国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2013年
8期
689-691
,共3页
肠易激综合征%寒热错杂%乌梅丸
腸易激綜閤徵%寒熱錯雜%烏梅汍
장역격종합정%한열착잡%오매환
Irritable bowel syndrome%Cold-heat complex%Wumei Pill
目的 观察乌梅丸治疗寒热错杂型肠易激综合征(腹泻型)的临床疗效.方法 收集2009年1月至2011年12月中国中医科学院广安门医院门诊患者,对符合中医寒热错杂证诊断标准、西医肠易激综合征(腹泻型)诊断标准的46例患者,均予乌梅丸加减方治疗,分别观察大便次数、大便性状、腹痛不适、肠鸣、畏寒怕冷5种主要症状.并对治疗前、治疗后1周、2周及4周进行症状积分评价.结果 治疗后1周、2周及4周时患者总有效率分别为58.70％ (27/46)、84.78％ (39/46)、97.83％ (45/46),其中总有效率治疗后2周与治疗后1周比较,治疗后4周与治疗后2周比较,治疗后4周与治疗后1周比较,差异均有统计学意义(治疗2周与治疗1周比x2=8.571;治疗4周与治疗2周比x2=16.426;治疗4周与治疗1周比x2=35.622,P均＜0.05).治疗后4周大便次数、大便性状、腹痛不适、肠鸣、畏寒怕冷有效率分别为82.05％ (32/39)、95.56％ (43/45)、92.86％ (39/42)、85.71％(18/21)、64.29％ (27/42),与治疗后1周比较,差异有统计学意义(大便次数x2=7.123、大便性状x2=13.611、腹痛不适x2=7.721、肠鸣x2=10.096、畏寒怕冷x2=10.769,P均＜0.05).结论 乌梅丸治疗寒热错杂型肠易激综合征(腹泻型)疗效确定.
目的 觀察烏梅汍治療寒熱錯雜型腸易激綜閤徵(腹瀉型)的臨床療效.方法 收集2009年1月至2011年12月中國中醫科學院廣安門醫院門診患者,對符閤中醫寒熱錯雜證診斷標準、西醫腸易激綜閤徵(腹瀉型)診斷標準的46例患者,均予烏梅汍加減方治療,分彆觀察大便次數、大便性狀、腹痛不適、腸鳴、畏寒怕冷5種主要癥狀.併對治療前、治療後1週、2週及4週進行癥狀積分評價.結果 治療後1週、2週及4週時患者總有效率分彆為58.70％ (27/46)、84.78％ (39/46)、97.83％ (45/46),其中總有效率治療後2週與治療後1週比較,治療後4週與治療後2週比較,治療後4週與治療後1週比較,差異均有統計學意義(治療2週與治療1週比x2=8.571;治療4週與治療2週比x2=16.426;治療4週與治療1週比x2=35.622,P均＜0.05).治療後4週大便次數、大便性狀、腹痛不適、腸鳴、畏寒怕冷有效率分彆為82.05％ (32/39)、95.56％ (43/45)、92.86％ (39/42)、85.71％(18/21)、64.29％ (27/42),與治療後1週比較,差異有統計學意義(大便次數x2=7.123、大便性狀x2=13.611、腹痛不適x2=7.721、腸鳴x2=10.096、畏寒怕冷x2=10.769,P均＜0.05).結論 烏梅汍治療寒熱錯雜型腸易激綜閤徵(腹瀉型)療效確定.
목적 관찰오매환치료한열착잡형장역격종합정(복사형)적림상료효.방법 수집2009년1월지2011년12월중국중의과학원엄안문의원문진환자,대부합중의한열착잡증진단표준、서의장역격종합정(복사형)진단표준적46례환자,균여오매환가감방치료,분별관찰대편차수、대편성상、복통불괄、장명、외한파랭5충주요증상.병대치료전、치료후1주、2주급4주진행증상적분평개.결과 치료후1주、2주급4주시환자총유효솔분별위58.70％ (27/46)、84.78％ (39/46)、97.83％ (45/46),기중총유효솔치료후2주여치료후1주비교,치료후4주여치료후2주비교,치료후4주여치료후1주비교,차이균유통계학의의(치료2주여치료1주비x2=8.571;치료4주여치료2주비x2=16.426;치료4주여치료1주비x2=35.622,P균＜0.05).치료후4주대편차수、대편성상、복통불괄、장명、외한파랭유효솔분별위82.05％ (32/39)、95.56％ (43/45)、92.86％ (39/42)、85.71％(18/21)、64.29％ (27/42),여치료후1주비교,차이유통계학의의(대편차수x2=7.123、대편성상x2=13.611、복통불괄x2=7.721、장명x2=10.096、외한파랭x2=10.769,P균＜0.05).결론 오매환치료한열착잡형장역격종합정(복사형)료효학정.
Objective To observe the clinical curative effect of Wumei Pill in the treatment of cold-heat complex diarrhea-predominant irritable bowel syndrome.Methods Modified Wumei Pill was adopted to treat 46 cases of cold-heat complex diarrhea predominant irritable bowel syndrome.Five main symptoms of stool frequency,stool shape and properties,abdominal pain and discomfort,bowel gurgling,vulnerable to the cold were observed.The symptom scores before the treatment and 1 week,2 weeks and 4 weeks after the treatment were evaluated.Results After the treatment of 1 week,2 weeks and 4 weeks,the overall efficiency was 58.70％(27/46),84.78％(39/46),and 97.83％(45/46) respectively,and there were significant differences in curative effect between the different treatment courses (between treatment of 2 weeks and 1 weekx2＝8.571,between treatment of 4 weeks and 2 weekx2=16.426,between treatment of 4 weeks and 1 week x2=35.622).Effective rate of symptoms after 4 weeks treatment were respectively:stool frequency 82.05％ (32/39),stool shape and properties 95.56％ (43/45),abdominal pain and discomfort 92.86％ (39/42),bowel gurgling 85.71％ (18/21),vulnerable to the cold 64.29％ (27/42),and there was obvious differences in effective percentage of five kinds of symptoms between treatment of 4 weeks and 1 week (Stool frequency x2 =7.123、stool shape and properties x2 =13.611、abdominal pain or discomfort x2 =7.721、bowel gurgling x2=10.096、vulnerable to the cold x2=10.769).Conclusion.The clinical effect of Wumei Pill for the treatment of cold-heat complex diarrhea predominant irritable bowel syndrome was defined.
