中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
36期
24-26
,共3页
子宫内膜异位症%左炔诺孕酮%疼痛%避孕
子宮內膜異位癥%左炔諾孕酮%疼痛%避孕
자궁내막이위증%좌결낙잉동%동통%피잉
Endometriosis%Levonorgestrel%Pain%Contraception
目的 观察子宫内膜异位症术后置左炔诺孕酮宫内节育器的临床疗效.方法 选择经手术和病理确诊的子宫内膜异位症患者84例,均行腹腔镜手术,按随机数字表法分为对照组和治疗组,每组42例.对照组术后仅予短期药物治疗,治疗组在对照组治疗的基础上术后放置左炔诺孕酮宫内节育器.术后随访1年,比较两组疗效. 结果 治疗组随访1年时的疼痛评分为0分,低于对照组的(1.5±0.2)分,差异有统计学意义(P<0.05);治疗组术后术后月经量占术前的比例及癌抗原125水平明显低于对照组[(1l±3)%比(45±6)%、(7.01±2.97) U/L比(38.79±31.43) U/L],差异有统计学意义(P<0.05);治疗组术后病灶复发率为2.38%(1/42),低于对照组的28.57%(12/42),差异有统计学意义(P<0.05).结论 子宫内膜异位症术后置左炔诺孕酮宫内节育器能明显缓解患者术后疼痛,减少月经量,降低病灶复发率,临床疗效显著.
目的 觀察子宮內膜異位癥術後置左炔諾孕酮宮內節育器的臨床療效.方法 選擇經手術和病理確診的子宮內膜異位癥患者84例,均行腹腔鏡手術,按隨機數字錶法分為對照組和治療組,每組42例.對照組術後僅予短期藥物治療,治療組在對照組治療的基礎上術後放置左炔諾孕酮宮內節育器.術後隨訪1年,比較兩組療效. 結果 治療組隨訪1年時的疼痛評分為0分,低于對照組的(1.5±0.2)分,差異有統計學意義(P<0.05);治療組術後術後月經量佔術前的比例及癌抗原125水平明顯低于對照組[(1l±3)%比(45±6)%、(7.01±2.97) U/L比(38.79±31.43) U/L],差異有統計學意義(P<0.05);治療組術後病竈複髮率為2.38%(1/42),低于對照組的28.57%(12/42),差異有統計學意義(P<0.05).結論 子宮內膜異位癥術後置左炔諾孕酮宮內節育器能明顯緩解患者術後疼痛,減少月經量,降低病竈複髮率,臨床療效顯著.
목적 관찰자궁내막이위증술후치좌결낙잉동궁내절육기적림상료효.방법 선택경수술화병리학진적자궁내막이위증환자84례,균행복강경수술,안수궤수자표법분위대조조화치료조,매조42례.대조조술후부여단기약물치료,치료조재대조조치료적기출상술후방치좌결낙잉동궁내절육기.술후수방1년,비교량조료효. 결과 치료조수방1년시적동통평분위0분,저우대조조적(1.5±0.2)분,차이유통계학의의(P<0.05);치료조술후술후월경량점술전적비례급암항원125수평명현저우대조조[(1l±3)%비(45±6)%、(7.01±2.97) U/L비(38.79±31.43) U/L],차이유통계학의의(P<0.05);치료조술후병조복발솔위2.38%(1/42),저우대조조적28.57%(12/42),차이유통계학의의(P<0.05).결론 자궁내막이위증술후치좌결낙잉동궁내절육기능명현완해환자술후동통,감소월경량,강저병조복발솔,림상료효현저.
Objective To observe the clinical efficacy of levonorgestrel intrauterine device (IUD) on endometriosis patients after surgery.Methods Eighty-four endometriosis patients diagnosed by pathological and surgery were divided into control group and treatment group by random digits table with 42 cases each group.The control group was accepted only short-term drug treatment,while the treatment group was placed levonorgestrel intrauterine device on the basis of control group,then comparing the efficacy after followed up for one year.Results The mean pain score of treatment group was 0,control group was (1.5 ±0.2) points,the difference was statistically significant (P< 0.05).The menstrual blood volume and CA125 levels in treatment group were significantly lower than those in control group [(11 ± 3)% vs.(45 ± 6)%,(7.01 ±2.97) U/L vs.(38.79 ±31.43) U/L] (P <0.05).The recurrence rate in treatment group was significantly lower than that in control group [2.38% (1/42) vs.28.57% (12/42),P < 0.05].Conclusion Endometriosis set levonorgestrel IUD after therapy can relieve postoperative pain and reduce menstrual flow,reduce lesion recurrence rate,its clinical effect is significant.