中华内分泌外科杂志
中華內分泌外科雜誌
중화내분비외과잡지
CHINESE JOURNAL OF ENDOCRINE SURGERY
2013年
5期
376-378
,共3页
乳腺导管原位癌%保乳治疗%乳房全切%局部复发%转移
乳腺導管原位癌%保乳治療%乳房全切%跼部複髮%轉移
유선도관원위암%보유치료%유방전절%국부복발%전이
Ductal carcinoma in situ%Breast-conserving therapy%Mastectomy%Local recurrence%Distant metastasis
目的 探讨乳腺导管原位癌(ductal carcinoma in situ,DCIS)保乳治疗的临床效果并对其安全性进行评价.方法 回顾温州医学院附属第一医院2010年3月至2013年3月进行保乳治疗的DCIS54例(实验组)及同期行乳房全切治疗的DCIS 49例(对照组),分析比较2组的局部复发(local recur-rence,LR)和远处转移情况及3年无病生存率(disease-free survival,DFS),评价保乳治疗的疗效和安全性.结果 所有患者均获随访,平均(22.3 ±8.5)(5～39)个月,实验组未出现LR,对照组胸壁复发1例,实验组1例出现远处转移,对照组出现2例远处转移；2组DFS分别为100％和95.9％,差异均无统计学意义(P＞0.05).结论 对DCIS采取保乳治疗和乳房全切治疗,术后LR和远处转移现象无明显差异,对DCIS行保乳治疗是安全的,可进一步推广.
目的 探討乳腺導管原位癌(ductal carcinoma in situ,DCIS)保乳治療的臨床效果併對其安全性進行評價.方法 迴顧溫州醫學院附屬第一醫院2010年3月至2013年3月進行保乳治療的DCIS54例(實驗組)及同期行乳房全切治療的DCIS 49例(對照組),分析比較2組的跼部複髮(local recur-rence,LR)和遠處轉移情況及3年無病生存率(disease-free survival,DFS),評價保乳治療的療效和安全性.結果 所有患者均穫隨訪,平均(22.3 ±8.5)(5～39)箇月,實驗組未齣現LR,對照組胸壁複髮1例,實驗組1例齣現遠處轉移,對照組齣現2例遠處轉移；2組DFS分彆為100％和95.9％,差異均無統計學意義(P＞0.05).結論 對DCIS採取保乳治療和乳房全切治療,術後LR和遠處轉移現象無明顯差異,對DCIS行保乳治療是安全的,可進一步推廣.
목적 탐토유선도관원위암(ductal carcinoma in situ,DCIS)보유치료적림상효과병대기안전성진행평개.방법 회고온주의학원부속제일의원2010년3월지2013년3월진행보유치료적DCIS54례(실험조)급동기행유방전절치료적DCIS 49례(대조조),분석비교2조적국부복발(local recur-rence,LR)화원처전이정황급3년무병생존솔(disease-free survival,DFS),평개보유치료적료효화안전성.결과 소유환자균획수방,평균(22.3 ±8.5)(5～39)개월,실험조미출현LR,대조조흉벽복발1례,실험조1례출현원처전이,대조조출현2례원처전이；2조DFS분별위100％화95.9％,차이균무통계학의의(P＞0.05).결론 대DCIS채취보유치료화유방전절치료,술후LR화원처전이현상무명현차이,대DCIS행보유치료시안전적,가진일보추엄.
Objective To explore the efficacy of breast-conserving therapy of ductal carcinoma in situ (DCIS),and to evaluate its safety.Methods 54 patients with DCIS receiving breast-conserving therapy(the experimental group) and 49 patients with DCIS treated with mastectomy(the control group) in the First Affiliated Hospital of Wenzhou Medical College from Mar.2010 to Mar.2013 were retrospectively analyzed.The follow-up results of the 2 groups were analyzed in terms of the local recurrence,distant metastasis and the 3-year diseasefree survival(DFS).The efficacy and safety of breast-conserving treatment were evaluated.Results All patients were followed up for 5 months to 39 months,with the average of(22.3 ± 8.5) months.No local recurrence happened in the experimental group.There was 1 case of chest wall recurrence in the control group.One case in the experimental group and 2 cases in the control group had distant metastasis.DFS rate in the 2 groups was 100％ and 95.9％ relatively.No statistically significant difference was found between the 2 group in terms of the above items (P ＞ 0.05).Conclusion For DCIS patients,the difference between breast-conserving therapy and mastectomy surgery in the rate of local recurrence and distant metastasis was not significant.Breast-conserving therapy is safe for DCIS patients and should be further promoted.
