CAJ | 학술논문

目的探讨鼻咽癌放疗后发生张口困难的危险因素和保护因素,为临床提供有效的防范依据.方法对2008年1月至2011年1月放疗受照剂量一致的156例患者进行跟踪调查,观察张口困难的发生率及程度,并对可能引起张口困难的相关因素进行多因素Logistic回归分析.结果发生张口困难67例占42.949％,其程度随着放疗后时间的延长有加重的趋势；多因素Logistic回归分析显示,放射性口腔炎及皮炎、文化程度是放疗后发生张口困难的危险因素,功能锻炼依从性好是张口困难的保护因素.结论鼻咽癌患者放疗后发生张口困难的概率较高,应针对相关危险因素进行有效的预防和治疗,加强健康教育指导,提高功能锻炼依从性,降低张口困难的发生.
목적 탐토비인암방료후발생장구곤난적위험인소화보호인소,위림상제공유효적방범의거.방법 대2008년1월지2011년1월방료수조제량일치적156례환자진행근종조사,관찰장구곤난적발생솔급정도,병대가능인기장구곤난적상관인소진행다인소Logistic회귀분석.결과 발생장구곤난67례점42.949％,기정도수착방료후시간적연장유가중적추세；다인소Logistic회귀분석현시,방사성구강염급피염、문화정도시방료후발생장구곤난적위험인소,공능단련의종성호시장구곤난적보호인소.결론 비인암환자방료후발생장구곤난적개솔교고,응침대상관위험인소진행유효적예방화치료,가강건강교육지도,제고공능단련의종성,강저장구곤난적발생.
Objective To analyze the risk factors and protective factors of nasopharyngeal carcinoma patients having difficulty in opening mouth after radiotherapy,provide effective preventive measures for clinic.Methods From January 2008 to January 2011,156 cases of patients with the same radiotherapy exposure doses received tracking survey,the incidence and level of difficulty in opening mouth were observed,then the relevant factors which might cause the difficulty in opening mouth underwent Logistic regression analysis.Results 67 cases (42.949％) of patients after radiotherapy had difficulty in opening mouth; its degree got worse as the radiotherapy went on.Logistic regression analysis showed that radioactive stomatitis,dermatitis,education degree were the risk factors of difficulty in opening mouth after radiotherapy,a good compliance with functional training were the protective factor of difficulty in opening mouth.Conclusions Patients with nasopharyngeal carcinoma after radiotherapy have high occurrence of difficulty in opening mouth,so we should take effective prevention and treatment method aiming at the relevant factors,enhance health guidance,and improve functional exercise compliance,then reduce the occurrence of difficulty in opening mouth.