中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
4期
196-199
,共4页
王璐%王雁%左彤%耿维莉%金颖%祖培培%张慧
王璐%王雁%左彤%耿維莉%金穎%祖培培%張慧
왕로%왕안%좌동%경유리%금영%조배배%장혜
飞秒激光%角膜磨镶术,激光原位%像差%波前优化%近视
飛秒激光%角膜磨鑲術,激光原位%像差%波前優化%近視
비초격광%각막마양술,격광원위%상차%파전우화%근시
Femtosecond laser%Keratomileusis,laser in situ%Aberration%Wavefront optimized%Myopia
目的 研究飞秒激光制瓣LASIK(飞秒LASIK)联合波前优化治疗近视及散光术后角膜像差的特性.方法 回顾性研究.行飞秒LASIK手术的近视及近视散光患者30例(30眼),平均年龄(20.9±2.8)岁;术前平均等效球镜度(-6.48±1.61)D.应用Pentacam眼前节分析仪测量角膜前表面6、7、8、9 mm直径下的Q值,采用Keratron角膜波前像差分析仪测量6 mm瞳孔直径下角膜波前像差.随访时间为术后3个月,手术前后数据采用配对t检验,采用Pearson相关分析角膜像差、Q值与其他参数的相关性.结果 6 mm瞳孔直径下角膜高阶像差、总球差、总彗差、水平彗差、垂直彗差、初级球差、x-向次级像散、次级水平彗差、次级垂直彗差、次级球差均较术前增加,差异有统计学意义(t=-8.254、-7.385、-6.108、-5.651、-2.195、-7.565、-4.628、-2.974、-2.748、-7.068,P＜0.05).角膜前表面4个直径范围内Q值均较术前增加,差异有统计学意义(t=16.999、-19.208、-21.502、-22.197,P＜0.05).6 mm瞳孔直径下手术前后Q值变化量(△Q6mm)与高阶像差变化量、总球差变化量、初级球差变化量、总彗差变化量呈正相关(r=0.736、0.792、0.788、0.383,P＜0.05),△Q6mm与总三叶草变化量、次级球差变化量无相关性(r=0.099、-0.348,P＞0.05).结论 飞秒LASIK联合波前优化治疗近视及近视散光是安全、有效的,但术后角膜高阶像差仍有显著增加.
目的 研究飛秒激光製瓣LASIK(飛秒LASIK)聯閤波前優化治療近視及散光術後角膜像差的特性.方法 迴顧性研究.行飛秒LASIK手術的近視及近視散光患者30例(30眼),平均年齡(20.9±2.8)歲;術前平均等效毬鏡度(-6.48±1.61)D.應用Pentacam眼前節分析儀測量角膜前錶麵6、7、8、9 mm直徑下的Q值,採用Keratron角膜波前像差分析儀測量6 mm瞳孔直徑下角膜波前像差.隨訪時間為術後3箇月,手術前後數據採用配對t檢驗,採用Pearson相關分析角膜像差、Q值與其他參數的相關性.結果 6 mm瞳孔直徑下角膜高階像差、總毬差、總彗差、水平彗差、垂直彗差、初級毬差、x-嚮次級像散、次級水平彗差、次級垂直彗差、次級毬差均較術前增加,差異有統計學意義(t=-8.254、-7.385、-6.108、-5.651、-2.195、-7.565、-4.628、-2.974、-2.748、-7.068,P＜0.05).角膜前錶麵4箇直徑範圍內Q值均較術前增加,差異有統計學意義(t=16.999、-19.208、-21.502、-22.197,P＜0.05).6 mm瞳孔直徑下手術前後Q值變化量(△Q6mm)與高階像差變化量、總毬差變化量、初級毬差變化量、總彗差變化量呈正相關(r=0.736、0.792、0.788、0.383,P＜0.05),△Q6mm與總三葉草變化量、次級毬差變化量無相關性(r=0.099、-0.348,P＞0.05).結論 飛秒LASIK聯閤波前優化治療近視及近視散光是安全、有效的,但術後角膜高階像差仍有顯著增加.
목적 연구비초격광제판LASIK(비초LASIK)연합파전우화치료근시급산광술후각막상차적특성.방법 회고성연구.행비초LASIK수술적근시급근시산광환자30례(30안),평균년령(20.9±2.8)세;술전평균등효구경도(-6.48±1.61)D.응용Pentacam안전절분석의측량각막전표면6、7、8、9 mm직경하적Q치,채용Keratron각막파전상차분석의측량6 mm동공직경하각막파전상차.수방시간위술후3개월,수술전후수거채용배대t검험,채용Pearson상관분석각막상차、Q치여기타삼수적상관성.결과 6 mm동공직경하각막고계상차、총구차、총혜차、수평혜차、수직혜차、초급구차、x-향차급상산、차급수평혜차、차급수직혜차、차급구차균교술전증가,차이유통계학의의(t=-8.254、-7.385、-6.108、-5.651、-2.195、-7.565、-4.628、-2.974、-2.748、-7.068,P＜0.05).각막전표면4개직경범위내Q치균교술전증가,차이유통계학의의(t=16.999、-19.208、-21.502、-22.197,P＜0.05).6 mm동공직경하수술전후Q치변화량(△Q6mm)여고계상차변화량、총구차변화량、초급구차변화량、총혜차변화량정정상관(r=0.736、0.792、0.788、0.383,P＜0.05),△Q6mm여총삼협초변화량、차급구차변화량무상관성(r=0.099、-0.348,P＞0.05).결론 비초LASIK연합파전우화치료근시급근시산광시안전、유효적,단술후각막고계상차잉유현저증가.
Objective To evaluate the corneal aberrations after femtosecond LASIK for myopia and myopia astigmatism with a wavefront optimized profile.Methods Prospective study including 30 eyes from 30 patients (mean 20.9±2.8 years) with myopia (mean spherical equivalent refractive -6.48±1.61 D).The asphericity (Q value) of the anterior corneal surface for patients with different corneal diameters (6,7,8 and 9 mm) were measured with Pentacam.Higher-order aberrations (HOAs) of the corneal were measured with the Keratron at 6 mm pupil diameter.Postoperative changes in corneal HOAs and corneal asphericity were analyzed during 3 months follow up.Paired t test was used to analysis the pre-and post-operative data.Pearson correlation was used to investigate correlations between Q values,corneal aberrations and other data.Results At 6 mm pupil diameter significant increases in corneal HOAs,whole spherical aberration (WsA),whole coma (WComa),C3+1,C3-1,C40、C4+2,C5+1,C5-1,C60 were observed 3 months after surgery (t=-8.254,-7.385,-5.108,-5.651,-2.195,-7.565,-4.628,-2.974,-2.748,-7.068,P＜0.05).Corneal asphericity for 6,7,8,9 mm also increased significantly (t=16.999,-19.208,-21.502,22.197,P＜0.05).At 6 mm pupil diameter significant correlations were found between Q change (△Q6mm) and HOA change (△HOA),WSA change (△WsA),C40 change (△C40),WCom change (△WComa) (r=0.736,0.792,0.788,0.383,P＜0.05).No correlation between △Q6 mm and whole trefoil change (△WTrefoil),C60 change (△C60)(r=0.099,-0.348,P＞0.05).Conclusion Femtosecond LASIK using a wavefront optimized ablation profile yielded excellent visual outcomes.A significant induction of corneal HOAs still exists.
