CAJ | 학술논문

目的了解广州地区健康人群中的EB病毒感染情况.方法采用ELISA法检测2007年1月至2011年12月本院体检的217 935例健康人的EB-VCA-IgA抗体,统计对比男女阳性率、5年间阳性率及各年龄段(≤29岁、30 ～ 39岁、40 ～ 49岁和≥50岁5个组)阳性率的差异.结果 EB-VCA-IgA抗体阳性4667例,总阳性率2.14％.其中男性135 985例,阳性率1.87％(2547/135 985)；女性81 950例,阳性率2.59％(2120/81 950),男女阳性率差异有统计学意义(P=0.000).5年间各年阳性率差异有统计学意义(x2=576.054,P=0.000).EB-VCA-IgA抗体的阳性率随着年龄的增长而增高,各年龄段差异均有统计学意义(P=0.000).结论广州地区健康人群中有一定比例的EB病毒感染者,且40岁以上健康人群感染率相对较高.
목적 료해엄주지구건강인군중적EB병독감염정황.방법 채용ELISA법검측2007년1월지2011년12월본원체검적217 935례건강인적EB-VCA-IgA항체,통계대비남녀양성솔、5년간양성솔급각년령단(≤29세、30 ～ 39세、40 ～ 49세화≥50세5개조)양성솔적차이.결과 EB-VCA-IgA항체양성4667례,총양성솔2.14％.기중남성135 985례,양성솔1.87％(2547/135 985)；녀성81 950례,양성솔2.59％(2120/81 950),남녀양성솔차이유통계학의의(P=0.000).5년간각년양성솔차이유통계학의의(x2=576.054,P=0.000).EB-VCA-IgA항체적양성솔수착년령적증장이증고,각년령단차이균유통계학의의(P=0.000).결론 엄주지구건강인군중유일정비례적EB병독감염자,차40세이상건강인군감염솔상대교고.
Objective To determine the Epstein-Barr virus(EBV) infection in healthy population in Guangzhou.Methods A total of 217 935 healthy individuals who received health check-up in The General Hospital of Guangzhou Military Command between January 2007 and December 2011 underwent screening of EBVCA-IgA antibody via enzyme-linked immunosorbent assay.This was followed by comparison on positive rate of both sexes,within the 5 years and at various age groups(≤29 years,30-35 years,40-49 years and ≥50 years).Results Of 217 935 individuals assayed,4667(2.14％) were positive to EB-VCA-IgA antibody.The positive rate differed significantly(P=0.000) between males(1.87％,2547/135 985) and females (2120/81 950,2.59％)and varied within the 5 years (x2=576.054,P=0.000).The positive rate of EB-VCA-IgA antibody varied among different age groups(P=0.000),and increased with the age.Conclusions EB virus infection can be found in a subgroup of healthy population in Guangzhou.A higher incidence of EBV infection is mostly associated with healthy individuals aged ＞40 years.