CAJ | 학술논문

目的采用红外光谱法对草乌原药材、不同程度水炮制品种提取物进行分析,观察草乌炮制过程中主要毒性成分的变化.方法采用傅立叶变换红外光谱法,研究草乌原药材、不同程度水炮制品种的红外光谱特征.结果 ①由乌头碱和次乌头碱的红外谱图得知1717 cm-1、1727 cm-1和1711 cm-1是C=O伸缩振动峰,是双酯型生物碱的特征峰;②所有的水泡样品虽吸收峰有一定变化,但仍存在双酯型生物碱吸收峰,说明水解不完全；③水煮草乌炮制法,在水煮样品中双酯型生物碱的吸收峰发生位移.结论草乌中双酯型生物碱与水泡时间的长短呈正相关.
목적 채용홍외광보법대초오원약재、불동정도수포제품충제취물진행분석,관찰초오포제과정중주요독성성분적변화.방법 채용부립협변환홍외광보법,연구초오원약재、불동정도수포제품충적홍외광보특정.결과 ①유오두감화차오두감적홍외보도득지1717 cm-1、1727 cm-1화1711 cm-1시C=O신축진동봉,시쌍지형생물감적특정봉;②소유적수포양품수흡수봉유일정변화,단잉존재쌍지형생물감흡수봉,설명수해불완전；③수자초오포제법,재수자양품중쌍지형생물감적흡수봉발생위이.결론 초오중쌍지형생물감여수포시간적장단정정상관.
Objective Infrared spectroscopy was used to study on both raw material and different degree water processing varieties extract of Radix Aconiti kusnezoffii,to observe the changes of main toxic components in processing,and thus to improve the quality of Radix Aconiti kusnezoffii processed products.Methods Fu Liye transform infrared spectroscopy was adopted to study the infrared spectrum characteristic of raw materials and different degree water processing varieties of.Radix Aconiti kusnezoffii.Results ①Aconitine and hypaconitine infrared spectrum showed that 1717 cm-1,1727 cm-1 and 1711 cm-1 is the C=O stretching vibration peak.It is a diester alkaloids characteristic peaks; ② although absorption peak of all vesicular samples had a certain change,it still existed diester alkaloids absorption peak,indicating the incomplete hydrolysis; ③ boiled aconite processing methods demonstrated diester alkaloids absorption peak shift in the water sample.Conclusion Diester alkaloids in Radix Aconiti kusnezoffii shows a positive relation with its time soaked in water.