中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2012年
10期
604-608
,共5页
刘洋辰%王雁%左彤%耿维莉%金颖
劉洋辰%王雁%左彤%耿維莉%金穎
류양신%왕안%좌동%경유리%금영
近视%角膜厚度%屈光度%曲率
近視%角膜厚度%屈光度%麯率
근시%각막후도%굴광도%곡솔
Myopia%Corneal thickness%Diopter%Curvature
目的 探讨近视眼患者角膜不同区域厚度及其差异与屈光度、曲率之间的关系.方法 横断面研究.近视及近视散光患者264例(458眼),男122例,女142例.应用Pentacam眼前节测量分析系统对近视眼角膜厚度进行测量分析,选取角膜顶点、中央、最薄点；角膜厚度及角膜前表面切线曲率测量均取以角膜顶点为中心的2 mm、4 mm、6 mm、8 mm直径虚拟圆,以双眼颞侧水平设为0°,右眼顺时针、左眼逆时针递增记录可查位点的角膜厚度平均值及角膜切线曲率平均值.依据屈光状态不同分为低度近视组(屈光度≤-3.00 D)、中度近视组(-3.00 D＜屈光度≤-6.00 D)和高度近视组(-6.00 D ＜屈光度).多组间比较采用方差分析,左右眼比较应用独立样本t检验,不同位点角膜厚度相关性以及角膜厚度与其他因素相关性应用Pearson相关分析.结果 458眼角膜顶点、中央、最薄点厚度平均值分别为(529.58±22.38) μm、(529.75±22.51)μm、(527.78±22.71)μm.围绕角膜顶点的不同直径虚拟圆上角膜厚度最大平均值均位于90°位点,其平均值分别为(544.14±22.07) μm、(583.15±24.72) μm、(646.27±27.34) μm、(716.52±27.70)μm.围绕角膜顶点的2 mm、4 mm、6 mm、8 mm直径虚拟圆上角膜厚度最小平均值分别位于315°、315 °、337.5°、342°,其平均值分别为(532.48±23.51) μm、(549.24±26.97) μm、(590.02±27.06) μm、(657.37±32.03) μm.左右眼角膜中央、顶点和最薄点厚度呈正相关(r=0.768、0.548、0.671,P均＜0.05).低、中、高屈光度与角膜不同区域厚度的平均值均无相关性,低、中、高屈光度组角膜厚度与切线曲率均无相关性.结论 近视眼患者角膜不同直径虚拟圆范围内,上方角膜厚度最厚,颞侧及颞下方角膜厚度最薄.角膜厚度与屈光度和角膜前表面曲率均无相关性.
目的 探討近視眼患者角膜不同區域厚度及其差異與屈光度、麯率之間的關繫.方法 橫斷麵研究.近視及近視散光患者264例(458眼),男122例,女142例.應用Pentacam眼前節測量分析繫統對近視眼角膜厚度進行測量分析,選取角膜頂點、中央、最薄點；角膜厚度及角膜前錶麵切線麯率測量均取以角膜頂點為中心的2 mm、4 mm、6 mm、8 mm直徑虛擬圓,以雙眼顳側水平設為0°,右眼順時針、左眼逆時針遞增記錄可查位點的角膜厚度平均值及角膜切線麯率平均值.依據屈光狀態不同分為低度近視組(屈光度≤-3.00 D)、中度近視組(-3.00 D＜屈光度≤-6.00 D)和高度近視組(-6.00 D ＜屈光度).多組間比較採用方差分析,左右眼比較應用獨立樣本t檢驗,不同位點角膜厚度相關性以及角膜厚度與其他因素相關性應用Pearson相關分析.結果 458眼角膜頂點、中央、最薄點厚度平均值分彆為(529.58±22.38) μm、(529.75±22.51)μm、(527.78±22.71)μm.圍繞角膜頂點的不同直徑虛擬圓上角膜厚度最大平均值均位于90°位點,其平均值分彆為(544.14±22.07) μm、(583.15±24.72) μm、(646.27±27.34) μm、(716.52±27.70)μm.圍繞角膜頂點的2 mm、4 mm、6 mm、8 mm直徑虛擬圓上角膜厚度最小平均值分彆位于315°、315 °、337.5°、342°,其平均值分彆為(532.48±23.51) μm、(549.24±26.97) μm、(590.02±27.06) μm、(657.37±32.03) μm.左右眼角膜中央、頂點和最薄點厚度呈正相關(r=0.768、0.548、0.671,P均＜0.05).低、中、高屈光度與角膜不同區域厚度的平均值均無相關性,低、中、高屈光度組角膜厚度與切線麯率均無相關性.結論 近視眼患者角膜不同直徑虛擬圓範圍內,上方角膜厚度最厚,顳側及顳下方角膜厚度最薄.角膜厚度與屈光度和角膜前錶麵麯率均無相關性.
