中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2012年
12期
1114-1117
,共4页
沈政伟%尹禾%薛林平%姜黎%刘洪%李丽%吴金桃
瀋政偉%尹禾%薛林平%薑黎%劉洪%李麗%吳金桃
침정위%윤화%설림평%강려%류홍%리려%오금도
生物测量/Lenstar生物测量仪,A型超声,角膜曲率计%眼轴长度%角膜曲率%人工晶状体%白内障
生物測量/Lenstar生物測量儀,A型超聲,角膜麯率計%眼軸長度%角膜麯率%人工晶狀體%白內障
생물측량/Lenstar생물측량의,A형초성,각막곡솔계%안축장도%각막곡솔%인공정상체%백내장
Bio-measurement/Lenstar,A-scan ultrasound biometry,keratometer%Ocular axial length%Corneal curvature%Intraocular lens%Cataract
背景 精确的眼部生物学参数对眼科疾病的诊断、治疗及预后有着重要的意义,筛选简便、准确测量眼部生物学参数的方法至关重要. 目的 比较Lenstar LS900型光学生物测量仪与A型超声或角膜曲率计在测量眼轴长度、角膜曲率(K1、K2、Km)以及预测人工晶状体(IOL)度数方面的差异,为Lenstar光学生物测量仪的临床应用提供依据.方法 共纳入年龄相关性白内障患者40例43眼,分别应用Lenstar、A型超声法或角膜曲率计测量受检眼眼轴长度及K1、K2、Km值,计算IOL度数.采用配对t检验对两种测量结果的差异进行比较,两种方法测量结果的一致性评价采用Bland-Altamn分析. 结果 共有35眼完成测量.Lenstar与A型超声测量的眼轴长度分别为(23.341±1.208) mm和(23.268±1.157) mm,二者比较差异无统计学意义(t=0.260,P=0.796).Lenstar与角膜曲率计测量K1、K2、Km值的差异均无统计学意义(t=0.526,P=0.601;t=0.927,P=0.357;t=0.213,P=0.832).两种方法预测的IOL度数分别为(20.371±2.827)D和(20.729±2.672)D,二者比较差异无统计学意义(t=0.543,P=0.589).Bland-Altamn一致性检验表明,Lenstar与A型超声或角膜曲率计测量的眼轴长度,K1、K2、Km值以及IOL度数分别有11% (4/35)、0%(0/100)、9%(3/35)、9%(3/35)、6%(2/35)的点位于95%的一致性界限以外,在一致性界限内最大差值的绝对值为0.39 mm和1.31、1.30、0.77、1.00 D.结论 Lenstar能够检测多种测量指标,测量过程具有非侵入性、方便快捷、用时较短等优点,但本研究的结果认为Lenstar与A型超声或角膜曲率计的方法一致性不好,二者是否可以互相替代还需要进一步的大样本临床研究证实.
揹景 精確的眼部生物學參數對眼科疾病的診斷、治療及預後有著重要的意義,篩選簡便、準確測量眼部生物學參數的方法至關重要. 目的 比較Lenstar LS900型光學生物測量儀與A型超聲或角膜麯率計在測量眼軸長度、角膜麯率(K1、K2、Km)以及預測人工晶狀體(IOL)度數方麵的差異,為Lenstar光學生物測量儀的臨床應用提供依據.方法 共納入年齡相關性白內障患者40例43眼,分彆應用Lenstar、A型超聲法或角膜麯率計測量受檢眼眼軸長度及K1、K2、Km值,計算IOL度數.採用配對t檢驗對兩種測量結果的差異進行比較,兩種方法測量結果的一緻性評價採用Bland-Altamn分析. 結果 共有35眼完成測量.Lenstar與A型超聲測量的眼軸長度分彆為(23.341±1.208) mm和(23.268±1.157) mm,二者比較差異無統計學意義(t=0.260,P=0.796).Lenstar與角膜麯率計測量K1、K2、Km值的差異均無統計學意義(t=0.526,P=0.601;t=0.927,P=0.357;t=0.213,P=0.832).兩種方法預測的IOL度數分彆為(20.371±2.827)D和(20.729±2.672)D,二者比較差異無統計學意義(t=0.543,P=0.589).Bland-Altamn一緻性檢驗錶明,Lenstar與A型超聲或角膜麯率計測量的眼軸長度,K1、K2、Km值以及IOL度數分彆有11% (4/35)、0%(0/100)、9%(3/35)、9%(3/35)、6%(2/35)的點位于95%的一緻性界限以外,在一緻性界限內最大差值的絕對值為0.39 mm和1.31、1.30、0.77、1.00 D.結論 Lenstar能夠檢測多種測量指標,測量過程具有非侵入性、方便快捷、用時較短等優點,但本研究的結果認為Lenstar與A型超聲或角膜麯率計的方法一緻性不好,二者是否可以互相替代還需要進一步的大樣本臨床研究證實.
