中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
36期
4-7
,共4页
郑乃彩%方渭清%王孝阳%余玲丽
鄭迺綵%方渭清%王孝暘%餘玲麗
정내채%방위청%왕효양%여령려
喉肿瘤%知情同意%焦虑%抑郁%免疫,细胞
喉腫瘤%知情同意%焦慮%抑鬱%免疫,細胞
후종류%지정동의%초필%억욱%면역,세포
Laryngopharynx neoplasms%Informed consent%Anxiety%Depression%Immunity,cellular
目的 探讨喉癌患者本人知情同意对情绪和免疫功能的影响.方法 60例喉癌患者按随机数字表法分为患者本人知情同意组(A组)30例和家属知情同意组(B组)30例.采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评分评估两组患者知情同意前及术后2周焦虑、抑郁程度;检测两组患者知情同意前及术后2周的细胞免疫功能水平.结果 两组知情同意前SAS、SDS评分及细胞免疫功能水平比较差异均无统计学意义(P＞0.05).术后2周,A组SAS、SDS评分分别为(43.17±7.63)、(37.43±8.69)分,均低于B组的(47.84±8.46)、(42.67±9.82)分,差异有统计学意义(P＜0.05);A组术后2周CD3、CD4、NK细胞分别为0.5762±0.0941、0.3832±0.0751和0.1521±0.0491,明显高于B组的0.5160±0.0821、0.3140±0.0561和0.1163±0.0422,差异有统计学意义(P＜0.05),而两组CD8和CD/CD8比较差异无统计学意义(P＞0.05).结论 本人知情同意有利于缓解喉癌患者术后情绪障碍,并可在一定程度上防止免疫功能下降.
目的 探討喉癌患者本人知情同意對情緒和免疫功能的影響.方法 60例喉癌患者按隨機數字錶法分為患者本人知情同意組(A組)30例和傢屬知情同意組(B組)30例.採用焦慮自評量錶(SAS)和抑鬱自評量錶(SDS)評分評估兩組患者知情同意前及術後2週焦慮、抑鬱程度;檢測兩組患者知情同意前及術後2週的細胞免疫功能水平.結果 兩組知情同意前SAS、SDS評分及細胞免疫功能水平比較差異均無統計學意義(P＞0.05).術後2週,A組SAS、SDS評分分彆為(43.17±7.63)、(37.43±8.69)分,均低于B組的(47.84±8.46)、(42.67±9.82)分,差異有統計學意義(P＜0.05);A組術後2週CD3、CD4、NK細胞分彆為0.5762±0.0941、0.3832±0.0751和0.1521±0.0491,明顯高于B組的0.5160±0.0821、0.3140±0.0561和0.1163±0.0422,差異有統計學意義(P＜0.05),而兩組CD8和CD/CD8比較差異無統計學意義(P＞0.05).結論 本人知情同意有利于緩解喉癌患者術後情緒障礙,併可在一定程度上防止免疫功能下降.
목적 탐토후암환자본인지정동의대정서화면역공능적영향.방법 60례후암환자안수궤수자표법분위환자본인지정동의조(A조)30례화가속지정동의조(B조)30례.채용초필자평량표(SAS)화억욱자평량표(SDS)평분평고량조환자지정동의전급술후2주초필、억욱정도;검측량조환자지정동의전급술후2주적세포면역공능수평.결과 량조지정동의전SAS、SDS평분급세포면역공능수평비교차이균무통계학의의(P＞0.05).술후2주,A조SAS、SDS평분분별위(43.17±7.63)、(37.43±8.69)분,균저우B조적(47.84±8.46)、(42.67±9.82)분,차이유통계학의의(P＜0.05);A조술후2주CD3、CD4、NK세포분별위0.5762±0.0941、0.3832±0.0751화0.1521±0.0491,명현고우B조적0.5160±0.0821、0.3140±0.0561화0.1163±0.0422,차이유통계학의의(P＜0.05),이량조CD8화CD/CD8비교차이무통계학의의(P＞0.05).결론 본인지정동의유리우완해후암환자술후정서장애,병가재일정정도상방지면역공능하강.
Objective To investigate the effects of informed consent on emotion and immunologic function in patients with laryngopharynx cancer.Methods Sixty patients with laryngopharynx cancer were divided into group A and group B by random digits table with 30 cases each group.In group A patients were informed consent,and in group B family were informed consent.The self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores,as well as cellular immunity function were measured before informed consent and 2 weeks after surgery.Results The SAS,SDS scores and levels of cellular immunity function between two groups,differences was no statistically significant (P ＞ 0.05).The SAS,SDS scores 2 weeks after surgery in group A were significantly less than those in group B [(43.17 ± 7.63) scores vs.(47.84 ± 8.46) scores,(37.43 ± 8.69) scores vs.(42.67 ± 9.82) scores,P ＜ 0.05].The CD3,CD4,NK cells 2 weeks after surgery in group A were significantly higher than those in group B (0.5762 ±0.0941 vs.0.5160 ± 0.0821,0.3832 ± 0.0751 vs.0.3140 ± 0.0561,0.1521 ± 0.0491 vs.0.1163 ± 0.0422,P ＜ 0.05),CD8 and CD4/CD8 between two groups differences was no statistically significant (P ＞ 0.05).Conclusion The informed consent for patients with laryngopharynx cancer may relieve emotional disorders and avoid immunologic function decreasing.
