国际中医中药杂志
國際中醫中藥雜誌
국제중의중약잡지
INTERNATIONAL JOURNAL OF TRIDITIONAL CHINESE MEDICINE
2013年
8期
692-694
,共3页
李光善%任志雄%郑亚琳%黄达%李鸣镝
李光善%任誌雄%鄭亞琳%黃達%李鳴鏑
리광선%임지웅%정아림%황체%리명적
升陷汤%左甲状腺素钠片%甲状腺癌%甲状腺功能减退
升陷湯%左甲狀腺素鈉片%甲狀腺癌%甲狀腺功能減退
승함탕%좌갑상선소납편%갑상선암%갑상선공능감퇴
Shengxian decoction%levothyroxine sodium tablets%Thyroid cancer%Hypothyroidation%Treatment of Chinese medicine
目的 观察升陷汤加减联合左甲状腺素钠片治疗甲状腺癌术后甲状腺功能减退(简称“甲减”)患者的临床疗效.方法 采用随机数字表法将中医辨证符合脾肾两虚证的60例甲状腺癌术后甲减患者随机分为两组,对照组28例采用左甲状腺素钠片常规治疗,治疗组32例在对照组治疗基础上加用升陷汤加减.观察两组患者治疗前后临床疗效、汉密尔顿抑郁量表(HAMD-17)评分等指标的变化.结果 治疗后,治疗组总有效率为87.5％ (28/32)、对照组为64.3％(18/28),两组比较差异有统计学意义(x2=4.499,P＜0.05).治疗组,治疗后HAMD-17总分为(6.8±2.3)分、对照组为(15.8±2.1)分,均较同组治疗前[分别为(19.4±1.45)分、(18.9±1.32)分]改善;且两组治疗后比较,差异有统计学意义(P＜0.01).结论 升陷汤加减联合左甲状腺素钠片治疗甲状腺癌术后甲减有效.
目的 觀察升陷湯加減聯閤左甲狀腺素鈉片治療甲狀腺癌術後甲狀腺功能減退(簡稱“甲減”)患者的臨床療效.方法 採用隨機數字錶法將中醫辨證符閤脾腎兩虛證的60例甲狀腺癌術後甲減患者隨機分為兩組,對照組28例採用左甲狀腺素鈉片常規治療,治療組32例在對照組治療基礎上加用升陷湯加減.觀察兩組患者治療前後臨床療效、漢密爾頓抑鬱量錶(HAMD-17)評分等指標的變化.結果 治療後,治療組總有效率為87.5％ (28/32)、對照組為64.3％(18/28),兩組比較差異有統計學意義(x2=4.499,P＜0.05).治療組,治療後HAMD-17總分為(6.8±2.3)分、對照組為(15.8±2.1)分,均較同組治療前[分彆為(19.4±1.45)分、(18.9±1.32)分]改善;且兩組治療後比較,差異有統計學意義(P＜0.01).結論 升陷湯加減聯閤左甲狀腺素鈉片治療甲狀腺癌術後甲減有效.
목적 관찰승함탕가감연합좌갑상선소납편치료갑상선암술후갑상선공능감퇴(간칭“갑감”)환자적림상료효.방법 채용수궤수자표법장중의변증부합비신량허증적60례갑상선암술후갑감환자수궤분위량조,대조조28례채용좌갑상선소납편상규치료,치료조32례재대조조치료기출상가용승함탕가감.관찰량조환자치료전후림상료효、한밀이돈억욱량표(HAMD-17)평분등지표적변화.결과 치료후,치료조총유효솔위87.5％ (28/32)、대조조위64.3％(18/28),량조비교차이유통계학의의(x2=4.499,P＜0.05).치료조,치료후HAMD-17총분위(6.8±2.3)분、대조조위(15.8±2.1)분,균교동조치료전[분별위(19.4±1.45)분、(18.9±1.32)분]개선;차량조치료후비교,차이유통계학의의(P＜0.01).결론 승함탕가감연합좌갑상선소납편치료갑상선암술후갑감유효.
Objective To observe the clinical effects of modified Shengxian decoction in the treatment of thyroid cancer postoperative hypothyroidism patients.Methods 60 patients of thyroid cancer postoperative hypothyroidism due to deficiency of spleen and kidney were randomly divided into a control group and a treatment group.The control group (28 cases) was by levothyroxine sodium tablets conventional treatment,while the treatment group (32 cases) was treated with Shengxian decoction based on thecontrol group.The changes of the symptom integral and HAMD-17 were observed between two groups before and after treatment.Results After treatment,the total effective rate was 87.5％ in the treatment group and 64.3％ in the control group,the clinical effect of treatment group was significantly better than the control group (x2=4.499,P＜ 0.05).After treatment,the total score of HAMD-17 was 6.8±2.3 in the treatment group and 15.8±2.1 in the control group,both significantly improved than that before the treatment (which were 19.4±1.45 and 18.9± 1.32 respectively).Compared with the control group,the treatment group improved significantly (P＜ 0.01).Conclusion Shengxian decoction plus western medicine has remarkable curative effect in the treatment of thyroid cancer postoperative hypothyroidism,it can improve the depressive state of patients and improve the quality of life.
