CAJ | 학술논문

目的探讨小儿神经节细胞瘤的诊断及治疗.方法结合相关文献对我科18例小儿神经节细胞瘤患儿的临床资料进行回顾性分析.男7例,女11例,年龄2～9岁,平均4岁.腹膜后8例,后纵膈6例,肾上腺4例.结合患儿临床表现及彩超、CT等影像学检查,14例术前考虑为神经节细胞瘤,2例误诊为神经母细胞瘤,1例误诊为嗜铬细胞瘤,1例误诊为肾母细胞瘤.结果 18例患儿均行手术治疗,14例完整切除瘤体,2例椎管内残存有瘤体组织,2例仅行活检.随访17例,随访时间7 d～7年,15例存活,2例死亡,2例复发.结论小儿神经节细胞瘤为起源于交感神经节的良性肿瘤,较为少见,发病年龄较大,瘤体生长缓慢,全身症状较轻,实验检查常无异常,完整切除后很少复发,术中应避免损伤腔静脉、腹主动脉,不可盲目处理伸向瘤体内部血管,如瘤体延伸至椎间孔内,为避免损伤神经根、脊髓,术后常有部分残余.
목적 탐토소인신경절세포류적진단급치료.방법 결합상관문헌대아과18례소인신경절세포류환인적림상자료진행회고성분석.남7례,녀11례,년령2～9세,평균4세.복막후8례,후종격6례,신상선4례.결합환인림상표현급채초、CT등영상학검사,14례술전고필위신경절세포류,2례오진위신경모세포류,1례오진위기락세포류,1례오진위신모세포류.결과 18례환인균행수술치료,14례완정절제류체,2례추관내잔존유류체조직,2례부행활검.수방17례,수방시간7 d～7년,15례존활,2례사망,2례복발.결론 소인신경절세포류위기원우교감신경절적량성종류,교위소견,발병년령교대,류체생장완만,전신증상교경,실험검사상무이상,완정절제후흔소복발,술중응피면손상강정맥、복주동맥,불가맹목처리신향류체내부혈관,여류체연신지추간공내,위피면손상신경근、척수,술후상유부분잔여.
Objective To study the clinical characteristics of gangliocytoma in children.Methods In this study,the clinical data of 18 children with gangliocytoma were analyzed.The relevant literatures were reviewed.Among these patients,8 cases were diagnosed with retroperitoneal gangliocytoma,6 were posterior mediastinal gangliocytoma,and the other 4 were adrenal gangliocytoma.Based on the preoperative ultrasonography and CT scanning,14 cases were diagnosed as gangliocytoma,2 were misdiagnosed as neuroblastoma,1 was misdiagnosed as pheochromocytoma,and 1 was misdiagnosed as nephroblastoma.Results All patients underwent surgery.Among them,gangliocytoma was completely removed on 14 patients,and partly removed on 2.Two patients' tumors were failed to remove and biopsy was performed to confirm the diagnosis.The patients were followed up for 7 day to 7 years.Fifteen patients survived,and 2 died.Gangliocytoma reoccurred on 2 patients.Conclusions Preoperative diagnosis of ganglioeytoma relies on radiological study.Complete resection is the primary goal of surgery.