中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2014年
10期
599-603
,共5页
戴冬姝%刘玉青%王志学%李静%陈默%冯桂银
戴鼕姝%劉玉青%王誌學%李靜%陳默%馮桂銀
대동주%류옥청%왕지학%리정%진묵%풍계은
青光眼引流植入物%青光眼%眼内压%治疗结果
青光眼引流植入物%青光眼%眼內壓%治療結果
청광안인류식입물%청광안%안내압%치료결과
Glaucoma drainage implant%Glaucoma%Intraocular pressure%Treatment outcome
目的 比较FP-7型与S2型Ahmed青光眼引流阀治疗难治性青光眼的疗效及并发症有无差异.方法 回顾性病例研究.分析于沧州市中心医院眼科分别行S2型(26例26眼)和FP-7型(23例23眼)Ahmed青光眼引流阀植入术的难治性青光眼患者的临床资料,对2组的眼压变化、手术成功率、术后并发症等进行比较.术前、术后眼压比较及2个观察组降眼压效果比较采用重复测量资料的方差分析;手术成功率的计算采用寿命表法,比较采用log-rank检验;并发症发生率的比较采用Fisher确切概率法.结果 S2组术前眼压为(38.19±10.56)mmHg,术后1、6、12、24个月的眼压分别为(14.54±4.11)mmHg、(15.83±5.76)mmHg、(17.19±4.96)mmHg、(18.84±5.28)mmHg; FP-7组术前眼压为(39.91 ±9.12)mmHg,术后各时间点眼压分别为(14.41±5.14)mmHg、(15.95±4.32)mmHg、(17.11±4.75)mmHg、(19.06±6.55)mmHg.2组降眼压效果差异无统计学意义.至最后一次随访S2组的累积总成功率和累积完全成功率分别为82%和74%,FP-7组分别为80%和75%,2组比较差异无统计学意义.结论 FP-7型与S2型Ahmed青光眼引流阀治疗难治性青光眼的降眼压效果相当,FP-7型的术后并发症发生率不高于S2型.
目的 比較FP-7型與S2型Ahmed青光眼引流閥治療難治性青光眼的療效及併髮癥有無差異.方法 迴顧性病例研究.分析于滄州市中心醫院眼科分彆行S2型(26例26眼)和FP-7型(23例23眼)Ahmed青光眼引流閥植入術的難治性青光眼患者的臨床資料,對2組的眼壓變化、手術成功率、術後併髮癥等進行比較.術前、術後眼壓比較及2箇觀察組降眼壓效果比較採用重複測量資料的方差分析;手術成功率的計算採用壽命錶法,比較採用log-rank檢驗;併髮癥髮生率的比較採用Fisher確切概率法.結果 S2組術前眼壓為(38.19±10.56)mmHg,術後1、6、12、24箇月的眼壓分彆為(14.54±4.11)mmHg、(15.83±5.76)mmHg、(17.19±4.96)mmHg、(18.84±5.28)mmHg; FP-7組術前眼壓為(39.91 ±9.12)mmHg,術後各時間點眼壓分彆為(14.41±5.14)mmHg、(15.95±4.32)mmHg、(17.11±4.75)mmHg、(19.06±6.55)mmHg.2組降眼壓效果差異無統計學意義.至最後一次隨訪S2組的纍積總成功率和纍積完全成功率分彆為82%和74%,FP-7組分彆為80%和75%,2組比較差異無統計學意義.結論 FP-7型與S2型Ahmed青光眼引流閥治療難治性青光眼的降眼壓效果相噹,FP-7型的術後併髮癥髮生率不高于S2型.
목적 비교FP-7형여S2형Ahmed청광안인류벌치료난치성청광안적료효급병발증유무차이.방법 회고성병례연구.분석우창주시중심의원안과분별행S2형(26례26안)화FP-7형(23례23안)Ahmed청광안인류벌식입술적난치성청광안환자적림상자료,대2조적안압변화、수술성공솔、술후병발증등진행비교.술전、술후안압비교급2개관찰조강안압효과비교채용중복측량자료적방차분석;수술성공솔적계산채용수명표법,비교채용log-rank검험;병발증발생솔적비교채용Fisher학절개솔법.결과 S2조술전안압위(38.19±10.56)mmHg,술후1、6、12、24개월적안압분별위(14.54±4.11)mmHg、(15.83±5.76)mmHg、(17.19±4.96)mmHg、(18.84±5.28)mmHg; FP-7조술전안압위(39.91 ±9.12)mmHg,술후각시간점안압분별위(14.41±5.14)mmHg、(15.95±4.32)mmHg、(17.11±4.75)mmHg、(19.06±6.55)mmHg.2조강안압효과차이무통계학의의.지최후일차수방S2조적루적총성공솔화루적완전성공솔분별위82%화74%,FP-7조분별위80%화75%,2조비교차이무통계학의의.결론 FP-7형여S2형Ahmed청광안인류벌치료난치성청광안적강안압효과상당,FP-7형적술후병발증발생솔불고우S2형.
Objective To compare the efficacy of using of FP-7 and S2 Ahmed glaucoma valve implantations (AGI) for refractory glaucoma and to monitor postoperative complications.Methods A retrospective study was conducted to document patients with refractory glaucoma who underwent S2 (26 eyes from 26 patients) or FP-7 (23 eyes from 23 patients) AGI in the Center Hospital of Cangzhou.The change in IOP,the surgical success rate,and postoperative complications were recorded and analyzed.A variance analysis of repeated measurement data was used for comparison of preoperative and postoperative IOP and the effect of reducing IOP in the 2 observation groups.Cumulative survival rates were calculated using survival analysis and compared using a log-rank.The Fisher exact test was used for the comparison of complication rates.Results IOP was reduced from 38.19±10.56 mmHg to 14.54±4.11,15.83±5.76,17.19±4.96,and 18.84±5.28 mmHg at month 1,month 6,month 12,and month 24 postoperatively in the S2 group and reduced from 39.91±9.12 mmHg to 14.41±5.14,15.95±4.32,17.11±4.75,and 19.06±6.55 mmHg in the FP-7 group.There was no statistically significant difference between the 2 groups for their effect on lowering IOP.At the last follow-up,the cumulative probabilities of success and of total success were 82% and 74% in the S2 group,and 80% and 75% in the FP-7 group.There was no statistically significant difference between the 2 groups.Conclusion FP-7 AGI was equal to S2 AGI in reducing IOP in refractory glaucoma.The complication rate in the S2 group was no higher than it was in the FP-7 group.