中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2013年
7期
405-408
,共4页
董子献%周行涛%赵振南%章哲环%李涛%徐海鹏
董子獻%週行濤%趙振南%章哲環%李濤%徐海鵬
동자헌%주행도%조진남%장철배%리도%서해붕
飞秒激光%角膜磨镶术,激光原位%体层摄影术,光学相干%视网膜神经纤维层
飛秒激光%角膜磨鑲術,激光原位%體層攝影術,光學相榦%視網膜神經纖維層
비초격광%각막마양술,격광원위%체층섭영술,광학상간%시망막신경섬유층
Femtosecond laser%Keratomileusis,laser in situ%Tomography,optical coherence%Retinal nerve fiber layer
目的 比较飞秒激光准分子激光原位角膜磨镶术(LASIK)前后视网膜神经纤维层(RNFL)厚度和黄斑区视网膜参数的变化.方法 前瞻性连续病例研究.选择接受飞秒激光LASIK术的高度近视眼患者17例(33眼)(等效球镜度＞-6.00 D),采用RTVue-100频域光学相干断层成像仪(OCT)观察术眼术前、术后1d、1周及1个月时RNFL厚度以及黄斑厚度和容积变化.采用单因素方差分析比较手术前后测量参数的变化.结果 RNFL厚度(全部、颞侧、上方、鼻侧、下方)术前与术后各时间点差异无统计学意义(F=0.003、0.503、0.285、0.164、0.277,P＞0.05).黄斑区(包括中心凹、旁中心凹、颞侧、上方、鼻侧、下方)视网膜厚度(F=0.491、0.281、0.234、0.341、0.614、0.192,P＞0.05)及容积(F=0.484、0.968、0.200、0.314、0.622、0.206,P＞0.05)术前与术后1d、1周、1个月各时间点差异均无统计学意义.结论 飞秒激光LASIK手术对RNFL厚度和黄斑区视网膜参数无明显影响.
目的 比較飛秒激光準分子激光原位角膜磨鑲術(LASIK)前後視網膜神經纖維層(RNFL)厚度和黃斑區視網膜參數的變化.方法 前瞻性連續病例研究.選擇接受飛秒激光LASIK術的高度近視眼患者17例(33眼)(等效毬鏡度＞-6.00 D),採用RTVue-100頻域光學相榦斷層成像儀(OCT)觀察術眼術前、術後1d、1週及1箇月時RNFL厚度以及黃斑厚度和容積變化.採用單因素方差分析比較手術前後測量參數的變化.結果 RNFL厚度(全部、顳側、上方、鼻側、下方)術前與術後各時間點差異無統計學意義(F=0.003、0.503、0.285、0.164、0.277,P＞0.05).黃斑區(包括中心凹、徬中心凹、顳側、上方、鼻側、下方)視網膜厚度(F=0.491、0.281、0.234、0.341、0.614、0.192,P＞0.05)及容積(F=0.484、0.968、0.200、0.314、0.622、0.206,P＞0.05)術前與術後1d、1週、1箇月各時間點差異均無統計學意義.結論 飛秒激光LASIK手術對RNFL厚度和黃斑區視網膜參數無明顯影響.
목적 비교비초격광준분자격광원위각막마양술(LASIK)전후시망막신경섬유층(RNFL)후도화황반구시망막삼수적변화.방법 전첨성련속병례연구.선택접수비초격광LASIK술적고도근시안환자17례(33안)(등효구경도＞-6.00 D),채용RTVue-100빈역광학상간단층성상의(OCT)관찰술안술전、술후1d、1주급1개월시RNFL후도이급황반후도화용적변화.채용단인소방차분석비교수술전후측량삼수적변화.결과 RNFL후도(전부、섭측、상방、비측、하방)술전여술후각시간점차이무통계학의의(F=0.003、0.503、0.285、0.164、0.277,P＞0.05).황반구(포괄중심요、방중심요、섭측、상방、비측、하방)시망막후도(F=0.491、0.281、0.234、0.341、0.614、0.192,P＞0.05)급용적(F=0.484、0.968、0.200、0.314、0.622、0.206,P＞0.05)술전여술후1d、1주、1개월각시간점차이균무통계학의의.결론 비초격광LASIK수술대RNFL후도화황반구시망막삼수무명현영향.
Objective To evaluate the changes of retinal nerve fiber layer and macular parameters after femtosecond laser-assisted laser in situ keratomileusis (fs-LASIK) assessed by spectral-domain optical coherence tomography (SD-OCT).Methods This prospective,consecutive study included 17 patients (33 eyes) with high (greater than-6.00 D) myopia treated with fs-LASIK.The macular thickness and volume and RNFLT measurements were performed using RTVue-100 OCT preoperatively and then on 1 day,1 week and 1 month postoperation.The measurements before and after fs-LASIK were compared using one-way analysis of variance (ANOVA).Results None of the RNFL parameters of whole,temporal,upper,nasal and below were observed to have a statistically significant change after fs-LASIK surgery (F=0.003,0.503,0.285,0.164,0.277,P＞0.05).Also,there was no statistically significant difference in macular thickness (F=0.491,0.281,0.234,0.341,0.614,0.192,P＞0.05) and volum (F=0.484,0.968,0.200,0.314,0.622,0.206,P＞0.05) of central fovea,parafovea,temporal,upper,nasal and below between pre-and postoperatively.Conclusion Femtosecond laser-assisted laser in situ keratomileusis has no significant effect on retinal nerve fiber layer and macular parameters determined by SD-OCT.
