CAJ | 학술논문

目的探讨高压氧治疗不同介入时机和疗程对脑外伤认知功能障碍患者认知功能的影响.方法将90例脑外伤认知功能障碍患者按伤后高压氧治疗介入时机不同分为A组、B组和C组,每组30例;分别于伤后7～14d,15～28 d,＞28 d开始高压氧治疗,每天治疗1次,12次为1个疗程,各组在高压氧治疗前和治疗1,2,3个疗程后采用美国RLA认知功能水平分级标准评定表,评定各组患者的认知功能.结果三组治疗1个疗程后与治疗前RLA分级比较差异无统计学意义(P＞0.05);三组治疗2,3个疗程后与治疗1个疗程后RLA分级比较差异有统计学意义(P＜0.05),三组治疗3个疗程后与治疗2个疗程后RLA分级比较差异有统计学意义(P＜0.05).三组治疗1个疗程后总有效率比较差异无统计学意义(P＞0.05).A组和B组治疗2,3个疗程后总有效率明显高于C组[73.33％(22/30)和66.67％(20/30)比46.67％(14/30),93.33％(28/30)和86.67％(26/30)比60.00％(18/30)],差异有统计学意义(P＜0.05),A组高于B组,但差异无统计学意义(P＞0.05).结论高压氧综合治疗能更有效地改善脑外伤认知功能障碍患者的认知功能,在伤后越早开始高压氧治疗效果越好,并且疗程越长疗效越佳.
목적 탐토고압양치료불동개입시궤화료정대뇌외상인지공능장애환자인지공능적영향.방법 장90례뇌외상인지공능장애환자안상후고압양치료개입시궤불동분위A조、B조화C조,매조30례;분별우상후7～14d,15～28 d,＞28 d개시고압양치료,매천치료1차,12차위1개료정,각조재고압양치료전화치료1,2,3개료정후채용미국RLA인지공능수평분급표준평정표,평정각조환자적인지공능.결과 삼조치료1개료정후여치료전RLA분급비교차이무통계학의의(P＞0.05);삼조치료2,3개료정후여치료1개료정후RLA분급비교차이유통계학의의(P＜0.05),삼조치료3개료정후여치료2개료정후RLA분급비교차이유통계학의의(P＜0.05).삼조치료1개료정후총유효솔비교차이무통계학의의(P＞0.05).A조화B조치료2,3개료정후총유효솔명현고우C조[73.33％(22/30)화66.67％(20/30)비46.67％(14/30),93.33％(28/30)화86.67％(26/30)비60.00％(18/30)],차이유통계학의의(P＜0.05),A조고우B조,단차이무통계학의의(P＞0.05).결론 고압양종합치료능경유효지개선뇌외상인지공능장애환자적인지공능,재상후월조개시고압양치료효과월호,병차료정월장료효월가.
Objective To investigate the effect of hyperbaric oxygen treatment on course of different intervention time,cognitive impairment in patients with traumatic brain injury.Methods Ninety cases of cognitive dysfunction in patients with traumatic brain injury after hyperbaric oxygen in different intervention time were divided into group A,group B and group C,with 30 cases in each group.In 7-14 d,15-28 d,＞ 28 d after injury starting hyperbaric oxygen therapy,treatment 1 time a day,12 times for a course.The cognitive function of patients in three groups before and after 1,2,3 courses of treatment was evaluated by U.S.RLA cognition level classification standard evaluation form.Results Three groups after 1 course of treatment there was no statistically significant difference compared with before treatment RLA grading (P ＞ 0.05).Three groups after 2,3 courses of treatment compared with after 1 course of treatment RLA grading difference was statistically significant (P ＜ 0.05),three groups after 3 courses of treatment compared with after 2 courses of treatment RLA grading difference was statistically significant (P ＜ 0.05).Three groups after 1 course of treatment total effectiveness rate was no statistically significant difference(P ＞ 0.05).Group A and group B after 2,3 courses of treatment total effective rate was significantly higher than that in group C [73.33％ (22/30) and 66.67％ (20/30) vs.46.67 ％(14/30),93.33％ (28/30) and 86.67 ％(26/30) vs.60.00 ％ (18/30),P ＜ 0.05],group A was higher than group B,but there was no statistical significance (P ＞ 0.05).Conclusions Hyperbaric oxygen comprehensive therapy can effectively improve cognitive function in patients with traumatic brain injury cognitive impairment.After the injury,the earlier to start the hyperbaric oxygen therapy,the better effect it has,and the longer the course the better curative effect it has.