CAJ | 학술논문

目的观察脑电双频指数(BIS)监测值与重症监护室(ICU)中昏迷患者预后的相关性,探讨通过BIS值评估ICU昏迷患者的预后的可行性.方法回顾性将纳入的208例昏迷危重病患者根据所监测的BIS监测值分为四组:Ⅰ组,0～20;Ⅱ组,21 ～40;Ⅲ组,41～60;Ⅳ组,＞60.分别用BIS值和神志预后(神志清楚-昏迷、植物状态、脑死亡状态)为目标,比较组间差异,计算各组BIS值与昏迷患者预后的相关性,寻找较准确评估昏迷患者预后的BIS临界值.结果四组患者的年龄、APACHEⅡ评分采用单因素方差分析,差异无统计学意义(P＞0.05),对BIS值与昏迷预后状态采用Spearman’s等级相关进行相关分析,结果呈负相关(r=-0.749,P=O.00),根据ROC曲线,当BIS值＞42.5对神清-昏迷状态预后评估的敏感性及特异性较高.结论 BIS值与ICU昏迷患者的预后之间具有较好的相关性,BIS值可以对ICU昏迷患者的预后进行初步评估.
목적 관찰뇌전쌍빈지수(BIS)감측치여중증감호실(ICU)중혼미환자예후적상관성,탐토통과BIS치평고ICU혼미환자적예후적가행성.방법 회고성장납입적208례혼미위중병환자근거소감측적BIS감측치분위사조:Ⅰ조,0～20;Ⅱ조,21 ～40;Ⅲ조,41～60;Ⅳ조,＞60.분별용BIS치화신지예후(신지청초-혼미、식물상태、뇌사망상태)위목표,비교조간차이,계산각조BIS치여혼미환자예후적상관성,심조교준학평고혼미환자예후적BIS림계치.결과 사조환자적년령、APACHEⅡ평분채용단인소방차분석,차이무통계학의의(P＞0.05),대BIS치여혼미예후상태채용Spearman’s등급상관진행상관분석,결과정부상관(r=-0.749,P=O.00),근거ROC곡선,당BIS치＞42.5대신청-혼미상태예후평고적민감성급특이성교고.결론 BIS치여ICU혼미환자적예후지간구유교호적상관성,BIS치가이대ICU혼미환자적예후진행초보평고.
Objective To investigate the correlation between Bispectral index (BIS) value and the prognosis of patients with coma in ICU.Methods A total of 208 patients with coma in ICU were divided into 4 groups according to the BIS value.In group I,BIS value was 0 to 20; groupⅡ,BIS value 21 to 40; group Ⅲ,BIS value 41 to 60; and group Ⅳ,BIS value greater than 60.Comparison of the difference in BIS value with the differences in prognosis of patients with coma was carried out between four groups,and the prognosis of patients with coma was stratified into consciousness,coma,vegetative state,and brain death.Subsequently,the best cutoff score of BIS value calculated for determining the correlation between BIS and mental state was proposed.Results There are no significant differences in the age and APACHE Ⅱ scores between four groups (P ＞ 0.05).It was inverse correlation between BIS value and mental state (r =-0.749,P =0.00).According to the ROC curve,as BIS value was greater than 42.5,there were higher sensitivity and specificity in Conscious-Coma patients.Conclusions BIS value is correlated with the prognosis of patients with coma in ICU,and BIS value can be a useful marker for estimating the prognosis of comatose patients.