国际外科学杂志
國際外科學雜誌
국제외과학잡지
INTERNATIONAL JOURNAL OF SURGERY
2014年
10期
688-690
,共3页
黄疸,梗阻性%诊断,鉴别%血清,B7-H3
黃疸,梗阻性%診斷,鑒彆%血清,B7-H3
황달,경조성%진단,감별%혈청,B7-H3
Jaundice,obstructive%Diagnosis,differential%Serum,B7-H3
目的 通过检测良恶性梗阻性黄疸患者术前及术后血清B7-H3水平,了解其在梗阻性黄疸良恶性鉴别诊断方面的临床应用价值.方法 采集良性梗阻性黄疸32例及恶性梗阻性黄疸患者28例手术治疗前后的血清,通过酶联免疫吸附试验检测血清B7-H3浓度.结果 恶性梗阻性黄疸组血清B7-H3水平明显高于良性组(9334.57±1009.57) pg/mL vs(4450.81±406.92) pg/mL,差异具有显著的统计学意义(P＜0.01);良恶性梗阻性黄疸组术后血清B7-H3水平较术前降低(2531.03 ±415.64) pg/mL vs(4450.81±406.92)pg/mL,(5833.00 ±2190.87) pg/mL vs(9334.57±1009.57) pg/mL,差异具有显著的统计学意义(P＜0.01).结论 血清B7-H3参与机体炎症及肿瘤免疫应答,可用于梗阻性黄疸良恶性病因鉴别诊断.
目的 通過檢測良噁性梗阻性黃疸患者術前及術後血清B7-H3水平,瞭解其在梗阻性黃疸良噁性鑒彆診斷方麵的臨床應用價值.方法 採集良性梗阻性黃疸32例及噁性梗阻性黃疸患者28例手術治療前後的血清,通過酶聯免疫吸附試驗檢測血清B7-H3濃度.結果 噁性梗阻性黃疸組血清B7-H3水平明顯高于良性組(9334.57±1009.57) pg/mL vs(4450.81±406.92) pg/mL,差異具有顯著的統計學意義(P＜0.01);良噁性梗阻性黃疸組術後血清B7-H3水平較術前降低(2531.03 ±415.64) pg/mL vs(4450.81±406.92)pg/mL,(5833.00 ±2190.87) pg/mL vs(9334.57±1009.57) pg/mL,差異具有顯著的統計學意義(P＜0.01).結論 血清B7-H3參與機體炎癥及腫瘤免疫應答,可用于梗阻性黃疸良噁性病因鑒彆診斷.
목적 통과검측량악성경조성황달환자술전급술후혈청B7-H3수평,료해기재경조성황달량악성감별진단방면적림상응용개치.방법 채집량성경조성황달32례급악성경조성황달환자28례수술치료전후적혈청,통과매련면역흡부시험검측혈청B7-H3농도.결과 악성경조성황달조혈청B7-H3수평명현고우량성조(9334.57±1009.57) pg/mL vs(4450.81±406.92) pg/mL,차이구유현저적통계학의의(P＜0.01);량악성경조성황달조술후혈청B7-H3수평교술전강저(2531.03 ±415.64) pg/mL vs(4450.81±406.92)pg/mL,(5833.00 ±2190.87) pg/mL vs(9334.57±1009.57) pg/mL,차이구유현저적통계학의의(P＜0.01).결론 혈청B7-H3삼여궤체염증급종류면역응답,가용우경조성황달량악성병인감별진단.
Objective To investigated the significance of serum B7-H3 in differential diagnosis of patients with benign and malignant obstructive jaundice.Methods The B7-H3 levels in 60 patients with obstructive jaundice who were divided into benign (32 patients) and malignant (28 patients) obstructive jaundice group were tested by enzyme-linked immunosorbent assay before and after operation.Results The serum B7-H3 levels of malignant obstructive jaundice group were significantly higher than that of benign group (9334.57 ± 1009.57) pg/mL vs (4450.81 ± 406.92) pg/mL,(P ＜ 0.01).The B7-H3 levels of benign and malignant obstructive jaundice group after operation were significantly lower than those before operation (2531.03 ± 415.64) pg/mL vs (4450.81 ±406.92) pg/mL,(5833.00 ± 2190.87) pg/mL vs (9334.57±1009.57) pg/mL,(P＜0.01).Conclusion B7-H3 participate in the inflammatory immune and tumor immune response,The serum B7-H3 can be used as differential diagnosis index of benign and malignant obstructive jaundice.
