CAJ | 학술논문

目的探究超高龄(≥80岁)原发性脑出血患者的临床特点和预后情况.方法回顾性分析本院2011年1月至2013年1月期间收治170例原发性脑出血患者临床资料(超高龄者45例,对照组125例).对比超高龄患者(≥80岁)和对照组(＜80岁)在临床症状、体征、影像学表现、疾病治疗等的差异,比较分析两组患者的生存情况.结果超高龄组中,女性所占的比例高于对照组,既往有高血压病史者、起病时有明确诱因或处于活动状态、入院时收缩压、舒张压低于对照组(P＜0.05).超高龄组脑叶出血的情况多于对照组(31.1％比12.0％,P＜0.05),基底节出血的情况则少于对照组(37.8％比62.4％,P＜0.05);超高龄组采用手术治疗低于对照组,在住院时间上长于对照组,中位累积生存时间低于对照组(P＜0.05).结论超高龄原发性脑出血可能是一种特殊类别的脑出血,脑血管淀粉样变性极有可能是其发病的重要病因.
목적 탐구초고령(≥80세)원발성뇌출혈환자적림상특점화예후정황.방법 회고성분석본원2011년1월지2013년1월기간수치170례원발성뇌출혈환자림상자료(초고령자45례,대조조125례).대비초고령환자(≥80세)화대조조(＜80세)재림상증상、체정、영상학표현、질병치료등적차이,비교분석량조환자적생존정황.결과 초고령조중,녀성소점적비례고우대조조,기왕유고혈압병사자、기병시유명학유인혹처우활동상태、입원시수축압、서장압저우대조조(P＜0.05).초고령조뇌협출혈적정황다우대조조(31.1％비12.0％,P＜0.05),기저절출혈적정황칙소우대조조(37.8％비62.4％,P＜0.05);초고령조채용수술치료저우대조조,재주원시간상장우대조조,중위루적생존시간저우대조조(P＜0.05).결론 초고령원발성뇌출혈가능시일충특수유별적뇌출혈,뇌혈관정분양변성겁유가능시기발병적중요병인.
Objective To investigate the clinical characteristics and outcomes of primary intracerebral hemorrhage (PICH) in very elderly patients aged over 80 years.Methods The clininl data of 170 patients who were diagnosed with PICH in our hospital between January 2011 and January 2013 were retrospectively analyzed.These patients comprised 45 very elderly subjects (≥80 years old) and 125 controls aged below 80.The differences in the clinical symptoms,signs,radiographic manifestations and treatments between the very elderly patients and the controls were compared.The survival in the both groups was also analyzed.Results Compared with controls,the very elderly group showed a higher proportion of female gender,and were less likely to have a past history of hypertension,obvious predisposing factors or activities prior to onset,and had lower systolic and diastolic blood pressures at admission.Cerebellar hemorrhage was more common (31.1％ vs 12.0％,P＜0.05),while the basal ganglia hemorrhage was less frequent (37.8％vs 62.4％,P＜0.05),in the very elderly group than in the control group.Compared with the controls,lower rate of surgery treatment,longer hospital stay and shorter median survival time were found for the very elderly group (P＜0.05).Conclusion PICH in the very elderly patients appears to be a unique category of cerebral hemorrhage,which may be significantly associated with cerebrovascular amyloidosis.