배경 정학적안부생물학삼수대안과질병적진단、치료급예후유착중요적의의,사선간편、준학측량안부생물학삼수적방법지관중요. 목적 비교Lenstar LS900형광학생물측량의여A형초성혹각막곡솔계재측량안축장도、각막곡솔(K1、K2、Km)이급예측인공정상체(IOL)도수방면적차이,위Lenstar광학생물측량의적림상응용제공의거.방법 공납입년령상관성백내장환자40례43안,분별응용Lenstar、A형초성법혹각막곡솔계측량수검안안축장도급K1、K2、Km치,계산IOL도수.채용배대t검험대량충측량결과적차이진행비교,량충방법측량결과적일치성평개채용Bland-Altamn분석. 결과 공유35안완성측량.Lenstar여A형초성측량적안축장도분별위(23.341±1.208) mm화(23.268±1.157) mm,이자비교차이무통계학의의(t=0.260,P=0.796).Lenstar여각막곡솔계측량K1、K2、Km치적차이균무통계학의의(t=0.526,P=0.601;t=0.927,P=0.357;t=0.213,P=0.832).량충방법예측적IOL도수분별위(20.371±2.827)D화(20.729±2.672)D,이자비교차이무통계학의의(t=0.543,P=0.589).Bland-Altamn일치성검험표명,Lenstar여A형초성혹각막곡솔계측량적안축장도,K1、K2、Km치이급IOL도수분별유11% (4/35)、0%(0/100)、9%(3/35)、9%(3/35)、6%(2/35)적점위우95%적일치성계한이외,재일치성계한내최대차치적절대치위0.39 mm화1.31、1.30、0.77、1.00 D.결론 Lenstar능구검측다충측량지표,측량과정구유비침입성、방편쾌첩、용시교단등우점,단본연구적결과인위Lenstar여A형초성혹각막곡솔계적방법일치성불호,이자시부가이호상체대환수요진일보적대양본림상연구증실.
Background The accuracy of biometric measurement is critical for precise diagnoses and prognosis evaluation of ocular diseases.Objective The present study was to evaluate the differences of Lenstar with A-scan ultrasound biometry or keratometer in ocular bio-measurement.Methods Written informed consent was obtained from each subject before examination.Total 43 eyes of 40 age-related cataract patients were enrolled in this study.Axial length,corneal curvature (K1,K2,Km) and intraocular lens (IOL) power were measured with Lenstar,A-scan ultrasound biometry and keratometer,separately.The differences of measuring outcomes were compared between these two methods according to a paired samples t test,and the agreement analysis of measuring outcomes between Lenstar and A-scan ultrasound biometry or keratometer was performed by Blant-Altman plots.Results Thirty-five eyes finished the clinical bio-measurement.The axial length was (23.341 ± 1.208) mm and (23.268 ±1.157)mm based on Lenstar method and A-scan ultrasound biometry method,respectively,with a insignificant difference between them(t =0.260,P=0.796).No significant differences were found in the K1,K2 and Km values between Lenstar and keratometer methods (t =0.526,P =0.601 ; t =0.927,P =0.357 ; t =0.213,P =0.832).The IOL power was (20.371 ±2.827) D and (20.729 ± 2.672) D,respectively in Lenstar method and keratometer method,without statistically significant difference between them (t =0.543,P =0.589).Bland-Altamn agreement analysis showed that the dots of 11% (4/35),0% (0/100),9%(3/35),9% (3/35),6% (2/35) were out of 95% confidence limit,and the absolute values of maximal difference value between Lenstar and A-scan ultrasound biometry or keratometer methods was 0.39 mm,1.31 D,1.30 D,0.77 D and 1.00 D in ocular axial length,K1,K2 and Km values and IOL power,respectively.Conclusions As a new bio-measuring method,Lenstar can offer multiple biometric parameters by single procedure.However,an inconsistent measuring outcome is seen between Lenstar and Ascan ultrasound biometry or keratometer.So whether Lenstar can replace A-scan ultrasound biometry or keratometer still need further large simple clinical trail.