CAJ | 학술논문

目的研究频域光学相干断层扫描(OCT)信号对黄斑部视网膜厚度、容积测量的影响.方法回顾性队列研究.用Cirrus OCT对109例正常志愿者进行黄斑厚度扫描,测量黄斑部视网膜的厚度和容积.根据扫描信号将受检者分为A1组[双眼信号强度(SS)≥7]、A2组(双眼SS＜7)、B1组(双眼SS不同,均≥7)、B2组(双眼SS不同,均＜7)和B3组(一眼SS≥7,另一眼SS＜7),比较相同扫描信号两眼及不同扫描信号两眼眼底参数的差异.采用单因素方差分析和配对t检验进行分析.结果 A1组、A2组及B1组双眼黄斑部视网膜的厚度和容积差异无统计学意义.在B2组,信号较强眼的黄斑容积(CV)稍大于信号较弱眼,差异有统计学意义(t=-2.776,P＜0.05);在B3组,信号较弱眼的黄斑容积(CV)及黄斑部平均厚度(CAT)稍大于信号较强眼,差异有统计学意义(t=2.871,P＜0.05;t=3.210,P＜0.05).结论扫描信号能够影响频域OCT对黄斑部厚度及容积的测量.
목적 연구빈역광학상간단층소묘(OCT)신호대황반부시망막후도、용적측량적영향.방법 회고성대렬연구.용Cirrus OCT대109례정상지원자진행황반후도소묘,측량황반부시망막적후도화용적.근거소묘신호장수검자분위A1조[쌍안신호강도(SS)≥7]、A2조(쌍안SS＜7)、B1조(쌍안SS불동,균≥7)、B2조(쌍안SS불동,균＜7)화B3조(일안SS≥7,령일안SS＜7),비교상동소묘신호량안급불동소묘신호량안안저삼수적차이.채용단인소방차분석화배대t검험진행분석.결과 A1조、A2조급B1조쌍안황반부시망막적후도화용적차이무통계학의의.재B2조,신호교강안적황반용적(CV)초대우신호교약안,차이유통계학의의(t=-2.776,P＜0.05);재B3조,신호교약안적황반용적(CV)급황반부평균후도(CAT)초대우신호교강안,차이유통계학의의(t=2.871,P＜0.05;t=3.210,P＜0.05).결론 소묘신호능구영향빈역OCT대황반부후도급용적적측량.
Objective To investigate the effects of signal strength (SS) on the measurement of macular thickness and volume in normal volunteers with spectral-domain optical coherence tomography (OCT).Methods This was a retrospective cohort study.The retinal thickness of 109 normal volunteers was measured by a cubic scan of the macular,Cirrus OCT.All eyes were divided into subgroups:group A1 (identical SS ≥7 in both eyes),group A2 (identical SS ＜7 in both eyes),group B1 (different SS≥7 in both eyes),group B2 (different SS＜7 in both eyes) and group B3 (SS≥7 in one eye,SS＜7 in the other eye).Macular thickness and volume were measured in the subgroups.ANOVA and paired t test were used to analyze.Results There were no differences in macular thickness and volume for both eyes in group A1,group A2 and group B1.There was a significant positive correlation between SS and macular cubic volume in group B2 (t=-2.776,P＜0.05).However,there was a significant negative correlation between SS and macular cubic volume and average macular thickness in group B3 (t=2.871,P＜0.05; t=3.210,P＜0.05).Conclusion Signal strength is one of the determi-nants of macular thickness measurement with spectral-domain optical coherence tomography.