中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
6期
350-353
,共4页
李敏%程慧勤%苑影%王佳%柯碧莲
李敏%程慧勤%苑影%王佳%柯碧蓮
리민%정혜근%원영%왕가%가벽련
近视%脉络膜厚度%眼压%屈光不正
近視%脈絡膜厚度%眼壓%屈光不正
근시%맥락막후도%안압%굴광불정
Myopia%Choroidal thickness%Intraocular pressure%Refractive error
目的 探讨近视人群脉络膜厚度(CT)与屈光度数及眼压的关系.方法 横断面研究.使用频域OCT测量118例近视患者黄斑中心凹及距中心凹0.5、1.0、2.5 mm的颞侧、鼻侧、上方、下方CT,采用非接触眼压计测量眼压,记录等效球镜度,取右眼数据进行单因素方差分析、相关性分析、多元线性回归分析.结果 距离中心凹1.0、2.5 mm的鼻侧脉络膜显著薄于黄斑中心凹及其余3个方位(P＜0.01).黄斑中心凹、距离中心凹0.5 mm和1.0 mm的4个方位CT与等效球镜度均呈负相关(r=-0.330、-0.207、-0.205、-0.272、-0.317、-0.283、-0.269、-0.212、-0.252,P＜0.05);距离黄斑中心凹2.5 mm的4个方位CT与等效球镜度不相关.距离黄斑中心凹2.5 mm的鼻侧CT与眼压不相关,其余各位点的CT均与眼压呈负相关(r=-0.295、-0.358、-0.459、-0.675、-0.315 、-0.285、-0.314 、-0.322、-0.295、-0.392、-0.336、-0.317,P＜0.01).通过多元线性回归,建立如下方程:黄斑中心凹下CT(μm)=345.22-4.54×眼压(mmHg)-7.57×等效球镜度数(D) (F=12.51,P＜0.01).结论 黄斑中心凹及靠近中心凹的各位点的CT随着屈光度数增加而变薄,远离中心凹的CT未受影响.大部分位点的CT随着眼压降低而增厚.
目的 探討近視人群脈絡膜厚度(CT)與屈光度數及眼壓的關繫.方法 橫斷麵研究.使用頻域OCT測量118例近視患者黃斑中心凹及距中心凹0.5、1.0、2.5 mm的顳側、鼻側、上方、下方CT,採用非接觸眼壓計測量眼壓,記錄等效毬鏡度,取右眼數據進行單因素方差分析、相關性分析、多元線性迴歸分析.結果 距離中心凹1.0、2.5 mm的鼻側脈絡膜顯著薄于黃斑中心凹及其餘3箇方位(P＜0.01).黃斑中心凹、距離中心凹0.5 mm和1.0 mm的4箇方位CT與等效毬鏡度均呈負相關(r=-0.330、-0.207、-0.205、-0.272、-0.317、-0.283、-0.269、-0.212、-0.252,P＜0.05);距離黃斑中心凹2.5 mm的4箇方位CT與等效毬鏡度不相關.距離黃斑中心凹2.5 mm的鼻側CT與眼壓不相關,其餘各位點的CT均與眼壓呈負相關(r=-0.295、-0.358、-0.459、-0.675、-0.315 、-0.285、-0.314 、-0.322、-0.295、-0.392、-0.336、-0.317,P＜0.01).通過多元線性迴歸,建立如下方程:黃斑中心凹下CT(μm)=345.22-4.54×眼壓(mmHg)-7.57×等效毬鏡度數(D) (F=12.51,P＜0.01).結論 黃斑中心凹及靠近中心凹的各位點的CT隨著屈光度數增加而變薄,遠離中心凹的CT未受影響.大部分位點的CT隨著眼壓降低而增厚.
목적 탐토근시인군맥락막후도(CT)여굴광도수급안압적관계.방법 횡단면연구.사용빈역OCT측량118례근시환자황반중심요급거중심요0.5、1.0、2.5 mm적섭측、비측、상방、하방CT,채용비접촉안압계측량안압,기록등효구경도,취우안수거진행단인소방차분석、상관성분석、다원선성회귀분석.결과 거리중심요1.0、2.5 mm적비측맥락막현저박우황반중심요급기여3개방위(P＜0.01).황반중심요、거리중심요0.5 mm화1.0 mm적4개방위CT여등효구경도균정부상관(r=-0.330、-0.207、-0.205、-0.272、-0.317、-0.283、-0.269、-0.212、-0.252,P＜0.05);거리황반중심요2.5 mm적4개방위CT여등효구경도불상관.거리황반중심요2.5 mm적비측CT여안압불상관,기여각위점적CT균여안압정부상관(r=-0.295、-0.358、-0.459、-0.675、-0.315 、-0.285、-0.314 、-0.322、-0.295、-0.392、-0.336、-0.317,P＜0.01).통과다원선성회귀,건립여하방정:황반중심요하CT(μm)=345.22-4.54×안압(mmHg)-7.57×등효구경도수(D) (F=12.51,P＜0.01).결론 황반중심요급고근중심요적각위점적CT수착굴광도수증가이변박,원리중심요적CT미수영향.대부분위점적CT수착안압강저이증후.
Objective To investigate the relationship between choroidal thickness (CT) and equivalent power and intraocular pressure (IOP) in a myopic Chinese population.Methods This cross-sectional study included 118 myopic patients.Choroidal thickness was measured at the fovea and 0.5,1.0 and 2.5 mm temporal,nasal,superior,and inferior to the fovea using spectral-domain OCT.IOP was measured with a non-contact tonometer.Refractive error was described as equivalent power.The data of the right eyes were analyzed with a one-way ANOVA,correlation analysis,and linear regression analysis.Results CT at 1.0 and 2.5 mm nasal to the fovea was thinner than CT at the fovea and the three other directions (P＜0.01).CT at the fovea and 0.5 and 1.0 mm temporal,nasal,superior,and inferior to the fovea were negatively correlated with equivalent power (r=-0.330,-0.207,-0.205,-0.272,-0.317,-0.283,-0.269,-0.212,-0.252; P＜0.05).No correlation was found between equivalent power and CT at 2.5 mm temporal,nasal,superior,and inferior to the fovea.There was no correlation between CT at 2.5 mm nasal to the fovea and IOP.CT at other locations was negatively correlated with IOP (r=-0.295,-0.358,-0.459,-0.675,-0.315,-0.285,-0.314,-0.322,-0.295,-0.392,-0.336,-0.317; P＜0.01).The formula obtained with multiple linear regression analysis was as follows:CT at the fovea (μm)=345.22-4.54×IOP (mmHg)-7.57× equivalent power (D) (F=12.51,P＜0.01).Condnsion CT at the fovea and close to the fovea became thinner as equivalent power increased,but CT away from the fovea was not affected by equivalent power.CT at most locations became thicker as IOP decreased.
