中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2013年
4期
222-225
,共4页
谭维娜%华焱军%潘超%陈佳%王勤美
譚維娜%華焱軍%潘超%陳佳%王勤美
담유나%화염군%반초%진가%왕근미
近视%角膜曲率%角膜厚度%双眼差异性%Pentacam
近視%角膜麯率%角膜厚度%雙眼差異性%Pentacam
근시%각막곡솔%각막후도%쌍안차이성%Pentacam
Myopia%Keratometry%Corneal thickness%Interocular asymmetry%Pentacam
目的 评估近视人群双眼角膜各参数的差异性,并计算差值的医学参考值范围,为临床实践提供依据.方法 横断面研究.210例近视患者(420眼),平均年龄为(24.8±0.4)岁,右眼等效球镜度为(-4.96±0.14)D,左眼等效球镜度为(-4.94±0.14)D.应用Pentacam眼前节全景仪进行测量,记录双眼平均角膜屈光力(Km),中央角膜厚度(CCT),最薄点角膜厚度(TCT),以顶点为中心的最薄点的水平坐标值(X)、垂直坐标值(Y),最薄点与顶点的距离(√(X2+Y2)).配对t检验评估双眼角膜各参数的差异;Pearson相关分析双眼角膜各参数的相关性;采用第95％分位数或均数加2倍的标准差((x)+2s)描述双眼角膜各参数差值的医学参考值范围.结果 双眼角膜Km、CCT、TCT、最薄点与顶点的距离√(X2+Y2)差异均没有统计学意义(t=-1.38、1.44、1.25、1.87,P均＞0.05);双眼以顶点为中心的最薄点的水平坐标值(X)、垂直坐标值(Y)差异有统计学意义(t=-33.92、8.95,P均＜0.01).双眼角膜Km,CCT,TCT,以顶点为中心的最薄点的水平坐标值X、垂直坐标值Y,最薄点与顶点的距离√(X2+Y2)差值的95％医学参考值范围上限分别为0.5 D、13.67 μm、12.83 μm、1.52 mm、0.32 mm、0.30 mm.结论 Pentacam获得的近视人群双眼角膜各参数相近,但仍具有一定差异性,而这些角膜参数差值的医学参考值范围可能为眼科相关疾病(如青光眼、角膜扩张性疾病等)的诊断和筛查提供指导.
目的 評估近視人群雙眼角膜各參數的差異性,併計算差值的醫學參攷值範圍,為臨床實踐提供依據.方法 橫斷麵研究.210例近視患者(420眼),平均年齡為(24.8±0.4)歲,右眼等效毬鏡度為(-4.96±0.14)D,左眼等效毬鏡度為(-4.94±0.14)D.應用Pentacam眼前節全景儀進行測量,記錄雙眼平均角膜屈光力(Km),中央角膜厚度(CCT),最薄點角膜厚度(TCT),以頂點為中心的最薄點的水平坐標值(X)、垂直坐標值(Y),最薄點與頂點的距離(√(X2+Y2)).配對t檢驗評估雙眼角膜各參數的差異;Pearson相關分析雙眼角膜各參數的相關性;採用第95％分位數或均數加2倍的標準差((x)+2s)描述雙眼角膜各參數差值的醫學參攷值範圍.結果 雙眼角膜Km、CCT、TCT、最薄點與頂點的距離√(X2+Y2)差異均沒有統計學意義(t=-1.38、1.44、1.25、1.87,P均＞0.05);雙眼以頂點為中心的最薄點的水平坐標值(X)、垂直坐標值(Y)差異有統計學意義(t=-33.92、8.95,P均＜0.01).雙眼角膜Km,CCT,TCT,以頂點為中心的最薄點的水平坐標值X、垂直坐標值Y,最薄點與頂點的距離√(X2+Y2)差值的95％醫學參攷值範圍上限分彆為0.5 D、13.67 μm、12.83 μm、1.52 mm、0.32 mm、0.30 mm.結論 Pentacam穫得的近視人群雙眼角膜各參數相近,但仍具有一定差異性,而這些角膜參數差值的醫學參攷值範圍可能為眼科相關疾病(如青光眼、角膜擴張性疾病等)的診斷和篩查提供指導.
목적 평고근시인군쌍안각막각삼수적차이성,병계산차치적의학삼고치범위,위림상실천제공의거.방법 횡단면연구.210례근시환자(420안),평균년령위(24.8±0.4)세,우안등효구경도위(-4.96±0.14)D,좌안등효구경도위(-4.94±0.14)D.응용Pentacam안전절전경의진행측량,기록쌍안평균각막굴광력(Km),중앙각막후도(CCT),최박점각막후도(TCT),이정점위중심적최박점적수평좌표치(X)、수직좌표치(Y),최박점여정점적거리(√(X2+Y2)).배대t검험평고쌍안각막각삼수적차이;Pearson상관분석쌍안각막각삼수적상관성;채용제95％분위수혹균수가2배적표준차((x)+2s)묘술쌍안각막각삼수차치적의학삼고치범위.결과 쌍안각막Km、CCT、TCT、최박점여정점적거리√(X2+Y2)차이균몰유통계학의의(t=-1.38、1.44、1.25、1.87,P균＞0.05);쌍안이정점위중심적최박점적수평좌표치(X)、수직좌표치(Y)차이유통계학의의(t=-33.92、8.95,P균＜0.01).쌍안각막Km,CCT,TCT,이정점위중심적최박점적수평좌표치X、수직좌표치Y,최박점여정점적거리√(X2+Y2)차치적95％의학삼고치범위상한분별위0.5 D、13.67 μm、12.83 μm、1.52 mm、0.32 mm、0.30 mm.결론 Pentacam획득적근시인군쌍안각막각삼수상근,단잉구유일정차이성,이저사각막삼수차치적의학삼고치범위가능위안과상관질병(여청광안、각막확장성질병등)적진단화사사제공지도.
Objective To compare the corneal parameters of the two eyes in a myopia population and to establish the normal range of interocular differences for clinical examination and diagnosis.Methods In this cross-sectional study,210 patients (420 eyes) whose mean age was 24.8±0.4 years,average spherical equivalents were-4.96±0.14 D in right eyes and-4.94±0.14 D in left eyes,were measured by Pentacam.Corneal parameters,including mean keratometry Km,central corneal thickness (CCT),thinnest corneal thickness (TCT),the location of the thinnest points (X,Y) and the distance from the thinnest to central corneal points （√(X2+Y2）) and the interocular differences were recorded.A paired t test was used to assess the differences between the two eyes' corneal parameters and a Pearson correlation was used to describe their linear relationship.The normal range of interocular differences was described by the 95th percentile or mean+2 standard deviation (SD).Results No statistically significant binocular differences were found in Km (t=-1.38,P＞0.05),CCT (t=1.44,P＞0.05),TCT (t=1.25,P＞O.05),√（X2+Y2）(t=1.87,P＞0.05) except X (t=-33.92,P＜0.01) and Y (t=8.95,P＜0.O1).Less than 5％ of the sample had differences greater than 0.5 D in Km,13.67 μm in CCT,12.83 μm in TCT,1.52 mm in the vertical location of the thinnest points,0.32 mm in the horizontal location of the thinnest points,or 0.30 mm in the distance from the thinnest to central corneal points between eyes.Conclusion Binocular corneal parameters have some differences.The normal range of binocular differences can provide a guide for intraocular lens power calculation,clinical diagnosis and screening of glaucoma and corneal ectasia disease.
