中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
7期
446-448
,共3页
交感性眼炎%免疫机制%治疗
交感性眼炎%免疫機製%治療
교감성안염%면역궤제%치료
Sympathetic ophthalmia%Immunologic mechanism%Treatment
交感性眼炎是一眼发生眼球穿通伤或内眼手术后引起的双眼非坏死性肉芽肿性葡萄膜炎.可隐匿发病也可急性发病.交感性眼炎临床表现多变,病情易于反复恶化,并可能致盲.典型的临床表现为羊脂状角膜后沉着物,脉络膜渗出及Dalen-Fuchs结节.组织学上表现为弥漫性或肉芽肿性葡萄膜炎症反应.目前的治疗包括药物治疗及手术治疗.发病机制目前尚未完全清楚,多认为是激发眼引起的自身免疫反应导致交感眼发病.
交感性眼炎是一眼髮生眼毬穿通傷或內眼手術後引起的雙眼非壞死性肉芽腫性葡萄膜炎.可隱匿髮病也可急性髮病.交感性眼炎臨床錶現多變,病情易于反複噁化,併可能緻盲.典型的臨床錶現為羊脂狀角膜後沉著物,脈絡膜滲齣及Dalen-Fuchs結節.組織學上錶現為瀰漫性或肉芽腫性葡萄膜炎癥反應.目前的治療包括藥物治療及手術治療.髮病機製目前尚未完全清楚,多認為是激髮眼引起的自身免疫反應導緻交感眼髮病.
교감성안염시일안발생안구천통상혹내안수술후인기적쌍안비배사성육아종성포도막염.가은닉발병야가급성발병.교감성안염림상표현다변,병정역우반복악화,병가능치맹.전형적림상표현위양지상각막후침착물,맥락막삼출급Dalen-Fuchs결절.조직학상표현위미만성혹육아종성포도막염증반응.목전적치료포괄약물치료급수술치료.발병궤제목전상미완전청초,다인위시격발안인기적자신면역반응도치교감안발병.
Sympathetic ophthalmia is a rare bilateral granulomatous inflammation that follows accidental or surgical insult to the uvea of one eye.Onset of sympathetic ophthalmia can be insidious or acute,with variable clinical manifestations.Sympathetic ophthalmia can deteriorate repeatedly and induce blindness.Clinical presentation shows mutton-fat keratic precipitates,choroidal infiltrations,and Dalen-Fuchs nodules.Histopathology reveals diffuse or nodular granulomatous inflammation of the uvea.Prevention and treatment strategies for sympathetic ophthalmia include medicine and surgery.The mechanism of the disease is still unclear but is largely thought to be autoimmune in nature.