CAJ | 학술논문

目的观察滑槽钉生长棒内固定系统单边固定对幼猪脊柱发育的影响.方法将15只3月龄幼猪采用完全随机化法随机分为3组:A组(5只)为空白对照组,自幼猪后路单侧切开,仅显露单侧椎板;B组(5只)为对照组,同法显露单侧椎板后常规椎弓根钉系统固定;C组(5只)为实验组,同法显露后单侧置入滑槽钉生长棒内固定系统固定.术后3个月应用X线测量T6～10、T10～14椎体的平均高度,T6～10椎间隙的平均高度,以及C组的钛棒上下两端滑动的平均距离.术后3个月时处死实验动物,选取固定节段的椎间盘观察生长板软骨细胞的形态学变化.结果术后3个月,C组T6～10、T10～14椎体的平均高度分别为(26.81±1.70) mm、(27.43±2.92) mm,T6～10椎间隙的平均高度为(2.13±0.17)mm,与A组的(27.13 ±3.31)mm、(27.91±3.03) mm、(2.20±0.14)mm比较,差异均无统计学意义(P值均＞0.05),而与B组的(22.30±2.52)mm、(22.62±2.11)mm、(0.82±0.41)mm比较增加明显,差异均有统计学意义(P值均＜0.05),C组钛棒上下两端滑动平均距离42.7 mm.C组生长板软骨细胞层高度(165.6±1.7) μm与A组(167.2±6.8) μm比较差异无统计学意义(P＞0.05);而与B组(140.4±7.2) μm比较增加明显,差异有统计学意义(P＜0.05).结论滑槽钉生长棒内固定系统单边固定对幼猪脊柱生长发育无明显影响.
목적 관찰활조정생장봉내고정계통단변고정대유저척주발육적영향.방법 장15지3월령유저채용완전수궤화법수궤분위3조:A조(5지)위공백대조조,자유저후로단측절개,부현로단측추판;B조(5지)위대조조,동법현로단측추판후상규추궁근정계통고정;C조(5지)위실험조,동법현로후단측치입활조정생장봉내고정계통고정.술후3개월응용X선측량T6～10、T10～14추체적평균고도,T6～10추간극적평균고도,이급C조적태봉상하량단활동적평균거리.술후3개월시처사실험동물,선취고정절단적추간반관찰생장판연골세포적형태학변화.결과 술후3개월,C조T6～10、T10～14추체적평균고도분별위(26.81±1.70) mm、(27.43±2.92) mm,T6～10추간극적평균고도위(2.13±0.17)mm,여A조적(27.13 ±3.31)mm、(27.91±3.03) mm、(2.20±0.14)mm비교,차이균무통계학의의(P치균＞0.05),이여B조적(22.30±2.52)mm、(22.62±2.11)mm、(0.82±0.41)mm비교증가명현,차이균유통계학의의(P치균＜0.05),C조태봉상하량단활동평균거리42.7 mm.C조생장판연골세포층고도(165.6±1.7) μm여A조(167.2±6.8) μm비교차이무통계학의의(P＞0.05);이여B조(140.4±7.2) μm비교증가명현,차이유통계학의의(P＜0.05).결론 활조정생장봉내고정계통단변고정대유저척주생장발육무명현영향.
Objective To investigate the influence of the instrumentation growing rods of sliding pedicle screw system unilateral insertion on the growth of the spine in an animal model.Methods A total of 15 pigs (about 3-month age)were randomly assigned into 3 groups:group A,blank control group only exposing unilateral posterior lamellar; group B,unilateral inserting the traditional pedicle screw system; group C,unilateral inserting the instrumentation growing rods of sliding pedicle screw system.The average heights of T6 ～ 10,T10～14 and T6 ～ 10 dises,and the distance of both up-and down-ends of titanium rod sliding in group C were measured.X ray was used to examined the morphology of the spine.After 3-month observation,the animal samples are collected.selected segments of the fixed disc morphology was observed growth plate chondrocytes.Results Three months after operation,the average heights of T6～10 [(26.81 ± 1.70) mm],T1o～ 14 [(27.43 ± 2.92) mm],T6 ～ 10 [(2.13 ± 0.17)mm] discs and growth plate chondrocytes in group C had no remarkble difference from those in group A [(27.13 ± 3.31) mm,(27.91 ± 3.03) mm,(2.20 ± 0.14) mm,all P values ＞ 0.05],but significantly larger than in group B [(22.30 ± 2.52) mm,(22.62 ± 2.11) mm,(0.82 ± 0.41) mm,all P values ＜ 0.05].Growth occurred in both up-and down-ends of the titanium rods for a total average of 42.7 mm.The average height of growth plate chondrocytes in group C [(165.6 ± 1.7) μm] had no remarkble difference in group A [(167.2 ± 6.8) μm,P ＞ 0.05],but distinctly increased than that in group B [(140.4 ± 7.2) μm,P ＜ 0.05].Conclusions The unilateral instrumentation growing rods of sliding pedicle screw system placement has no evident influence on the progression of the immature porcine spine.