中华实用儿科临床杂志
中華實用兒科臨床雜誌
중화실용인과림상잡지
Journal of Applied Clinical Pediatrics
2014年
9期
672-674
,共3页
孙丽红%陈爱欢%秦旭%黄顺开%黄穗%湛洁谊%曾莉君%周方略%钟南山
孫麗紅%陳愛歡%秦旭%黃順開%黃穗%湛潔誼%曾莉君%週方略%鐘南山
손려홍%진애환%진욱%황순개%황수%담길의%증리군%주방략%종남산
支气管哮喘%变应性鼻炎%儿童
支氣管哮喘%變應性鼻炎%兒童
지기관효천%변응성비염%인동
Asthma%Allergic rhinitis%Child
目的 观察不同年龄段支气管哮喘(哮喘)患儿中共患变应性鼻炎(AR)的情况,探讨哮喘与AR严重度的相关性.方法 选择广州地区首次就诊或既往诊断末规范治疗的2～14岁哮喘患儿,完成哮喘和AR情况调查表,检测血清变应原特异性IgE抗体.参照指南,评价哮喘和AR的严重度并进行相关性分析.结果 414例哮喘忠儿中,218例(52.7％)诊断为AR,6～＜12岁和12 ～ 14岁哮喘患儿共患AR的比率分别为62.4％ (123/197例)和 67.2％ (41/61例),明显高丁2～＜6岁的34.6％ (54/156例)(x2=33.1,P＜0.01).哮喘与AR的严重度在2～＜6岁二者无相关性(r=0.242,P=0.078),而在6～＜12岁(r=0.401,P=0.000)和12 ～14岁(r=0.516,P=0.001)二者呈显著正相关.2～14岁哮喘合并AR患儿吸入变应原阳性率排在前4位的为屋尘螨65.6％(143/218例)、粉尘螨64.7％(141/218例)、热带螨19.7％ (43/218例)和德国小蠊14.7％ (32/218例).结论 6岁以下哮喘患儿共患AR的比例低丁6岁以上的哮喘患儿.6岁以上儿章哮喘与AR的严重度呈显著正相关.屋尘螨和粉尘螨是广州地区哮喘共患AR患儿的主要吸入变应原.
目的 觀察不同年齡段支氣管哮喘(哮喘)患兒中共患變應性鼻炎(AR)的情況,探討哮喘與AR嚴重度的相關性.方法 選擇廣州地區首次就診或既往診斷末規範治療的2～14歲哮喘患兒,完成哮喘和AR情況調查錶,檢測血清變應原特異性IgE抗體.參照指南,評價哮喘和AR的嚴重度併進行相關性分析.結果 414例哮喘忠兒中,218例(52.7％)診斷為AR,6～＜12歲和12 ～ 14歲哮喘患兒共患AR的比率分彆為62.4％ (123/197例)和 67.2％ (41/61例),明顯高丁2～＜6歲的34.6％ (54/156例)(x2=33.1,P＜0.01).哮喘與AR的嚴重度在2～＜6歲二者無相關性(r=0.242,P=0.078),而在6～＜12歲(r=0.401,P=0.000)和12 ～14歲(r=0.516,P=0.001)二者呈顯著正相關.2～14歲哮喘閤併AR患兒吸入變應原暘性率排在前4位的為屋塵螨65.6％(143/218例)、粉塵螨64.7％(141/218例)、熱帶螨19.7％ (43/218例)和德國小蠊14.7％ (32/218例).結論 6歲以下哮喘患兒共患AR的比例低丁6歲以上的哮喘患兒.6歲以上兒章哮喘與AR的嚴重度呈顯著正相關.屋塵螨和粉塵螨是廣州地區哮喘共患AR患兒的主要吸入變應原.
목적 관찰불동년령단지기관효천(효천)환인중공환변응성비염(AR)적정황,탐토효천여AR엄중도적상관성.방법 선택엄주지구수차취진혹기왕진단말규범치료적2～14세효천환인,완성효천화AR정황조사표,검측혈청변응원특이성IgE항체.삼조지남,평개효천화AR적엄중도병진행상관성분석.결과 414례효천충인중,218례(52.7％)진단위AR,6～＜12세화12 ～ 14세효천환인공환AR적비솔분별위62.4％ (123/197례)화 67.2％ (41/61례),명현고정2～＜6세적34.6％ (54/156례)(x2=33.1,P＜0.01).효천여AR적엄중도재2～＜6세이자무상관성(r=0.242,P=0.078),이재6～＜12세(r=0.401,P=0.000)화12 ～14세(r=0.516,P=0.001)이자정현저정상관.2～14세효천합병AR환인흡입변응원양성솔배재전4위적위옥진만65.6％(143/218례)、분진만64.7％(141/218례)、열대만19.7％ (43/218례)화덕국소렴14.7％ (32/218례).결론 6세이하효천환인공환AR적비례저정6세이상적효천환인.6세이상인장효천여AR적엄중도정현저정상관.옥진만화분진만시엄주지구효천공환AR환인적주요흡입변응원.
Objective To observe the coexistence of allergic rhinitis (AR) in asthmatic children at different ages and to explore the correlation between the severity of asthma and AR.Methods This study was carried in asthmatic children aged 2-14 years.The questionnaire for asthma and AR was completed.All of the children underwent specific IgE (sIgE) to test common inhalant allergens.The classification and severity of asthma and AR were evaluated according to guidelines,respectively.Results Of 414 asthmatic children,218 patients (52.7％) presented with AR.The proportion of asthmatic chilren with AR less than 6 years old (34.6％,54/156 cases) was significantly lower than those aged6-＜12 years (62.4％,123/197 cases) and 12-14 years (67.2％,41/61 cases) (x2 =33.1,P＜0.01).A positive correlation was found between the severity of asthma and AR in children aged 6-＜ 12 years old (r =0.401,P =0.000) and 12-14 years old (r =0.516,P =0.001).However,there was no correlation between the severity of asthma and AR in children less than 6 years old (r =0.242,P =0.078).In 218 asthmatic children with AR,the positive rate of Dermatophagoides pteronyssinus (Der.p) was the highest (65.6％,143/218 cases),followed by Dermatophagoides farinae (Der.f) (64.7％,141/218 cases),Blomia tropicalis (19.7％,43/218 cases) and Blattella Germanica (14.7％,32/218 cases).Conclusions The proportion of asthmatic children less than 6 years old suffering from AR is lower than the children more than 6 years old.There is a positive correlation between the severity of asthma and AR in children aged 6-14 years.Der.P and Der.f are the main inhalant allergens of asthmatic children with AR in Guangzhou area.
