CAJ | 학술논문

目的探讨经湿化高流量鼻导管通气(HHFNC)在新生儿肺透明膜病中的临床应用效果.方法 66例诊断为Ⅰ～Ⅱ级新生儿肺透明膜病的早产儿采用经湿化高流量鼻导管通气(HHFNC)治疗,观察治疗前后临床症状和血气指标.初始参数设置:Flow 2～8 L/min,FiO2 0.21～0.40.观察记录患儿治疗后72 h的临床情况:若患儿血气分析PaCO2＞65 mmHg,FiO2＞0.5;出现严重呼吸暂停(1h内出现3次伴有心率减慢的呼吸暂停,或出现1次呼吸暂停需要正压通气)考虑为使用该辅助呼吸支持模式治疗失败,需气管插管机械辅助通气.结果 66例患儿中,59例经治疗后顺利撤除HHFNC,另外7例需转为气管插管机械辅助通气.结论经湿化高流量鼻导管通气(HHFNC)能对轻度新生儿肺透明膜病进行呼吸支持,改善其低氧血症.
목적 탐토경습화고류량비도관통기(HHFNC)재신생인폐투명막병중적림상응용효과.방법 66례진단위Ⅰ～Ⅱ급신생인폐투명막병적조산인채용경습화고류량비도관통기(HHFNC)치료,관찰치료전후림상증상화혈기지표.초시삼수설치:Flow 2～8 L/min,FiO2 0.21～0.40.관찰기록환인치료후72 h적림상정황:약환인혈기분석PaCO2＞65 mmHg,FiO2＞0.5;출현엄중호흡잠정(1h내출현3차반유심솔감만적호흡잠정,혹출현1차호흡잠정수요정압통기)고필위사용해보조호흡지지모식치료실패,수기관삽관궤계보조통기.결과 66례환인중,59례경치료후순리철제HHFNC,령외7례수전위기관삽관궤계보조통기.결론 경습화고류량비도관통기(HHFNC)능대경도신생인폐투명막병진행호흡지지,개선기저양혈증.
Objective To explore the clinical effects of heated humidified high-flow nasal cannula (HHFNC) in treating neonatal hyaline membrane disease (NHMD).Methods 66 infants were diagnosed as mild NHMD according clinical findings and chest X-ray.HHFNC was used after building diagnosis.We adjusted HHFNC parameter according patients' arterial blood gas.Results 59 of 66 patients were fully recovered using HHFNC treatment.7 patients were incubated and used mechanical ventilation.Conclusion HHFNC is an available and effective treatment method for mild NHMD and provide respiratory support,and can improve hyoxemia symptoms.