CAJ | 학술논문

目的研究自血疗法联合卡介菌多糖核酸治疗面部激素依赖性皮炎的临床疗效及安全性.方法将74例面部激素依赖性皮炎患者按治疗方法不同分为治疗组(38例)和对照组(36例),治疗组采用自血疗法联合卡介菌多糖核酸1ml肌肉注射,3d1次,4周为1个疗程,对照组采用卡介菌多糖核酸1ml肌肉注射,3d1次,4周为1个疗程.比较两组疗效.结果治疗组总有效率为84.2％(32/38),对照组为63.9％(23/36),两组比较差异有统计学意义(P＜0.05).两组患者均无严重不良反应发生.结论自血疗法联合卡介菌多糖核酸治疗面部激素依赖性皮炎安全有效.
목적 연구자혈요법연합잡개균다당핵산치료면부격소의뢰성피염적림상료효급안전성.방법 장74례면부격소의뢰성피염환자안치료방법불동분위치료조(38례)화대조조(36례),치료조채용자혈요법연합잡개균다당핵산1ml기육주사,3d1차,4주위1개료정,대조조채용잡개균다당핵산1ml기육주사,3d1차,4주위1개료정.비교량조료효.결과 치료조총유효솔위84.2％(32/38),대조조위63.9％(23/36),량조비교차이유통계학의의(P＜0.05).량조환자균무엄중불량반응발생.결론 자혈요법연합잡개균다당핵산치료면부격소의뢰성피염안전유효.
Objective To observe the clinical effect and security of autohemotherapy combined with bacillus calmette-guerin polysaccharide and nucleic acid in treatment of facial steroid-dependent dermatitis.Methods The 74 patients with facial steroid-dependent dermatitis were divided into treatment group (38patients) and control group (36 patients) according to the treatment method.The patients in treatment group were treated with autohemotherapy combined with bacillus calmette-gnerin polysaccharide and nucleic acid 1 ml muscle injection,every 3 days a time for 4 weeks.The patients in control group were treated with bacillus calmette-guerin polysaccharide and nucleic acid,every 3 days a time for 4 weeks.The effect was compared between the two groups.Results The total effective rate in treatment group was 84.2％(32/38),in control group was 63.9％(23/36),there was significant difference between the two groups (P ＜ 0.05).No serious adverse reaction was found in two groups.Conclusion Autohemotherapy combined with bacillus calmettegnerin polysaccharide and nucleic acid is safe and effective in treatment of facial steroid-dependent dermatitis.