中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
24期
55-58
,共4页
刘晶%陈竹林%梁锦辉%毛多喜%陈先锋
劉晶%陳竹林%樑錦輝%毛多喜%陳先鋒
류정%진죽림%량금휘%모다희%진선봉
下咽肿瘤%癌,鳞状细胞%颈淋巴清扫术%淋巴转移%预后
下嚥腫瘤%癌,鱗狀細胞%頸淋巴清掃術%淋巴轉移%預後
하인종류%암,린상세포%경림파청소술%림파전이%예후
Hypopharyngeal neoplasms%Carcinoma,squamous cell%Neck dissection%Lymphatic metastasis%Prognosis
目的 探讨下咽鳞状细胞癌患者择区颈淋巴清扫术检出淋巴结数量与预后的相关性.方法 回顾性分析96例接受择区颈淋巴清扫术的下咽鳞状细胞癌患者的临床资料.结果 全部患者单侧择区颈淋巴清扫检出淋巴结(19.3±11.0)枚,检出阳性淋巴结(0.8±0.6)枚.术前放疗患者(43例)检出淋巴结和检出阳性淋巴结(13.8±7.9)和(0.2±0.2)枚,而未放疗患者(53例)检出淋巴结(23.2±11.9)和(1.0±0.2)枚,两者比较差异有统计学意义(P＜0.01).按检出淋巴结数量将患者分为≤15枚组(42例)和＞15枚组(54例),＞15枚组3年总体生存率、3年无瘤生存率、颈部控制率明显高于≤15枚组[70.4％ (38/54)比38.1％(16/42)、61.1％(33/54)比33.3％(14/42)、96.3％ (52/54)比76.2％(32/42)],差异有统计学意义(P＜0.01或＜0.05).多因素分析发现检出淋巴结＞15枚是影响患者总生存率和无瘤生存率的独立危险因素(P＜0.05).结论 择区颈淋巴清扫术检出淋巴结数量可以用来预测下咽鳞状细胞癌患者的预后.
目的 探討下嚥鱗狀細胞癌患者擇區頸淋巴清掃術檢齣淋巴結數量與預後的相關性.方法 迴顧性分析96例接受擇區頸淋巴清掃術的下嚥鱗狀細胞癌患者的臨床資料.結果 全部患者單側擇區頸淋巴清掃檢齣淋巴結(19.3±11.0)枚,檢齣暘性淋巴結(0.8±0.6)枚.術前放療患者(43例)檢齣淋巴結和檢齣暘性淋巴結(13.8±7.9)和(0.2±0.2)枚,而未放療患者(53例)檢齣淋巴結(23.2±11.9)和(1.0±0.2)枚,兩者比較差異有統計學意義(P＜0.01).按檢齣淋巴結數量將患者分為≤15枚組(42例)和＞15枚組(54例),＞15枚組3年總體生存率、3年無瘤生存率、頸部控製率明顯高于≤15枚組[70.4％ (38/54)比38.1％(16/42)、61.1％(33/54)比33.3％(14/42)、96.3％ (52/54)比76.2％(32/42)],差異有統計學意義(P＜0.01或＜0.05).多因素分析髮現檢齣淋巴結＞15枚是影響患者總生存率和無瘤生存率的獨立危險因素(P＜0.05).結論 擇區頸淋巴清掃術檢齣淋巴結數量可以用來預測下嚥鱗狀細胞癌患者的預後.
목적 탐토하인린상세포암환자택구경림파청소술검출림파결수량여예후적상관성.방법 회고성분석96례접수택구경림파청소술적하인린상세포암환자적림상자료.결과 전부환자단측택구경림파청소검출림파결(19.3±11.0)매,검출양성림파결(0.8±0.6)매.술전방료환자(43례)검출림파결화검출양성림파결(13.8±7.9)화(0.2±0.2)매,이미방료환자(53례)검출림파결(23.2±11.9)화(1.0±0.2)매,량자비교차이유통계학의의(P＜0.01).안검출림파결수량장환자분위≤15매조(42례)화＞15매조(54례),＞15매조3년총체생존솔、3년무류생존솔、경부공제솔명현고우≤15매조[70.4％ (38/54)비38.1％(16/42)、61.1％(33/54)비33.3％(14/42)、96.3％ (52/54)비76.2％(32/42)],차이유통계학의의(P＜0.01혹＜0.05).다인소분석발현검출림파결＞15매시영향환자총생존솔화무류생존솔적독립위험인소(P＜0.05).결론 택구경림파청소술검출림파결수량가이용래예측하인린상세포암환자적예후.
Objective To explore the correlation between the patients with hypopharyngeal squamous cell carcinoma of the selective neck lymph dissection of lymph nodes detected quantity and prognosis.Methods Retrospective analysis of the clinical data of 96 cases underwent selective dissection of cervical lymph node in patients with squamous cell carcinoma of the hypopharynx.Results All patients with unilateral selective neck dissection of lymph nodes detected a number of 19.3 ± 11.0,the number of positive lymph nodes 0.8 ± 0.6.Preoperative radiotherapy patients (43 eases) was detected in lymph nodes and the number of positive lymph nodes was 13.8 ± 7.9 and 0.2 ± 0.2,without radiotherapy patients (53 cases) of lymph nodes detected number 23.2 ± 11.9 and 1.0 ± 0.2,the comparison between the two (P ＜ 0.01).According to the number of positive lymph nodes were divided into ≤ 15 group (42 cases) and ＞ 15 group (54 cases),＞ 15 group,the overall survival rate at 3 years and 3 years disease free survival rate and neck control rate was significandy higher than that of ≤ 15 group [70.4％(38/54) vs.38.1％(16/42),61.1％(33/54) vs.33.3％ (14/42),96.3％(52/54) vs.76.2％(32/42)] (P ＜ 0.01 or ＜ 0.05).Multivariate analysis showed that lymph nodes detected a number ＞ 15 was the survival rate of the independent risk factors for overall survival in patients with and without effect (P ＜ 0.05).Conclusion Selective neck dissection of lymph nodes detected number can be used to predict prognosis in patients with squamous cell carcinoma of the hypopharynx.
