中华生物医学工程杂志
中華生物醫學工程雜誌
중화생물의학공정잡지
CHINESE JOURNAL OF BIOMEDICAL ENGINEERING
2013年
3期
210-215
,共6页
孙媛媛%梁萍%董磊%张国明%程志刚%王洋%高永艳%邵秋杰
孫媛媛%樑萍%董磊%張國明%程誌剛%王洋%高永豔%邵鞦傑
손원원%량평%동뢰%장국명%정지강%왕양%고영염%소추걸
微波%导管消融术%肝肿瘤%温度曲线%消融区域
微波%導管消融術%肝腫瘤%溫度麯線%消融區域
미파%도관소융술%간종류%온도곡선%소융구역
Microwave%Catheter ablation%Liver neoplasms%Temperature curve%Ablation zone
目的 比较水冷915 MHz和2450 MHz微波在活体与离体猪肝实验中温度曲线和消融区的差异.方法 使用915和2450 MHz微波消融和热监测系统,共获得58个消融区和180个温度数据.输出设置为915 MHz 50 W,70 W和2450 MHz 50 W,70 W,并设置时间为600 s.每个温度点的温度曲线在天线旁开5、10、15 mm处,对消融区的宽径和长径进行测量.结果 在活体与离体实验中,除旁开5 mm,915 MHz水冷微波其余点的峰值温度[活体50 W 10 mm:(59±4.26)℃;70 W 10 mm:(67±9.01)℃]均高于2450 MHz微波[活体50 W 10 mm:(54±4.09)℃;70 W 10 mm:(57±6.13)℃](P<0.05).在相同条件下,离体肝脏的消融区宽径和长径[活体50W宽径:(3.13±0.76)cm;长径(4.95±0.87)cm]均显着大于2450 MHz微波[活体50 W宽径:(2.34±0.49)cm;长径(3.43±0.96)cm](P< 0.05).结论 在离体和活体的肝脏实验中,915 MHz水冷微波比2450 MHz可以形成更大的消融区和达到更高的温度.
目的 比較水冷915 MHz和2450 MHz微波在活體與離體豬肝實驗中溫度麯線和消融區的差異.方法 使用915和2450 MHz微波消融和熱鑑測繫統,共穫得58箇消融區和180箇溫度數據.輸齣設置為915 MHz 50 W,70 W和2450 MHz 50 W,70 W,併設置時間為600 s.每箇溫度點的溫度麯線在天線徬開5、10、15 mm處,對消融區的寬徑和長徑進行測量.結果 在活體與離體實驗中,除徬開5 mm,915 MHz水冷微波其餘點的峰值溫度[活體50 W 10 mm:(59±4.26)℃;70 W 10 mm:(67±9.01)℃]均高于2450 MHz微波[活體50 W 10 mm:(54±4.09)℃;70 W 10 mm:(57±6.13)℃](P<0.05).在相同條件下,離體肝髒的消融區寬徑和長徑[活體50W寬徑:(3.13±0.76)cm;長徑(4.95±0.87)cm]均顯著大于2450 MHz微波[活體50 W寬徑:(2.34±0.49)cm;長徑(3.43±0.96)cm](P< 0.05).結論 在離體和活體的肝髒實驗中,915 MHz水冷微波比2450 MHz可以形成更大的消融區和達到更高的溫度.
목적 비교수랭915 MHz화2450 MHz미파재활체여리체저간실험중온도곡선화소융구적차이.방법 사용915화2450 MHz미파소융화열감측계통,공획득58개소융구화180개온도수거.수출설치위915 MHz 50 W,70 W화2450 MHz 50 W,70 W,병설치시간위600 s.매개온도점적온도곡선재천선방개5、10、15 mm처,대소융구적관경화장경진행측량.결과 재활체여리체실험중,제방개5 mm,915 MHz수랭미파기여점적봉치온도[활체50 W 10 mm:(59±4.26)℃;70 W 10 mm:(67±9.01)℃]균고우2450 MHz미파[활체50 W 10 mm:(54±4.09)℃;70 W 10 mm:(57±6.13)℃](P<0.05).재상동조건하,리체간장적소융구관경화장경[활체50W관경:(3.13±0.76)cm;장경(4.95±0.87)cm]균현착대우2450 MHz미파[활체50 W관경:(2.34±0.49)cm;장경(3.43±0.96)cm](P< 0.05).결론 재리체화활체적간장실험중,915 MHz수랭미파비2450 MHz가이형성경대적소융구화체도경고적온도.
Objective To compare temperature curve and ablation zone between 915 and 2450 MHz cooled-shaft microwave antenna for porcine livers in vivo and in vitro.Methods The 915 and 2450 MHz microwave ablation and thermal monitor system were used in this study.A total of 58 ablation zones and 180 temperature data were obtained from porcine livers in vivo and in vitro.The output settings were 915 MHz 50 W,70 W and 2450 MHz 50 W,70 W,and the setting time was 600 s.The temperature curve of every temperature spot was at 5,10,15 mm away from the antenna,and the short-and long-axis diameters of the coagulation zones were measured.Results The peak temperatures for the 915 MHz cooled-shaft antenna[in vivo 50 W 10 mm:(59±4.26)℃ ; 70 W 10 mm:(67±9.01)℃] were significantly higher than those for the 2450 MHz cooled-shaft antenna [in vivo 50 W 10 mm:(54±4.09)℃ ; 70 W 10 mm:(57±6.13)℃] in both in vitro and in vivo livers except for 5 mm away from the antenna in vitro liver(P<0.05).Meanwhile,the shortand long-axis diameters for the 915 MHz cooled-shaft antenna[in vivo 50 W short-axis:(3.13±0.76)cm; long-axis (4.95±0.87)cm] were significantly larger than those for the 2450 MHz cooled-shaft antenna[in vivo 50 W short-axis:(2.34±0.49) cm;long-axis (3.43±0.96) cm] in both in vitro and in vivo porcine livers (P<0.05).At the same setting,the short-and long-axis diameters in the in vitro liver increased compared to those in vivo liver,and in 70 W power setting,the peak temperature of every surveying spot in the in vitro liver was significantly higher than that in the in vivo liver (P<0.05).Conclusion The 915 MHz cooled-shaft antenna can yield a significantly larger ablation zone and achieve higher temperature in ablation zone than a 2450 MHz cooled-shaft antenna in both in vitro and in vivo livers.