목적 탐토근시안환자각막불동구역후도급기차이여굴광도、곡솔지간적관계.방법 횡단면연구.근시급근시산광환자264례(458안),남122례,녀142례.응용Pentacam안전절측량분석계통대근시안각막후도진행측량분석,선취각막정점、중앙、최박점；각막후도급각막전표면절선곡솔측량균취이각막정점위중심적2 mm、4 mm、6 mm、8 mm직경허의원,이쌍안섭측수평설위0°,우안순시침、좌안역시침체증기록가사위점적각막후도평균치급각막절선곡솔평균치.의거굴광상태불동분위저도근시조(굴광도≤-3.00 D)、중도근시조(-3.00 D＜굴광도≤-6.00 D)화고도근시조(-6.00 D ＜굴광도).다조간비교채용방차분석,좌우안비교응용독립양본t검험,불동위점각막후도상관성이급각막후도여기타인소상관성응용Pearson상관분석.결과 458안각막정점、중앙、최박점후도평균치분별위(529.58±22.38) μm、(529.75±22.51)μm、(527.78±22.71)μm.위요각막정점적불동직경허의원상각막후도최대평균치균위우90°위점,기평균치분별위(544.14±22.07) μm、(583.15±24.72) μm、(646.27±27.34) μm、(716.52±27.70)μm.위요각막정점적2 mm、4 mm、6 mm、8 mm직경허의원상각막후도최소평균치분별위우315°、315 °、337.5°、342°,기평균치분별위(532.48±23.51) μm、(549.24±26.97) μm、(590.02±27.06) μm、(657.37±32.03) μm.좌우안각막중앙、정점화최박점후도정정상관(r=0.768、0.548、0.671,P균＜0.05).저、중、고굴광도여각막불동구역후도적평균치균무상관성,저、중、고굴광도조각막후도여절선곡솔균무상관성.결론 근시안환자각막불동직경허의원범위내,상방각막후도최후,섭측급섭하방각막후도최박.각막후도여굴광도화각막전표면곡솔균무상관성.
Objective To investigate the distribution of corneal thickness in myopic patients and the correlation of corneal thickness,refractive power and corneal curvature in myopia.Methods In a cross-sectional study,a total of 264 people (458 eyes) with myopia or myopic astigmatism were examined.One hundred twenty-two males and 142 females participated in the study.Corneal thickness was measured with a Pentacam system.Measurements were taken at the corneal apex,center point,thinnest point and the average value of all corneal thicknesses measured along 2 mm,4 mm,6 mm and 8 mm diameter rings with the apex location at its center.The average values for corneal thickness and curvature were recorded in an increasingly clockwise direction for the right eyes,and in a counterclockwise direction for the left eyes with the binocular temporal side set to 0°.The subjects were divided into three groups according to refractive error: the low myopia group (refractive error ＜-3.00 D),the moderate myopia group (refractive error ＞-3.00 D and ＜-6.00 D) and the high myopia group (refractive error ＞-6.00 D).ANOVA was used to analyze the differences for the three groups.The different points for corneal thickness between two groups were compared using an independent samples t test.Pearson correlation analysis was used to study the correlation of corneal thickness at different points and the relationship between corneal thickness and other factors.Results The mean values of corneal thickness at the corneal apex、center point and thinnest point were 529.58±22.38 μm,529.75±22.51 μm,and 527.78±22.7 μm.The greatest mean corneal thickness measured along the different diameter rings with the apex location at its center was always at 90 degrees and the mean values were 544.14±22.07 μm,583.15±24.72 μm,646.27±27.34 μm,and 716.52±27.70 μm.The lowest mean corneal thickness measured along the different diameter rings was at 315 degrees,315 degrees,337.5 degrees,and 342 degrees,and the values were 532.48±23.51 μm,549.24±26.97 μm,590.02±27.06 μm,and 657.37±32.03 μm.The mean values of corneal thickness at the corneal apex,center point and thinnest point were found to have a positive correlation between the left and tight eyes (r=0.768,0.548,0.671,P＜0.05).No significant correlation was found between corneal thickness and refractive error or tangential curvature (P＞O.05).Conclusion For the different diameter rings of corneal thickness in myopia,the peripheral corneal thickness values were lowest in the temporal and inferotemporal areas and greatest in the superior area.There was no relationship between corneal thickness and refractive error and corneal curvature.
