사빈소융술시일충유효적치료수단,능상대연장환자적생존시간.
Objective To explore the clinical effect of radio-frequency ablation in the treatment of advanced pancreatic cancer.Methods Retrospectively analyzed the clinical data of 28 cases of radio-frequency ablation in the treatment of advanced pancreatic cance between January 2008 and December 2012 in 304 hospital.And choosed made 140 cases patients who only underwent the conservative treatment as the control group at the same period.Then compared the data of two groups patients.Results The mean tumor diameter was (4.8 ± 1.6) cm.The average radio-frequency time was (17.7 ± 4.3) minutes.There was no patient occurred of pancreatic fistula or postoperative bleeding,and no patient dead.Peri-operation pain relief rate was 88.9％.Twenty-three patients were followed up,and the follow up rate was 82.1％.The patients' survival rate who underwent radio-frequency ablation of 1 month,6 months and 1 year were 95.7％,65.2％ and 38.2％.The average survival time was (14.6 ± 2.2) months.And the data was significantly higher than that of the control group patients (97.4％,45.3％,19.1％,P =0.0306).Conclusions The radio-frequency ablation was one of an effective treatment method for the advanced pancreatic cancer patients.It can prolong the survival time of pancreatic cancer patients and alleviate the patient's pain.
