中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
CHINESE PEDIATRIC EMERGENCY MEDICINE
2014年
5期
268-270
,共3页
曹亚芹%于鑫光%董玉斌%卢秀丽%李雪莲
曹亞芹%于鑫光%董玉斌%盧秀麗%李雪蓮
조아근%우흠광%동옥빈%로수려%리설련
振幅整合脑电图%新生儿窒息%新生儿%预后
振幅整閤腦電圖%新生兒窒息%新生兒%預後
진폭정합뇌전도%신생인질식%신생인%예후
Amplitude integrated electroencephalography%Neonatal asphyxia%Neonate%Prognosis
目的 探讨振幅整合脑电图(amplitude integrated electroencephalographic,aEEG)在窒息新生儿早期脑损伤及预后预测中的应用价值.方法 将72例窒息患儿分为轻度窒息组和重度窒息组,选择同期我院产科出生的健康足月儿45例为健康对照组.在生后6h内对所有观察对象进行aEEG监测,按aEEG结果把全部患儿分为正常aEEG组、轻度异常aEEG组、重度异常aEEG组,于1岁时,对研究对象与对照组同时进行生长发育及神经心理发育情况随访.结果 轻度窒息组、重度窒息组aEEG异常发生率明显高于正常对照组(x2=26.996、47.07,P均＜0.01),重度窒息组aEEG异常发生率明显高于轻度窒息组(x2 =7.76,P ＜0.05);全部患儿体格发育(身长和体重)比较差异无统计学意义(P＞0.05);重度异常aEEG组患儿的头围偏小(x2=8.734,P＜0.01;Spearman等级相关系数为0.62,P＜0.05)及智力指数、发育商偏低(x2=13.450、15.285,P均＜0.01;Spearman等级相关系数为0.73、0.75,P均＜0.05).结论 aEEG可用于窒息新生儿早期脑损伤的脑功能评价,通过aEEG异常程度可预测窒息新生儿预后.
目的 探討振幅整閤腦電圖(amplitude integrated electroencephalographic,aEEG)在窒息新生兒早期腦損傷及預後預測中的應用價值.方法 將72例窒息患兒分為輕度窒息組和重度窒息組,選擇同期我院產科齣生的健康足月兒45例為健康對照組.在生後6h內對所有觀察對象進行aEEG鑑測,按aEEG結果把全部患兒分為正常aEEG組、輕度異常aEEG組、重度異常aEEG組,于1歲時,對研究對象與對照組同時進行生長髮育及神經心理髮育情況隨訪.結果 輕度窒息組、重度窒息組aEEG異常髮生率明顯高于正常對照組(x2=26.996、47.07,P均＜0.01),重度窒息組aEEG異常髮生率明顯高于輕度窒息組(x2 =7.76,P ＜0.05);全部患兒體格髮育(身長和體重)比較差異無統計學意義(P＞0.05);重度異常aEEG組患兒的頭圍偏小(x2=8.734,P＜0.01;Spearman等級相關繫數為0.62,P＜0.05)及智力指數、髮育商偏低(x2=13.450、15.285,P均＜0.01;Spearman等級相關繫數為0.73、0.75,P均＜0.05).結論 aEEG可用于窒息新生兒早期腦損傷的腦功能評價,通過aEEG異常程度可預測窒息新生兒預後.
목적 탐토진폭정합뇌전도(amplitude integrated electroencephalographic,aEEG)재질식신생인조기뇌손상급예후예측중적응용개치.방법 장72례질식환인분위경도질식조화중도질식조,선택동기아원산과출생적건강족월인45례위건강대조조.재생후6h내대소유관찰대상진행aEEG감측,안aEEG결과파전부환인분위정상aEEG조、경도이상aEEG조、중도이상aEEG조,우1세시,대연구대상여대조조동시진행생장발육급신경심리발육정황수방.결과 경도질식조、중도질식조aEEG이상발생솔명현고우정상대조조(x2=26.996、47.07,P균＜0.01),중도질식조aEEG이상발생솔명현고우경도질식조(x2 =7.76,P ＜0.05);전부환인체격발육(신장화체중)비교차이무통계학의의(P＞0.05);중도이상aEEG조환인적두위편소(x2=8.734,P＜0.01;Spearman등급상관계수위0.62,P＜0.05)급지력지수、발육상편저(x2=13.450、15.285,P균＜0.01;Spearman등급상관계수위0.73、0.75,P균＜0.05).결론 aEEG가용우질식신생인조기뇌손상적뇌공능평개,통과aEEG이상정도가예측질식신생인예후.
Objective To discuss the value of amplitude integrated electroencephalographic(aEEG) monitoring in early neonatal brain injury and prognosis of asphyxia neonatal.Methods Seventy-two subjects of asphyxia children were divided into mild asphyxia group and severe asphyxia group.We selected 45 cases of full-term healthy children born in our hospital as control group in the same term.All the objects were observed by aEEG monitoring within 6 hours.According to the aEEG results,all the samples were redivided into normal aEEG group,mildly abnormal aEEG group and severely abnormal aEEG group.All subjects were followed-up to observe their physical growth and the nervous system development at one-year-old.Results Incidence of abnormal aEEG in mild asphyxia group and severe asphyxia group was significantly higher than that of control group(x2 =26.996,47.07,P ＜ 0.01,respectively),and incidence of abnormal aEEG in severe asphyxia group was significantly higher than that of mild asphyxia group (x2 =7.76,P ＜ 0.05).There was no significant difference in all subjects about physical development (height and weight) (P ＞ 0.05),all of their mental index and developmental quotient were lower in severely abnormal aEEG group (x2 =13.450,15.285,P ＜ 0.01,respectively).Conclusion aEEG can be used to assess the early neonatal brain injury of asphyxia neonatal,and it can be used to predict the prognosis of neonatal asphyxia based on the abnormal degree of aEEG.
