CAJ | 학술논문

神经母细胞瘤(NB)是儿童和婴儿最常见的颅外实体肿瘤,早期可发生转移,恶性度极高,临床差异很大,由于NB的生物异质性使其治疗方案较为复杂,不同的个体尚无统一的治疗方案.目前认为综合治疗仍是NB的主要治疗方法,包括手术切除、化疗、放射治疗、造血干细胞移植、131I-间位碘代苄胍、免疫治疗及靶向治疗等.现介绍一些NB常用的治疗方法,希望对NB的临床诊治有所帮助.
신경모세포류(NB)시인동화영인최상견적로외실체종류,조기가발생전이,악성도겁고,림상차이흔대,유우NB적생물이질성사기치료방안교위복잡,불동적개체상무통일적치료방안.목전인위종합치료잉시NB적주요치료방법,포괄수술절제、화료、방사치료、조혈간세포이식、131I-간위전대변고、면역치료급파향치료등.현개소일사NB상용적치료방법,희망대NB적림상진치유소방조.
Neuroblastoma is the most common extra-cranial solid tumor in infants and children,which is very easy to metastasis and its malignant degree is very high.Because of its clinical differences,so far treatment of neuroblastoma is still difficult.Currently comprehensive therapies,including surgery,chemotherapy,radiation,stem cell transplantation,131 I-meta-iodobenzylguanidine therapy,biological therapy and immune therapy as well as target therapy dominant the treatment of this disease,and introduce the some of the treatment protocols for this disease.