中华解剖与临床杂志
中華解剖與臨床雜誌
중화해부여림상잡지
Chinese Journal of Anatomy and Clinics
2014年
1期
33-36
,共4页
梁德志%朱迪%刘远健%谢晨%韦伟
樑德誌%硃迪%劉遠健%謝晨%韋偉
량덕지%주적%류원건%사신%위위
甲状腺乳头状癌%结节性甲状腺肿%能谱%X线计算机%体层摄影术
甲狀腺乳頭狀癌%結節性甲狀腺腫%能譜%X線計算機%體層攝影術
갑상선유두상암%결절성갑상선종%능보%X선계산궤%체층섭영술
Papillary thyroid carcinoma%Goiter%Spectral imaging%X-ray computed%Tomography
目的 利用宝石CT能谱成像技术(GSI)测量甲状腺乳头状癌与结节性甲状腺肿患者非瘤区甲状腺组织内碘含量,并与正常甲状腺内碘含量比较,探索甲状腺碘含量与甲状腺疾病的关系.方法 收集北京大学深圳医院2011年8月-2013年7月接受甲状腺能谱CT检查并经手术病理证实的甲状腺病变患者36例,其中甲状腺乳头状癌18例、结节性甲状腺肿18例.正常甲状腺对照组15例,为怀疑颈部或颈椎疾病进行能谱CT扫描,无甲状腺功能及结构异常.使用GE公司宝石CT(GE Discovery CT750 HD CT)GSI模式扫描,图像采集后用GSI Viewer浏览器处理,在碘基图中对结节性甲状腺肿与甲状腺乳头状癌病变外正常甲状腺组织及正常对照组甲状腺组织进行测量,采用Wilcoxon秩和检验及t检验进行统计学分析并探究其碘含量的分布特点.结果 甲状腺乳头状癌中非瘤区腺体组织与正常甲状腺、结节性甲状腺肿中非瘤区腺体组织与正常甲状腺碘含量两两比较,差异均有统计学意义(P＜0.05),甲状腺乳头状癌中非瘤区腺体组织与结节性甲状腺肿中非瘤区腺体组织的碘含量比较,差异无统计学意义(P＞0.05),甲状腺乳头状癌中非瘤区腺体组织与结节性甲状腺肿中非瘤区腺体组织甲状腺碘含量呈“U”型分布.结论 CT能谱成像技术作为一种新的方法,能够无创性地检测人体甲状腺碘含量,此技术将有助于进一步揭示甲状腺碘含量与甲状腺疾病关系.
目的 利用寶石CT能譜成像技術(GSI)測量甲狀腺乳頭狀癌與結節性甲狀腺腫患者非瘤區甲狀腺組織內碘含量,併與正常甲狀腺內碘含量比較,探索甲狀腺碘含量與甲狀腺疾病的關繫.方法 收集北京大學深圳醫院2011年8月-2013年7月接受甲狀腺能譜CT檢查併經手術病理證實的甲狀腺病變患者36例,其中甲狀腺乳頭狀癌18例、結節性甲狀腺腫18例.正常甲狀腺對照組15例,為懷疑頸部或頸椎疾病進行能譜CT掃描,無甲狀腺功能及結構異常.使用GE公司寶石CT(GE Discovery CT750 HD CT)GSI模式掃描,圖像採集後用GSI Viewer瀏覽器處理,在碘基圖中對結節性甲狀腺腫與甲狀腺乳頭狀癌病變外正常甲狀腺組織及正常對照組甲狀腺組織進行測量,採用Wilcoxon秩和檢驗及t檢驗進行統計學分析併探究其碘含量的分佈特點.結果 甲狀腺乳頭狀癌中非瘤區腺體組織與正常甲狀腺、結節性甲狀腺腫中非瘤區腺體組織與正常甲狀腺碘含量兩兩比較,差異均有統計學意義(P＜0.05),甲狀腺乳頭狀癌中非瘤區腺體組織與結節性甲狀腺腫中非瘤區腺體組織的碘含量比較,差異無統計學意義(P＞0.05),甲狀腺乳頭狀癌中非瘤區腺體組織與結節性甲狀腺腫中非瘤區腺體組織甲狀腺碘含量呈“U”型分佈.結論 CT能譜成像技術作為一種新的方法,能夠無創性地檢測人體甲狀腺碘含量,此技術將有助于進一步揭示甲狀腺碘含量與甲狀腺疾病關繫.
목적 이용보석CT능보성상기술(GSI)측량갑상선유두상암여결절성갑상선종환자비류구갑상선조직내전함량,병여정상갑상선내전함량비교,탐색갑상선전함량여갑상선질병적관계.방법 수집북경대학심수의원2011년8월-2013년7월접수갑상선능보CT검사병경수술병리증실적갑상선병변환자36례,기중갑상선유두상암18례、결절성갑상선종18례.정상갑상선대조조15례,위부의경부혹경추질병진행능보CT소묘,무갑상선공능급결구이상.사용GE공사보석CT(GE Discovery CT750 HD CT)GSI모식소묘,도상채집후용GSI Viewer류람기처리,재전기도중대결절성갑상선종여갑상선유두상암병변외정상갑상선조직급정상대조조갑상선조직진행측량,채용Wilcoxon질화검험급t검험진행통계학분석병탐구기전함량적분포특점.결과 갑상선유두상암중비류구선체조직여정상갑상선、결절성갑상선종중비류구선체조직여정상갑상선전함량량량비교,차이균유통계학의의(P＜0.05),갑상선유두상암중비류구선체조직여결절성갑상선종중비류구선체조직적전함량비교,차이무통계학의의(P＞0.05),갑상선유두상암중비류구선체조직여결절성갑상선종중비류구선체조직갑상선전함량정“U”형분포.결론 CT능보성상기술작위일충신적방법,능구무창성지검측인체갑상선전함량,차기술장유조우진일보게시갑상선전함량여갑상선질병관계.
Objective To explore iodine concentration in non-tumor thyroid tissue of nodular goiter and papillary thyroid carcinoma,and to compare the different values of iodine concentration on normal thyroid with gemstone spectral CT.Methods Thirty-six cases (18 cases of papillary thyroid carcinoma and 18 cases of nodular goiter) with thyroid nodules were collected,nodules of which were all confirmed with surgical pathology in Peking University Shenzhen Hospital from August 2011 to July 2013.As a control group,15 cases with suspected neck or cervical other unease,but normal function and structure of the thyroids were also included in this study.Image processing was performed on GSI Viewer browser to measure the different iodine concentration of thyroid tissue outside the lesion and normal thyroid.Statistical analysis was processed with Wilcoxon rank test and t-test.The distribution characteristics of the iodine concentration were explored as well.Results The differences of iodine concentration values were found between nontumor tissue of papillary thyroid carcinoma and normal thyroid,as well as between non-tumor tissue of nodular goiter and normal thyroid (P ＜ 0.05 in each group).The differences were not found between papillary thyroid carcinoma and nodular goiter (P ＞ 0.05).Iodine concentration of thyroid tissue outside the lesion in nodular goiter and papillary thyroid carcinoma showed " U" type distribution.Conclusions Gemstone spectral CT,as a noninvasive method to detect iodine concentration in thyroid,will be helpful to reveal the relation between iodine concentration and thyroid disease.
