CAJ | 학술논문

目的分析微创颅骨钻孔引流术治疗化脓性脑膜炎合并硬膜下积液术后硬膜下积液中蛋白含量、白细胞数及颅内压变化情况.方法回顾性分析2008年8月至2011年8月我科收治的60例因化脓性脑膜炎并发硬膜下积液行微创颅骨钻孔引流术患儿的临床资料.分析术中、术后1、3、7、10d及2周时硬膜下积液标本中白细胞数量、蛋白含量及颅内压力变化情况.结果 60例患儿术后硬膜下积液中蛋白含量、白细胞数量及颅内压力随时间逐渐下降,术后7～10d时逐渐降至一个平台期,此后逐渐稳定.白细胞数与蛋白含量相关系数为0.6,蛋白含量与颅内压力相关系数为0.3,白细胞数与颅内压力相关系数为0.6(P均＜0.01).结论术后白细胞数、蛋白含量及颅内压三者成正相关,术后2周左右三者指标趋于稳定为拔管最佳时机,术后积极应用抗生素冲洗能有效地缩短病程.
목적 분석미창로골찬공인류술치료화농성뇌막염합병경막하적액술후경막하적액중단백함량、백세포수급로내압변화정황.방법 회고성분석2008년8월지2011년8월아과수치적60례인화농성뇌막염병발경막하적액행미창로골찬공인류술환인적림상자료.분석술중、술후1、3、7、10d급2주시경막하적액표본중백세포수량、단백함량급로내압력변화정황.결과 60례환인술후경막하적액중단백함량、백세포수량급로내압력수시간축점하강,술후7～10d시축점강지일개평태기,차후축점은정.백세포수여단백함량상관계수위0.6,단백함량여로내압력상관계수위0.3,백세포수여로내압력상관계수위0.6(P균＜0.01).결론 술후백세포수、단백함량급로내압삼자성정상관,술후2주좌우삼자지표추우은정위발관최가시궤,술후적겁응용항생소충세능유효지축단병정.
Objective To study the changes of protein content,leukocytes number in subdural effusion and intracranial pressure in children after the minimally invasive treatment for subdural effusion complicating purulent meningitis.Methods Sixty cases who were performed with minimally invasive cranial drilling drainage between August 2008 and August 2011 were retrospectively analyzed.Leukocytes number and protein content in subdural effusion and intracranial pressure were detected during operation and 1,3,7,10 days and 2 weeks postoperatively,respectively.Results Protein content and leukocytes number in subdural effusion and intracranial pressure declined postoperatively with time gradually to a platform after 7 to 10 days,and then kept stable.Correlation coefficient for leukocytes number and protein content was 0.6 (P＜0.01),correlation coefficient for protein content and intracranial pressure was 0.3 (P＜0.01),correlation coefficient for leukocytes number and intracranial pressure was 0.6 (P＜0.01).Conclusions Leukocyte count,protein content and the intracranial pressure are linearly correlated.The three parameters tend to be more stable after 2 weeks,so 2 weeks after operation is an optimal timing for extubation.Antibiotics rinse can effectively shorten the duration of symptoms.